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61“…BACKGROUND: Leaf vein networks are critical to both the structure and function of leaves. …”
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62Logic minimization and rule extraction for identification of functional sites in molecular sequences“…BACKGROUND: Logic minimization is the application of algebraic axioms to a binary dataset with the purpose of reducing the number of digital variables and/or rules needed to express it. …”
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63por Sun, Qian, Muckatira, Sherin, Yuan, Lei, Ji, Shuiwang, Newfeld, Stuart, Kumar, Sudhir, Ye, Jieping“…The spatio-temporal gene expression patterns of Drosophila melanogaster can be visualized by in situ hybridization and documented as digital images. Automated and efficient tools for analyzing these expression images will provide biological insights into the gene functions, interactions, and networks. …”
Publicado 2013
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64por Aronoff-Spencer, Eliah, McComsey, Melanie, Chih, Ming-Yuan, Hubenko, Alexandra, Baker, Corey, Kim, John, Ahern, David K, Gibbons, Michael Christopher, Cafazzo, Joseph A, Nyakairu, Pia, Vanderpool, Robin C, Mullett, Timothy W, Hesse, Bradford W“…The codeveloped digital myPath app showed the highest perceived combined usability (mean 81.9, SD 15.2) compared with the current gold standard of distress management for patients with cancer, the paper-based National Comprehensive Cancer Network Distress Thermometer (mean 74.2, SD 15.8). …”
Publicado 2022
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65“…CONCLUSIONS: We found that CALIMA proved to be a robust and fast tool to analyze the data of experiments for the digital reconstruction of the neuronal cellular network while being able to process the analysis steps with minimal user input required and in a time efficient manner.…”
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66“…Next, we focused on gene expression based knowledge discovery studies such as transcription factor binding site analysis, pathway analysis, protein- protein interaction network analysis and gene enrichment analysis.…”
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67Publicado 2021“…Software packages were developed and open-sourced through the Python Package Index (PyPi) and the Comprehensive R Archive Network (CRAN). cgmquantify is integrated into the Digital Biomarker Discovery Pipeline and MD2K Cerebral Cortex. …”
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68Publicado 1993“…The degree of orientation appears to be dependent on cell-cell and cell-substrate adhesions. By performing digital optical sectioning microscopy on a highly spread NRK subclone, we show that actin filaments organize as a largely isotropic cortical meshwork in metaphase cells and convert into an anisotropic network shortly after anaphase onset, becoming more organized as cytokinesis proceeds. …”
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69“…Here, we present a novel projection pursuit recurrent neural network to identify functional mechanisms in the context of iterative supervised machine learning for discovery-based design optimization. …”
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70por Koo, Bon San, Lee, Jae Joon, Jung, Jae-Woo, Kang, Chang Ho, Joo, Kyung Bin, Kim, Tae-Hwan, Lee, Seunghun“…OBJECTIVE: This pilot study aimed to develop a deep learning model for grading the corners of the cervical and lumbar vertebral bodies for computer-aided detection of mSASSS in patients with ankylosing spondylitis (AS). METHODS: Digital radiographic examination of the spine was performed using Discovery XR656 (GE Healthcare) and Digital Diagnost (Philips). …”
Publicado 2022
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71por Wesołowski, Sergiusz, Lemmon, Gordon, Hernandez, Edgar J., Henrie, Alex, Miller, Thomas A., Weyhrauch, Derek, Puchalski, Michael D., Bray, Bruce E., Shah, Rashmee U., Deshmukh, Vikrant G., Delaney, Rebecca, Yost, H. Joseph, Eilbeck, Karen, Tristani-Firouzi, Martin, Yandell, MarkEnlace del recurso
Publicado 2022
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72“…The findings and insights of this study will facilitate the development of digital pathology in non-clinical research and improve the probability of success in drug discovery research.…”
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73por Kumar M V, Manoj, Patil, Jagadish, Shastry, K. Aditya, Darshan, Shiva, Sastry, Nanda Kumar Bidare, Moonesar, Immanuel Azaad, Atalla, Shadi, Almuraqab, Nasser, Rao, Ananth“…The open and flexible design allows users to access various digital materials. Extendable data/metadata format, scalable architecture for petabyte-scale federated discovery. …”
Publicado 2022
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75“…Genome sequences of marine streptomycetes are valuable for the discovery of useful enzymes and bioactive compounds by genome mining. …”
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76por Yao, Xinyue, Shen, Hong, Cao, Fukai, He, Hailan, Li, Boyu, Zhang, Haojun, Zhang, Xinduo, Li, Zhiguo“…We further constructed a protein-protein interaction (PPI) network of DEGs to identify the core genes. We used digital cytometry software CIBERSORTx to analyze the infiltration of immune cells in DN. …”
Publicado 2021
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77por Calzolari, Diego, Bruschi, Stefania, Coquin, Laurence, Schofield, Jennifer, Feala, Jacob D., Reed, John C., McCulloch, Andrew D., Paternostro, Giovanni“…Here we suggest a novel application of search algorithms—originally developed for digital communication—modified to optimize combinations of therapeutic interventions. …”
Publicado 2008
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78“…Trained solely on datasets for epithelial cells, the GAN can be extrapolated to other contractile cell types using only a single scaling factor. The digital TFM serves as a high-throughput tool for mapping out cellular forces of cell monolayers and paves the way toward data-driven discoveries in cell mechanobiology.…”
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79por Jiang, Xiaobo“…In addition, for the discovery and utilization of archive information, it is necessary to further explore and analyze the correlation between the contents of the archive data. …”
Publicado 2022
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80por Bordino, Ilaria, Battiston, Stefano, Caldarelli, Guido, Cristelli, Matthieu, Ukkonen, Antti, Weber, Ingmar“…We live in a computerized and networked society where many of our actions leave a digital trace and affect other people’s actions. …”
Publicado 2012
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