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61por Mansfield-Devine, Steve“…Two months ago, in this column, I predicted that the UK Government's Covid-19 tracing app was doomed to failure. …”
Publicado 2020
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62“…Using live cell imaging of the abdomen, two groups of larval muscles can be observed, doomed muscles that undergo histolysis and persistent muscles that are remodelled and survive into adulthood. …”
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63“…There has been concern that molecularly targeted therapy is doomed to failure, with resistant clones emerging in response to the Darwinian selective pressure of any drug treatment. …”
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64“…If we continue down the prim road path of fighting addiction to narcotics with narcotics, we are doomed to fail. This lesson can also have global interest.…”
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69por Ott, Douglas E.“…RESULTS: Ninety-five articles with 2,424 references were evaluated. There were 1,025 (1,025/2,424 = 42.3%) open access versus 1,399 (1,399/2,424 = 47.7%) paywall articles. …”
Publicado 2022
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70“…A keratoprosthesis or KPro is the only alternative to restore vision when corneal graft is a doomed failure. Although a number of KPros have been proposed, only two devices, Boston type-1 KPro and osteo-odonto-KPro, have came to the fore. …”
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71“…The myriads of technological advancements in dentistry in last two decades have led to a dramatic shift from conventional invasive procedures to more conservative biomimetic therapies. …”
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74“…Here we report that the hyphae of Streptomyces antibioticus die through an orderly process of internal cell dismantling that permits the doomed hyphae to be eliminated with minimum disruption of the colony architecture. …”
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75A model of muscle atrophy based on live microscopy of muscle remodelling in Drosophila metamorphosis“…In Drosophila melanogaster metamorphosis, larval abdominal muscles undergo two developmental fates. While a doomed population is eliminated by cell death, another persistent group is remodelled and survives into adulthood. …”
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76por Shrestha, Abhigan Babu, Khatroth, Sumalatha, Malreddy, Anannya, Issa, Farah Abdulkadir, Shrestha, Sajina, Shrestha, Shumneva“…The extensive impact of this rapidly spreading deadly virus doomed the health care systems with the unexpected wave wreaked havoc leading to a global health crisis. …”
Publicado 2022
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77por Thabane, Lehana, Ma, Jinhui, Chu, Rong, Cheng, Ji, Ismaila, Afisi, Rios, Lorena P, Robson, Reid, Thabane, Marroon, Giangregorio, Lora, Goldsmith, Charles H“…Conducting a pilot prior to the main study can enhance the likelihood of success of the main study and potentially help to avoid doomed main studies. The objective of this paper is to provide a detailed examination of the key aspects of pilot studies for phase III trials including: 1) the general reasons for conducting a pilot study; 2) the relationships between pilot studies, proof-of-concept studies, and adaptive designs; 3) the challenges of and misconceptions about pilot studies; 4) the criteria for evaluating the success of a pilot study; 5) frequently asked questions about pilot studies; 7) some ethical aspects related to pilot studies; and 8) some suggestions on how to report the results of pilot investigations using the CONSORT format.…”
Publicado 2010
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78por Ait Aoudia, Fayçal, Gautier, Matthieu, Magno, Michele, Berder, Olivier, Benini, Luca“…However, as the batteries can only store a finite amount of energy, the network is still doomed to die, and changing the batteries is not always possible. …”
Publicado 2018
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79por Hirsiger, Stefanie, Betz, Michael, Stafylakis, Dimitrios, Götschi, Tobias, Lew, Daniel, Uçkay, Ilker“…Some authors claim that lacking the exchange of mobile prosthetic parts is doomed to failure, while others regard it as optional. …”
Publicado 2019
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80por Meijaard, Erik, Ni’matullah, Safwanah, Dennis, Rona, Sherman, Julie, Onrizal, Wich, Serge A.“…It is restricted to an area of about 1,000 km(2) of upland forest where fewer than 800 animals survive in three declining subpopulations. …”
Publicado 2021
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