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1Male-killing symbiont damages host's dosage-compensated sex chromosome to induce embryonic apoptosis“…Transcriptomic analysis reveals that many genes related to DNA damage and apoptosis are up-regulated specifically in infected male embryos. …”
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2por Stampone, Emanuela, Bencivenga, Debora, Barone, Clementina, Aulitto, Arianna, Verace, Federica, Della Ragione, Fulvio, Borriello, Adriana“…The effects of LiCl treatment were investigated in SH-SY5Y, a human neuroblastoma cell line and an in vitro model of dopaminergic neuronal differentiation. LiCl, at the dosage used in psychiatric treatment, does not affect cell proliferation, while at higher doses it delays the SH-SY5Y cell division cycle and for prolonged usage reduces cell viability. …”
Publicado 2020
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3por Huang, Zhizhou, Zhou, Xueqiong, He, Yangfan, Ke, Xiangyu, Wen, Ying, Zou, Fei, Chen, Xuemei“…One hepatic cell line (L02) and two HCC cell lines (Huh7 and HepG2) were heated at 42 °C for 0, 0.5 or 4 h with or without 100 nM 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG). HCC cells of the combination group exhibited more G2/M arrest and higher apoptotic rates which might result from suffering from more reactive oxygen species and serious DNA damage. …”
Publicado 2016
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4por Liang, Dun, Burkhart, Sarah Lyn, Singh, Rakesh Kumar, Kabbaj, Marie-Helene Miquel, Gunjan, Akash“…We have investigated the effect of altering histone dosage on DNA repair in budding yeast. An increase in histone gene dosage resulted in enhanced DNA damage sensitivity, whereas deletion of a H3–H4 gene pair resulted in reduced levels of free H3 and H4 concomitant with resistance to DNA damaging agents, even in mutants defective in the DNA damage checkpoint. …”
Publicado 2012
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5por Gibbs-Seymour, Ian, Oka, Yasuyoshi, Rajendra, Eeson, Weinert, Brian T., Passmore, Lori A., Patel, Ketan J., Olsen, Jesper V., Choudhary, Chunaram, Bekker-Jensen, Simon, Mailand, Niels“…Our results uncover a regulatory role for SUMOylation in the FA pathway, and we propose that ubiquitin-SUMO signaling circuitry is a mechanism that contributes to the balance of activated ID complex dosage at sites of DNA damage.…”
Publicado 2015
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6por Ahmed, Asif“…How to cite this article: Ahmed A. Corona Collateral Damage Syndrome: Perception of the Damage. Indian J Crit Care Med 2021;25(4):358–359.…”
Publicado 2021
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8por Haas, Drago, Thamm, Antje M., Sun, Jiayi, Huang, Lili, Sun, Lijie, Beaudoin, Guillaume A. W., Wise, Kim S., Lerma-Ortiz, Claudia, Bruner, Steven D., Breuer, Marian, Luthey-Schulten, Zaida, Lin, Jiusheng, Wilson, Mark A., Brown, Greg, Yakunin, Alexander F., Kurilyak, Inna, Folz, Jacob, Fiehn, Oliver, Glass, John I., Hanson, Andrew D., Henry, Christopher S., de Crécy-Lagard, Valérie“…This extension revealed that several key metabolite damage control systems remain to be identified in JCVI-Syn3A, such as that for methylglyoxal.…”
Publicado 2022
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12“…a) Radiation damage in organic materials. This series of lectures will give an overview of radiation effects on materials and components frequently used in accelerator engineering and experiments. …”
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14por Monte, Ines Paola, Cameli, Matteo, Losi, Valentina, Privitera, Fiorella, Citro, Rodolfo“…Echocardiography is the optimal imaging technique for diagnostic and therapeutic management. …”
Publicado 2020
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19“…Recent work has achieved the feat of activating the DNA damage checkpoint in the absence of DNA damage, revealing the importance of protein-chromatin associations for the activation, amplification and maintenance of the DNA damage response.…”
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20por Popp, Henning D., Kohl, Vanessa, Naumann, Nicole, Flach, Johanna, Brendel, Susanne, Kleiner, Helga, Weiss, Christel, Seifarth, Wolfgang, Saussele, Susanne, Hofmann, Wolf-Karsten, Fabarius, Alice“…DNA damage and alterations in the DNA damage response (DDR) are critical sources of genetic instability that might be involved in BCR-ABL1 kinase-mediated blastic transformation of chronic myeloid leukemia (CML). …”
Publicado 2020
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