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  1. 202841
    “…The MPO level in the liver, the IL-6, TNF-α, CRP, IL-12, and MMP-9 levels in the plasma, and the serum ALT and AST levels also decreased, thereby reducing LPS/D-GalN-induced liver injury and improving the survival rate of liver-damaged animals within 24 h. CONCLUSIONS: S. sarmentosum extract can alleviate LPS/D-GalN-induced acute liver injury in mice and improve the survival rate of mice. …”
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    Sedum sarmentosum Bunge extract ameliorates lipopolysaccharide- and D-galactosamine-induced acute liver injury by attenuating the hedgehog signaling pathway via regulation of miR-124 expression
  2. 202842
    “…BACKGROUND: Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans infection that damages the skin and subcutis. It is most prevalent in western and central Africa and Australia. …”
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    Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial
  3. 202843
    “…Whole exome sequencing identified a heterozygous mutation in GATA3 (c.1061C>T, p.Pro354Leu), predicted to be damaging. This variant has not been reported in literature or public database to our knowledge. …”
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    SAT-065 A Novel De Novo GATA3 Gene Mutation in an Adolescent with HDR Syndrome
  4. 202844
    “…It is predicted to be deleterious/probably damaging by in silico tools (SIFT, PolyPhen2). Conclusion: To our knowledge, this is the first case demonstrating the presence of a c.571G>A (p.Glu191Lys) variant in the GNA11 gene, in a child with familial hypocalciuric hypercalcemia as well as in his affected mother. …”
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    SAT-340 Familial Hypocalciuric Hypercalcemia Due to a C.571G>A (p.Glu191Lys) Variant in the GNA11 Gene
  5. 202845
    por Atangana, Ernestine, Atangana, Abdon
    Publicado 2020
    “…In the last few months, the spread of COVID-19 among humans has caused serious damages around the globe letting many countries economically unstable. …”
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    Facemasks simple but powerful weapons to protect against COVID-19 spread: Can they have sides effects?
  6. 202846
    “…Few monitoring studies have systematically measured health-damaging air pollutant (ie, fine particulate matter [PM(2·5)] and black carbon) concentrations from a wide range of cooking fuels across diverse populations. …”
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    Household and personal air pollution exposure measurements from 120 communities in eight countries: results from the PURE-AIR study
  7. 202847
    “…This study assessed how nets are allocated within households to individuals of different age categories as ITNs are lost or damaged and as new ITNs are obtained. The study also explored how ITN allocation affects ITN durability. …”
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    The consequences of declining population access to insecticide-treated nets (ITNs) on net use patterns and physical degradation of nets after 22 months of ownership
  8. 202848
    “…Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes. Acta Diabetol. 2010;47(3):193–199.2. …”
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    A Case of Possible SARS-COV-2 Induced Beta-Cell Failure
  9. 202849
    “…Form-Acetic also enabled the detection of damaged DNA via the TUNEL assay using fluorescence. …”
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    Improved preservation of ovarian tissue morphology that is compatible with antigen detection using a fixative mixture of formalin and acetic acid
  10. 202850
    “…BACKGROUND: During skeletal muscle regeneration, satellite stem cells use distinct pathways to repair damaged myofibers or to self-renew by returning to quiescence. …”
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    mRNP granule proteins Fmrp and Dcp1a differentially regulate mRNP complexes to contribute to control of muscle stem cell quiescence and activation
  11. 202851
    “…PROPOSE: Skeletal muscle regenerative capacity fails in restoring muscle function following major injuries in which significant skeletal muscle is lost or damaged. As such, volumetric muscle loss (VML), ultimately results in permanent disability. …”
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    QS6: Collagen-glycosaminoglycans Scaffold Can Improve Muscle Function Recovery After Volumetric Muscle Loss Injury in Rat Model
  12. 202852
    “…We have previously demonstrated that fibronectin is a key extracellular matrix glycoprotein known to be significantly downregulated in radiation-damaged skin. We further identified that an enzymatically crosslinked hydrogel is a suitable construct for incremental fibronectin release in vitro and in murine wound models. …”
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    5: 3D Transglutaminase Fibronectin Hydrogel Therapy Improves the Healing of Chronic Irradiated Porcine Skin Wounds
  13. 202853
    “…This variant is predicted to be damaging/pathogenic in 17/20 in-silico models. However, immunostaining performed on the thyroid tumor tissue of two affected by FNMTC family members revealed intact nuclear expression of MSH2, and microsatellite stable status in both tumors that were tested. …”
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    Co-Occurrence of Familial Non-Medullary Thyroid Cancer (FNMTC) and Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Associated Tumors—A Cohort Study
  14. 202854
    “…Autophagy leads to an accumulation of damaged mitochondria by autophagosomes. An acidic environment is maintained in compartments of cells, such as autophagosomes, late endosomes, and lysosomes; these organelles belong to the “acid store” of the cells. …”
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    ATPase Activity of the Subcellular Fractions of Colorectal Cancer Samples under the Action of Nicotinic Acid Adenine Dinucleotide Phosphate
  15. 202855
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    Telerobotic interventions from a distance: an initial experience in 3D phantom mapping
  16. 202856
    “…However, 2-methoxyestradiol improved bone-vessel metabolism of aged mice while damaged that of young mice. Mechanically, HIF1α showed opposed effects in regulating the cell migration and osteogenesis–angiogenesis coupling of YBMSCs and ABMSCs, but no remarked effect on the proliferation of either cell type. …”
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    A dual role of HIF1α in regulating osteogenesis–angiogenesis coupling
  17. 202857
    “…Using stem cells (e.g., human umbilical cord blood mesenchymal stem cells) is currently a potent medical approach for modulating the impact of neural damages and regeneration of spinal cord injuries. …”
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    Large-scale analysis of MicroRNA expression in motor neuron-like cells derived from human umbilical cord blood mesenchymal stem cells
  18. 202858
    “…Perlecan domain V promotes reconstitution of the blood brain barrier damaged by ischemic stroke and is neurogenic and neuroprotective. …”
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    Perlecan, A Multi-Functional, Cell-Instructive, Matrix-Stabilizing Proteoglycan With Roles in Tissue Development Has Relevance to Connective Tissue Repair and Regeneration
  19. 202859
    “…BACKGROUND: There is an unfulfilled need to find the best way to automatically capture, analyze, organize, and merge structural and functional brain magnetic resonance imaging (MRI) data to ultimately extract relevant signals that can assist the medical decision process at the bedside of patients in postanoxic coma. …”
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    Multimodal MRI-Based Whole-Brain Assessment in Patients In Anoxoischemic Coma by Using 3D Convolutional Neural Networks
  20. 202860
    “…However, the extent to which this energy penetrates the adjacent tissue, potentially damaging nearby vasculature and osteocytes, is unknown. …”
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    Poster 110: Depth of Tissue Necrosis Following Footprint Preparation with Arthroscopic Radiofrequency Ablation
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