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761“…BACKGROUND: This study aimed to analyze the clinicopathological characteristics of patients with paraproteinemia and renal damage. METHODS: Ninety-six patients from 2014 to 2018 with paraproteinemia and renal damage were enrolled and the clinical data, renal pathology, treatment and prognosis data were collected. …”
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763por ter Haar, Nienke M, van Delft, Amber Laetitia Justine, Annink, Kim Valerie, van Stel, Henk, Al-Mayouf, Sulaiman M, Amaryan, Gayane, Anton, Jordi, Barron, Karyl S, Benseler, Susanne, Brogan, Paul A, Cantarini, Luca, Cattalini, Marco, Cochino, Alexis-Virgil, de Benedetti, Fabrizio, Dedeoglu, Fatma, de Jesus, Adriana Almeida, Demirkaya, Erkan, Dolezalova, Pavla, Durrant, Karen L, Fabio, Giovanna, Gallizzi, Romina, Goldbach-Mansky, Raphaela, Hachulla, Eric, Hentgen, Veronique, Herlin, Troels, Hofer, Michaël, Hoffman, Hal M, Insalaco, Antonella, Jansson, Annette F, Kallinich, Tilmann, Kone-Paut, Isabelle, Kozlova, Anna, Kuemmerle-Deschner, Jasmin Beate, Lachmann, Helen J, Laxer, Ronald M, Martini, Alberto, Nielsen, Susan, Nikishina, Irina, Ombrello, Amanda K, Özen, Seza, Papadopoulou-Alataki, Efimia, Quartier, Pierre, Rigante, Donato, Russo, Ricardo, Simon, Anna, Trachana, Maria, Uziel, Yosef, Ravelli, Angelo, Schulert, Grant, Gattorno, Marco, Frenkel, Joost“…INTRODUCTION: Autoinflammatory diseases can cause irreversible tissue damage due to systemic inflammation. Recently, the Autoinflammatory Disease Damage Index (ADDI) was developed. …”
Publicado 2018
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764por Kuisma, Heli, Bramante, Simona, Rajamäki, Kristiina, Sipilä, Lauri J., Kaasinen, Eevi, Kaukomaa, Jaana, Palin, Kimmo, Mäkinen, Netta, Sjöberg, Jari, Sarvilinna, Nanna, Taipale, Jussi, Kauppi, Liisa, Tumiati, Manuela, Hassinen, Antti, Pitkäniemi, Janne, Jalkanen, Jyrki, Heikkinen, Sanna, Pasanen, Annukka, Heikinheimo, Oskari, Bützow, Ralf, Välimäki, Niko, Aaltonen, Lauri A.“…Mechanical forces in a constrained cellular environment were recently established as a facilitator of chromosomal damage. Whether this could contribute to tumorigenesis is not known. …”
Publicado 2021
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766“…The disc damage likelihood scale (DDLS) is a tool for classifying glaucomatous structural changes to the optic disc based on the radial width of the neuroretinal rim at its thinnest location, or if no rim is present, the extent of absence of the rim. …”
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767“…Consequently, epithelial cells communicate with multiple cell types including immune cells and fibroblasts to promote acute inflammation and normal wound healing in response to damage. However, aberrant epithelial cell death and damage are hallmarks of pulmonary disease, with necrotic cell death and cellular senescence contributing to disease pathogenesis in numerous respiratory diseases such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and coronavirus disease (COVID)-19. …”
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768por Sirufo, Maria Maddalena, Catalogna, Alessandra, Raggiunti, Martina, De Pietro, Francesca, Galeoto, Giovanni, Bassino, Enrica Maria, Ginaldi, Lia, De Martinis, Massimo“…The aim of this study is to correlate the capillaroscopic findings by nailfold video capillaroscopy (NVC) to volleyball practice in order to early detect possible anomalies and perform an adequate follow-up to avoid damages that could negatively affect sport practice and the players’ health status. …”
Publicado 2021
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769por Brill, Jason B., Brenner, Megan, Duchesne, Juan, Roberts, Derek, Ferrada, Paula, Horer, Tal, Kauvar, David, Khan, Mansoor, Kirkpatrick, Andrew, Ordonez, Carlos, Perreira, Bruno, Priouzram, Artai, Cotton, Bryan A.Enlace del recurso
Publicado 2021
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770“…The nervous system is vulnerable to genomic instability and mutations in DNA damage response factors lead to numerous developmental and progressive neurological disorders. …”
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771por Chen, Si, Wan, Liqing, Couch, Letha, Lin, Haixia, Li, Yan, Dobrovolsky, Vasily N., Mei, Nan, Guo, Lei“…In addition, DNA damage was also observed when cells were treated with commercially available goldenseal extracts and the extent of DNA damage was positively correlated to the berberine content. …”
Publicado 2013
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772por Takahama, Yousuke“…Med. https://doi.org/10.1084/jem.20211239) now demonstrate that prolonged damage in thymic medullary epithelial cells causes the failure in self-tolerance in newly generated T cells and provokes post-transplant autoimmunity.…”
Publicado 2021
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773“…Here, we aim to provide a comprehensive review of the current evidence regarding the mechanisms of neuronal damage in AHPs.…”
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774por Peze-Heidsieck, Eugenie, Bonnifet, Tom, Znaidi, Rania, Ravel-Godreuil, Camille, Massiani-Beaudoin, Olivia, Joshi, Rajiv L., Fuchs, Julia“…We will discuss in this review the potential contribution of LINE-1 elements in inducing DNA damage and genomic instability, which are emerging pathological features in NDs. …”
Publicado 2022
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775“…The secondary structure altercation of the protein molecules of the PNN was analyzed to evaluate damage intensity under varying shock speeds. At a higher shock speed, damage intensity is more elevated, and hyaluronan (glycan molecule) is most likely to break at the rigid junction. …”
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776“…Natural hazards have caused damages to structures and economic losses worldwide. …”
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777por Zhao, Shihong, Xu, Boya, Ma, Wenbin, Chen, Hao, Jiang, Chuanlu, Cai, Jinquan, Meng, Xiangqi“…Therefore, in this review, first, we will describe the common pathways of DNA damage repair. Second, we will focus on immunotherapy and analyze the mechanisms of DNA damage repair involved in the immune process. …”
Publicado 2022
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778“…DNA damage response (DDR) is critical to ensure genome stability, and defects in this signaling pathway are highly associated with carcinogenesis and tumor progression. …”
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779por Herate, Cecile, Brochard, Patricia, De Vathaire, Florent, Ricoul, Michelle, Martins, Bernadette, Laurier, Laurence, Deverre, Jean-Robert, Thirion, Bertrand, Hertz-Pannier, Lucie, Sabatier, Laure“…BACKGROUND: Magnetic resonance imaging (MRI) is currently considered a safe imaging technique because, unlike computed tomography, MRI does not expose patients to ionising radiation. …”
Publicado 2022
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780por Ahmed, Abdulrahman K., Sayad, Reem, Mahmoud, Islam A., EL-Monem, Aya M. Abd, Badry, Salma H., Ibrahim, Islam H., Hafez, Mahmoud HR, El-Mokhtar, Mohamed A., Sayed, Ibrahim M.Enlace del recurso
Publicado 2022
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