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421“…Mechanistically, our findings demonstrated that induction of DNA damage and inactivation of DNA damage response were involved in the synergistic interaction of the drug combination regimen. …”
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422por Kozmin, Stanislav G., Sedletska, Yuliya, Reynaud-Angelin, Anne, Gasparutto, Didier, Sage, Evelyne“…Using a variety of model multiply damaged sites (MDS), we investigated parameters that govern the formation of DSB during the processing of MDS. …”
Publicado 2009
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423por Michelini, Flavia, Pitchiaya, Sethuramasundaram, Vitelli, Valerio, Sharma, Sheetal, Gioia, Ubaldo, Pessina, Fabio, Cabrini, Matteo, Wang, Yejun, Capozzo, Ilaria, Iannelli, Fabio, Matti, Valentina, Francia, Sofia, Shivashankar, G.V., Walter, Nils G., d’Adda di Fagagna, Fabrizio“…The DNA damage response (DDR) preserves genomic integrity. …”
Publicado 2017
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424por Okamoto, Keiji, Ohishi, Tomokazu, Kuroiwa, Mika, Iemura, Shun-ichiro, Natsume, Tohru, Seimiya, Hiroyuki“…These observations suggest that tankyrase plays a role in the DNA damage repair response and implicates a potential therapeutic utility of tankyrase inhibitors in combination treatments with DNA-damaging anticancer drugs.…”
Publicado 2018
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425por Metzler-Baddeley, Claudia, Mole, Jilu P., Sims, Rebecca, Fasano, Fabrizio, Evans, John, Jones, Derek K., Aggleton, John P., Baddeley, Roland J.“…The first class of models emphasises the importance of gray matter: age and risk-related processes cause neurodegeneration and this causes damage in associated white matter tracts. The second class of models reverses the direction of causation: aging and risk factors cause white matter damage and this leads to gray matter damage. …”
Publicado 2019
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426por Marchetti, Monia“…This review also highlights potential targets for prevention and therapy of COVID-19-related organ damage and discusses the role of marketed drugs, such as eculizumab and imatinib, as suitable candidates for clinical trials.…”
Publicado 2020
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427por Zhang, Hao, Ma, Jie, Shen, Jie, Lan, Yan, Ding, Lili, Qian, Shulou, Xia, Weidong, Cheng, Cheng, Chu, Paul K.“…The new results provide insights into the mechanism of multiple plasma-induced damage to bacteria and cells as well as the disinfection mechanism.…”
Publicado 2018
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428“…The objective of this paper is to perform a systematic review to summarize the electroencephalogram (EEG) findings in patients with coronavirus disease (COVID-19) and databases and tools used in artificial intelligence algorithms, supporting the diagnosis and correlation between lung disease and brain damage, and lung damage. Available search tools containing scientific publications, such as PubMed and Google Scholar, were comprehensively evaluated and searched with open databases and tools used in AI algorithms. …”
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439por Gibson, S M“…As the radiation dose accumulates, the first effects of radiation damage are now observable in the silicon sensors. …”
Publicado 2011
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440por Gibson, S M“…As the radiation dose accumulates, the first effects of radiation damage are now observable in the silicon sensors. …”
Publicado 2011
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