The alternative splicing factor Nova2 regulates vascular development and lumen formation

por Giampietro, Costanza, Deflorian, Gianluca, Gallo, Stefania, Di Matteo, Anna, Pradella, Davide, Bonomi, Serena, Belloni, Elisa, Nyqvist, Daniel, Quaranta, Valeria, Confalonieri, Stefano, Bertalot, Giovanni, Orsenigo, Fabrizio, Pisati, Federica, Ferrero, Elisabetta, Biamonti, Giuseppe, Fredrickx, Evelien, Taveggia, Carla, Wyatt, Chris D. R., Irimia, Manuel, Di Fiore, Pier Paolo, Blencowe, Benjamin J., Dejana, Elisabetta, Ghigna, Claudia
Publicado 2015

Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication

por Stegmann, Kim M., Dickmanns, Antje, Heinen, Natalie, Blaurock, Claudia, Karrasch, Tim, Breithaupt, Angele, Klopfleisch, Robert, Uhlig, Nadja, Eberlein, Valentina, Issmail, Leila, Herrmann, Simon T., Schreieck, Amelie, Peelen, Evelyn, Kohlhof, Hella, Sadeghi, Balal, Riek, Alexander, Speakman, John R., Groß, Uwe, Görlich, Dirk, Vitt, Daniel, Müller, Thorsten, Grunwald, Thomas, Pfaender, Stephanie, Balkema-Buschmann, Anne, Dobbelstein, Matthias
Publicado 2022

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

por Zhang, Lin, Orban, Martin, Lorenz, Michael, Barocke, Verena, Braun, Daniel, Urtz, Nicole, Schulz, Christian, von Brühl, Marie-Luise, Tirniceriu, Anca, Gaertner, Florian, Proia, Richard L., Graf, Thomas, Bolz, Steffen-Sebastian, Montanez, Eloi, Prinz, Marco, Müller, Alexandra, von Baumgarten, Louisa, Billich, Andreas, Sixt, Michael, Fässler, Reinhard, von Andrian, Ulrich H., Junt, Tobias, Massberg, Steffen
Publicado 2012

Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy

por Gramlich, Michael, Pane, Luna Simona, Zhou, Qifeng, Chen, Zhifen, Murgia, Marta, Schötterl, Sonja, Goedel, Alexander, Metzger, Katja, Brade, Thomas, Parrotta, Elvira, Schaller, Martin, Gerull, Brenda, Thierfelder, Ludwig, Aartsma-Rus, Annemieke, Labeit, Siegfried, Atherton, John J, McGaughran, Julie, Harvey, Richard P, Sinnecker, Daniel, Mann, Matthias, Laugwitz, Karl-Ludwig, Gawaz, Meinrad Paul, Moretti, Alessandra
Publicado 2015

Cardiomyopathy with lethal arrhythmias associated with inactivation of KLHL24

por Hedberg-Oldfors, Carola, Abramsson, Alexandra, Osborn, Daniel P S, Danielsson, Olof, Fazlinezhad, Afsoon, Nilipour, Yalda, Hübbert, Laila, Nennesmo, Inger, Visuttijai, Kittichate, Bharj, Jaipreet, Petropoulou, Evmorfia, Shoreim, Azza, Vona, Barbara, Ahangari, Najmeh, López, Marcela Dávila, Doosti, Mohammad, Banote, Rakesh Kumar, Maroofian, Reza, Edling, Malin, Taherpour, Mehdi, Zetterberg, Henrik, Karimiani, Ehsan Ghayoor, Oldfors, Anders, Jamshidi, Yalda
Publicado 2019

Pleckstrin-2 is essential for erythropoiesis in β-thalassemic mice, reducing apoptosis and enhancing enucleation

por Feola, Maria, Zamperone, Andrea, Moskop, Daniel, Chen, Huiyong, Casu, Carla, Lama, Dechen, Di Martino, Julie, Djedaini, Mansour, Papa, Luena, Martinez, Marc Ruiz, Choesang, Tenzin, Bravo-Cordero, Jose Javier, MacKay, Matthew, Zumbo, Paul, Brinkman, Nathan, Abrams, Charles S., Rivella, Stefano, Hattangadi, Shilpa, Mason, Christopher E., Hoffman, Ronald, Ji, Peng, Follenzi, Antonia, Ginzburg, Yelena Z.
Publicado 2021

Engineering sorghum for higher 4-hydroxybenzoic acid content

por Lin, Chien-Yuan, Tian, Yang, Nelson-Vasilchik, Kimberly, Hague, Joel, Kakumanu, Ramu, Lee, Mi Yeon, Pidatala, Venkataramana R., Trinh, Jessica, De Ben, Christopher M., Dalton, Jutta, Northen, Trent R., Baidoo, Edward E.K., Simmons, Blake A., Gladden, John M., Scown, Corinne D., Putnam, Daniel H., Kausch, Albert P., Scheller, Henrik V., Eudes, Aymerick
Publicado 2022

Identification of immunodominant T cell epitopes induced by natural Zika virus infection

por Eickhoff, Christopher S., Meza, Krystal A., Terry, Frances E., Colbert, Chase G., Blazevic, Azra, Gutiérrez, Andres H., Stone, E. Taylor, Brien, James D., Pinto, Amelia K., El Sahly, Hana M., Mulligan, Mark J., Rouphael, Nadine, Alcaide, Maria L., Tomashek, Kay M., Focht, Chris, Martin, William D., Moise, Leonard, De Groot, Anne S., Hoft, Daniel F.
Publicado 2023

Expanding spectrum, intrafamilial diversity, and therapeutic challenges from 15 patients with heterozygous CARD11-associated diseases: A single center experience

por Urdinez, Luciano, Erra, Lorenzo, Palma, Alejandro M., Mercogliano, María F., Fernandez, Julieta Belén, Prieto, Emma, Goris, Verónica, Bernasconi, Andrea, Sanz, Marianela, Villa, Mariana, Bouso, Carolina, Caputi, Lucia, Quesada, Belen, Solis, Daniel, Aguirre Bruzzo, Anabel, Katsicas, Maria Martha, Galluzzo, Laura, Weyersberg, Christian, Bocian, Marcela, Bujan, Maria Marta, Oleastro, Matías, Almejun, María B., Danielian, Silvia
Publicado 2022

NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss

por Schlett, Judith Stefanie, Mettang, Melanie, Skaf, Aladdin, Schweizer, Pavel, Errerd, Alina, Mulugeta, Ephraim Alemayehu, Hein, Tabea Melissa, Tsesmelis, Konstantinos, Tsesmelis, Miltiadis, Büttner, Ulrike F. G., Wendt, Heinrich, Abaei, Alireza, Rasche, Volker, Prex, Vivien, Nespoli, Ester, Alami, Najwa Ouali, Tews, Daniel, Walther, Paul, Yilmazer-Hanke, Deniz, Oswald, Franz, Dimou, Leda, Wirth, Thomas, Baumann, Bernd
Publicado 2023

No Overt Clinical Immunodeficiency Despite Immune Biological Abnormalities in Patients With Constitutional Mismatch Repair Deficiency

por Tesch, Victoria K., IJspeert, Hanna, Raicht, Andrea, Rueda, Daniel, Dominguez-Pinilla, Nerea, Allende, Luis M., Colas, Chrystelle, Rosenbaum, Thorsten, Ilencikova, Denisa, Baris, Hagit N., Nathrath, Michaela H. M., Suerink, Manon, Januszkiewicz-Lewandowska, Danuta, Ragab, Iman, Azizi, Amedeo A., Wenzel, Soeren S., Zschocke, Johannes, Schwinger, Wolfgang, Kloor, Matthias, Blattmann, Claudia, Brugieres, Laurence, van der Burg, Mirjam, Wimmer, Katharina, Seidel, Markus G.
Publicado 2018

Coronin 1 Regulates Cognition and Behavior through Modulation of cAMP/Protein Kinase A Signaling

por Jayachandran, Rajesh, Liu, Xiaolong, BoseDasgupta, Somdeb, Müller, Philipp, Zhang, Chun-Lei, Moshous, Despina, Studer, Vera, Schneider, Jacques, Genoud, Christel, Fossoud, Catherine, Gambino, Frédéric, Khelfaoui, Malik, Müller, Christian, Bartholdi, Deborah, Rossez, Helene, Stiess, Michael, Houbaert, Xander, Jaussi, Rolf, Frey, Daniel, Kammerer, Richard A., Deupi, Xavier, de Villartay, Jean-Pierre, Lüthi, Andreas, Humeau, Yann, Pieters, Jean
Publicado 2014

Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production

por Chen, Helen, Victor, A. Kaitlyn, Klein, Jonathon, Tacer, Klementina Fon, Tai, Derek J.C., de Esch, Celine, Nuttle, Alexander, Temirov, Jamshid, Burnett, Lisa C., Rosenbaum, Michael, Zhang, Yiying, Ding, Li, Moresco, James J., Diedrich, Jolene K., Yates, John R., Tillman, Heather S., Leibel, Rudolph L., Talkowski, Michael E., Billadeau, Daniel D., Reiter, Lawrence T., Potts, Patrick Ryan
Publicado 2020

Massive clonal expansion of polycytotoxic skin and blood CD8(+) T cells in patients with toxic epidermal necrolysis patients

por Villani, Axel Patrice, Rozieres, Aurore, Bensaid, Benoît, Eriksson, Klara Kristin, Mosnier, Amandine, Albert, Floriane, Mutez, Virginie, Brassard, Océane, Baysal, Tugba, Tardieu, Mathilde, Allatif, Omran, Fusil, Floriane, Andrieu, Thibault, Jullien, Denis, Dubois, Valérie, Giannoli, Catherine, Gruffat, Henri, Pallardy, Marc, Cosset, François-Loïc, Nosbaum, Audrey, Kanagawa, Osami, Maryanski, Janet L., Yerly, Daniel, Nicolas, Jean-François, Vocanson, Marc
Publicado 2021

Automated Analysis of Risk Factors for Postictal Generalized EEG Suppression

por Zhao, Xiuhe, Vilella, Laura, Zhu, Liang, Rani, M. R. Sandhya, Hampson, Johnson P., Hampson, Jaison, Hupp, Norma J., Sainju, Rup K., Friedman, Daniel, Nei, Maromi, Scott, Catherine, Allen, Luke, Gehlbach, Brian K., Schuele, Stephan, Harper, Ronald M., Diehl, Beate, Bateman, Lisa M., Devinsky, Orrin, Richerson, George B., Zhang, Guo-Qiang, Lhatoo, Samden D., Lacuey, Nuria
Publicado 2021

Chromatin remodelling complex dosage modulates transcription factor function in heart development

por Takeuchi, Jun K., Lou, Xin, Alexander, Jeffrey M., Sugizaki, Hiroe, Delgado-Olguín, Paul, Holloway, Alisha K., Mori, Alessandro D., Wylie, John N., Munson, Chantilly, Zhu, Yonghong, Zhou, Yu-Qing, Yeh, Ru-Fang, Henkelman, R. Mark, Harvey, Richard P., Metzger, Daniel, Chambon, Pierre, Stainier, Didier Y. R., Pollard, Katherine S., Scott, Ian C., Bruneau, Benoit G.
Publicado 2011

Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1 mutated myelodysplasia

por Mian, Syed A, Philippe, Céline, Maniati, Eleni, Protopapa, Pantelitsa, Bergot, Tiffany, Piganeau, Marion, Nemkov, Travis, Bella, Doriana Di, Morales, Valle, Finch, Andrew J, D’Alessandro, Angelo, Bianchi, Katiuscia, Wang, Jun, Gallipoli, Paolo, Kordasti, Shahram, Kubasch, Anne Sophie, Cross, Michael, Platzbecker, Uwe, Wiseman, Daniel H, Bonnet, Dominique, Bernard, Delphine G, Gribben, John G, Rouault-Pierre, Kevin
Publicado 2023

Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine

por Spanjaard, Aldo, Shah, Ronak, de Groot, Daniël, Buoninfante, Olimpia Alessandra, Morris, Ben, Lieftink, Cor, Pritchard, Colin, Zürcher, Lisa M, Ormel, Shirley, Catsman, Joyce J I, de Korte-Grimmerink, Renske, Siteur, Bjørn, Proost, Natalie, Boadum, Terry, van de Ven, Marieke, Song, Ji-Ying, Kreft, Maaike, van den Berk, Paul C M, Beijersbergen, Roderick L, Jacobs, Heinz
Publicado 2022

Higher throughput drug screening for rare respiratory diseases: readthrough therapy in primary ciliary dyskinesia

por Lee, Dani Do Hyang, Cardinale, Daniela, Nigro, Ersilia, Butler, Colin R., Rutman, Andrew, Fassad, Mahmoud R., Hirst, Robert A., Moulding, Dale, Agrotis, Alexander, Forsythe, Elisabeth, Peckham, Daniel, Robson, Evie, Smith, Claire M., Somavarapu, Satyanarayana, Beales, Philip L., Hart, Stephen L., Janes, Sam M., Mitchison, Hannah M., Ketteler, Robin, Hynds, Robert E., O'Callaghan, Christopher
Publicado 2021

Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases

por Zhou, Danlei, Rudnicki, Michael, Chua, Gilbert T., Lawrance, Simon K., Zhou, Bi, Drew, Joanne L., Barbar-Smiley, Fatima, Armstrong, Taylor K., Hilt, Miranda E., Birmingham, Daniel J., Passler, Werner, Auletta, Jeffrey J., Bowden, Sasigarn A., Hoffman, Robert P., Wu, Yee Ling, Jarjour, Wael N., Mok, Chi Chiu, Ardoin, Stacy P., Lau, Yu Lung, Yu, Chack Yung
Publicado 2021