“…DNA damage induced by various reactive oxygen species can be characterized using a set of repair endonucleases with defined substrate specificities. …”
Enlace del recurso
Enlace del recurso

“…Angiotensin-converting enzyme has been found to be elevated in bronchoalveolar washings from animals with endothelial cell damage in the pulmonary capillaries. The correlation of these cellular and biochemical alterations in the bronchoalveolar lavage fluid with morphological indications of damage has served to validate this method of detecting acute lung injury. …”
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…Two recent studies, using different experimental platforms, provide insight into new pathways involved in the response of yeast to DNA damage.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso

Enlace del recurso

“…Conclusions based on these observations are the following: (a) damage is physically expressed only at anaphase; (b) a gap region is composed of two subunits, each of which is about 800–1000 A in diameter and may correspond to a half-chromatid structure; (c) the ends of acentric fragments are structurally similar to normal chromosome ends, except where the break occurs in a specific region such as the secondary constriction; (d) at metaphase the fragment and the main portion of the chromosome move as a single unit to the equator, and the two units are disconnected only at the onset of anaphase; (e) sidearm bridges appear to be exchanges, involving a subchromatid unit. …”
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…These data indicate that, under conditions for which extensive F-actin filament cross-linking (fixing) occurs, the filaments become damaged due to the concurrent formation of intrasubunit cross-links that cause local depolymerization and distortion and that tropomyosin protects against this damage.…”
Enlace del recurso
Enlace del recurso

“…The nature of short term iron-induced liver damage and its effect on the hepatic damage induced by other toxins have been studied by the use of histochemical techniques. …”
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…Simultaneous incubation with human S9 liver enzyme mix ablated the damaging effect of the extracts. Our data show that fern spore extracts can cause DNA damage in human cells in vitro. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A new study shows that short-term chemotherapy causes not only acute injury to progenitor cells, but also delayed damage to myelin.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…Many physical and chemical agents used in anti-neoplastic therapy are known to act by effecting DNA damage. The possibility that calmodulin may be an important modulator of the response to DNA damage in eukaryotic cells has been explored in a number of studies which use calmodulin antagonists in combination with agents known to damage DNA. …”
Enlace del recurso
Enlace del recurso

“…The result was demonstrated that the in situ DNA damage was detected by differential pulse voltammetry after the o-nitrophenol was electrochemically reduced.…”
Enlace del recurso
Enlace del recurso