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1461por Stavrou, George, Tzikos, Georgios, Menni, Alexandra-Eleftheria, Chatziantoniou, Georgios, Vouchara, Aggeliki, Fyntanidou, Barbara, Grosomanidis, Vasilios, Kotzampassi, KaterinaEnlace del recurso
Publicado 2022
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1462por Wang, Yuqian, Huang, Yingjian, Fu, Yu, Guo, Zhixiong, Chen, Da, Cao, Fangxian, Ye, Qi, Duan, Qiqi, Liu, Meng, Wang, Ning, Han, Dan, Qu, Chaoyi, Tian, Zhimin, Qu, Yongquan, Zheng, Yan“…Herein, we demonstrate a reductive-damage strategy to enable tumor therapy by the inhibition of protective autophagy via the catalytic scavenging of ROS using porous nanorods of ceria (PN-CeO(2)) nanozymes as autophagy inhibitor. …”
Publicado 2022
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1463por Zhu, Jiahui, Liu, Lexin, Ma, Xiaodi, Cao, Xinyu, Chen, Yu, Qu, Xiangping, Ji, Ming, Liu, Huijun, Liu, Chi, Qin, Xiaoqun, Xiang, Yang“…Given that the lung is exposed to the external environment, it is likely that oxidative stress, especially the stimulation of DNA, would be of particular importance in pulmonary fibrosis. DNA damage is known to play an important role in idiopathic pulmonary fibrosis initiation, so DNA repair systems targeting damage are also crucial for the survival of lung cells. …”
Publicado 2022
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1464por Młodziński, Krzysztof, Świątczak, Michał, Rohun, Justyna, Wolf, Jacek, Narkiewicz, Krzysztof, Hellmann, Marcin, Daniłowicz-Szymanowicz, Ludmiła“…NTBI can induce the production of reactive oxygen species (ROS), which induce lipid peroxidation and mediate iron-related damage as the elements of oxidative stress in many tissues, including heart and vessels’ mitochondria. …”
Publicado 2022
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1465por Ahn, Ji-Su, Shin, Ye Young, Oh, Su-Jeong, Song, Min-Hye, Kang, Min-Jung, Park, So Yeong, Nguyen, Phuong Thao, Nguyen, Dang Khoa, Kim, Hyoung Kyu, Han, Jin, Vasileva, Elena A., Mishchenko, Natalia P., Fedoreyev, Sergey A., Stonik, Valentin A., Seo, Yoojin, Lee, Byung-Chul, Kim, Hyung-SikEnlace del recurso
Publicado 2022
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1466“…Further, in addition to DNA-damage-directed therapies, subsets of Ewing tumors may be more susceptible to DNA-damage/immunotherapy combinations given the significant cross-talk between DNA damage and inflammatory pathways in the tumor microenvironment. …”
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1467“…Strikingly, the differentially abundant proteins were highly enriched in the respiratory chain, oxidative phosphorylation, and the synaptic vesicle cycle, which might lead to oxidative damage and synaptic dysfunction. The results of this study provide valuable information to better understand the mechanisms of depressive-like behavior induced by confined environments.…”
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1468por da Silva¹, Bruna Ramos, Orsso¹, Camila E., Gonzalez², Maria Cristina, Sicchieri³, Juliana Maria Faccioli, Mialich³, Mirele Savegnago, Jordao³, Alceu A., Prado, Carla M.“…As inflammation and oxidative stress can damage cellular structures, phase angle has potential utility in early detecting inflammatory and oxidative status. …”
Publicado 2022
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1469por Pacella, Valentina, Scandola, M., Bà, M., Smania, N., Beccherle, M., Rossato, E., Volpe, D., Moro, Valentina“…Indeed, the left hemisphere damaged patients find it difficult to estimate 4500 ms or longer durations, while the right hemisphere damaged patients fail in 3000 ms durations. …”
Publicado 2022
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1471por Magliozzi, Roberta, Fadda, Giulia, Brown, Robert A., Bar‐Or, Amit, Howell, Owain W., Hametner, Simon, Marastoni, Damiano, Poli, Alberto, Nicholas, Richard, Calabrese, Massimiliano, Monaco, Salvatore, Reynolds, Richard“…SUMMARY FOR SOCIAL MEDIA: Imaging and neuropathological evidences demonstrated the unique feature of “surface‐in” gradient of damage in multiple sclerosis (MS) since early pediatric stages, often associated with more severe brain atrophy and disease progression. …”
Publicado 2022
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1472por Urowitz, Murray B., Aranow, Cynthia, Asukai, Yumi, Bass, Damon L., Bruce, Ian N., Chauhan, Deven, Dall'Era, Maria, Furie, Richard, Fox, Norma Lynn, Gilbride, Jennifer A., Hammer, Anne, Ginzler, Ellen M., Gonzalez‐Rivera, Tania, Levy, Roger A., Merrill, Joan T., Quasny, Holly, Roth, David A., Stohl, William, van Vollenhoven, Ronald, Wallace, Daniel J., Petri, Michelle“…Organ damage is a key determinant of poor long‐term prognosis and early death in patients with systemic lupus erythematosus (SLE). …”
Publicado 2022
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1473por Sophocleous, Antonia, Azfer, Asim, Huesa, Carmen, Stylianou, Eleni, Ralston, Stuart H.“…We conclude that treatment with probiotics following FMT in mice where the microbiome has been depleted inhibits DMM-induced cartilage damage and impacts on the structure of subchondral bone particularly at the femoral condyle. …”
Publicado 2022
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1474por Dinache, Georgiana, Popescu, Claudiu Costinel, Mogoșan, Corina, Enache, Luminita, Agache, Mihaela, Codreanu, Cătălin“…ILD develops within approximately 5 years from RA diagnosis, and ILD-associated imaging findings on chest X-rays and HR-CT are more prevalent among men with RA, among patients with positive RA serology (RF and/or ACPA) and RA patients on methotrexate.…”
Publicado 2022
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1475por Atencio-García, Víctor, Padilla-Izquierdo, Denia, Robles-González, Juana, Prieto-Guevara, Martha, Pardo-Carrasco, Sandra, Espinosa-Araujo, José“…Sperm kinetics and damage in fresh, pre-frozen, and thawed semen were evaluated. …”
Publicado 2023
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1476“…Sperm defects in the form of coiled tail, absence of acrosome and shapeless head and a significant DNA damage in the testes were recorded. The frequency of sperm abnormalities reached 11.06 ± 0.14 after treatment with highest tested dose (6 mg/kg) vs 3.04 ± 0.19 for control. …”
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1477por Abd El-Hafeez, Amer Ali, Sun, Nina, Chakraborty, Anirban, Ear, Jason, Roy, Suchismita, Chamarthi, Pranavi, Rajapakse, Navin, Das, Soumita, Luker, Kathryn E., Hazra, Tapas K., Luker, Gary D., Ghosh, Pradipta“…Because GIV selectively binds other BRCT-containing proteins suggests that G-proteins may fine-tune sensing, repair, and survival after diverse types of DNA damage.…”
Publicado 2023
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1478por Kufner, Corinna L., Krebs, Stefan, Fischaleck, Marlis, Philippou-Massier, Julia, Blum, Helmut, Bucher, Dominik B., Braun, Dieter, Zinth, Wolfgang, Mast, Christof B.“…Understanding the sequence-dependent DNA damage formation requires probing a complete pool of sequences over a wide dose range of the damage-causing exposure. …”
Publicado 2023
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1479por Donate-Correa, Javier, Martín-Carro, Beatriz, Cannata-Andía, Jorge B., Mora-Fernández, Carmen, Navarro-González, Juan F.“…This review focuses on the pathogenic mechanisms related to the appearance of oxidative stress damage and mitochondrial dysfunction in kidney disease. …”
Publicado 2023
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1480por Toussirot, Eric“…Both RA and ax SpA are characterized by a chronic course with progressive structural modifications, namely, cartilage damage and bone erosions in RA and osteoproliferative changes with spinal ossifications in ax SpA. …”
Publicado 2023
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