11β-Hydroxysteroid dehydrogenase type 1 contributes to the regulation of 7-oxysterol levels in the arterial wall through the inter-conversion of 7-ketocholesterol and 7β-hydroxycho...

por Mitić, Tijana, Andrew, Ruth, Walker, Brian R., Hadoke, Patrick W.F.
Publicado 2013

A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction

por Watterson, Steven, Guerriero, Maria Luisa, Blanc, Mathieu, Mazein, Alexander, Loewe, Laurence, Robertson, Kevin A., Gibbs, Holly, Shui, Guanghou, Wenk, Markus R., Hillston, Jane, Ghazal, Peter
Publicado 2013

Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites

por Lebedeva, Natalia A., Rechkunova, Nadejda I., El-Khamisy, Sherif F., Lavrik, Olga I.
Publicado 2012

Pleiotropic regulation of mitochondrial function by adipose triglyceride lipase-mediated lipolysis()

por Kratky, Dagmar, Obrowsky, Sascha, Kolb, Dagmar, Radovic, Branislav
Publicado 2014

A novel estrogen-regulated avian apolipoprotein()

por Nikolay, Birgit, Plieschnig, Julia A., Šubik, Desiree, Schneider, Jeannine D., Schneider, Wolfgang J., Hermann, Marcela
Publicado 2013

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

por Deng, Xianming, Elkins, Jonathan M., Zhang, Jinwei, Yang, Qingkai, Erazo, Tatiana, Gomez, Nestor, Choi, Hwan Geun, Wang, Jinhua, Dzamko, Nicolas, Lee, Jiing-Dwan, Sim, Taebo, Kim, NamDoo, Alessi, Dario R., Lizcano, Jose M., Knapp, Stefan, Gray, Nathanael S.
Publicado 2013

Mitochondrial translation initiation machinery: Conservation and diversification()

por Kuzmenko, Anton, Atkinson, Gemma C., Levitskii, Sergey, Zenkin, Nikolay, Tenson, Tanel, Hauryliuk, Vasili, Kamenski, Piotr
Publicado 2014

Pathophysiology of X-linked adrenoleukodystrophy()

por Berger, J., Forss-Petter, S., Eichler, F.S.
Publicado 2014

Expression of microsomal triglyceride transfer protein in lipoprotein-synthesizing tissues of the developing chicken embryo()

por Eresheim, Christine, Plieschnig, Julia, Ivessa, N. Erwin, Schneider, Wolfgang J., Hermann, Marcela
Publicado 2014

Synthesis and evaluation of imidazole-4,5- and pyrazine-2,3-dicarboxamides targeting dengue and yellow fever virus()

por Saudi, Milind, Zmurko, Joanna, Kaptein, Suzanne, Rozenski, Jef, Neyts, Johan, Van Aerschot, Arthur
Publicado 2014

Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors

por Dražić, Tonko, Molčanov, Krešimir, Sachdev, Vinay, Malnar, Martina, Hećimović, Silva, Patankar, Jay V., Obrowsky, Sascha, Levak-Frank, Sanja, Habuš, Ivan, Kratky, Dagmar
Publicado 2014

Biochemical evaluation of virtual screening methods reveals a cell-active inhibitor of the cancer-promoting phosphatases of regenerating liver

por Hoeger, Birgit, Diether, Maren, Ballester, Pedro J., Köhn, Maja
Publicado 2014

Comparative biochemical analysis of three members of the Schistosoma mansoni TAL family: Differences in ion and drug binding properties

por Thomas, Charlotte M., Fitzsimmons, Colin M., Dunne, David W., Timson, David J.
Publicado 2015

Are stressful life events causally related to the severity of obsessive-compulsive symptoms? A monozygotic twin difference study

por Vidal-Ribas, P., Stringaris, A., Rück, C., Serlachius, E., Lichtenstein, P., Mataix-Cols, D.
Publicado 2015

The role of TDP1 and APTX in mitochondrial DNA repair

por Meagher, Martin, Lightowlers, Robert N.
Publicado 2014

Taming molecular flexibility to tackle rare diseases

por Cubellis, Maria Vittoria, Baaden, Marc, Andreotti, Giuseppina
Publicado 2015

Prospective performance evaluation of selected common virtual screening tools. Case study: Cyclooxygenase (COX) 1 and 2

por Kaserer, Teresa, Temml, Veronika, Kutil, Zsofia, Vanek, Tomas, Landa, Premysl, Schuster, Daniela
Publicado 2015

Economic risk coding by single neurons in the orbitofrontal cortex

por O’Neill, Martin, Schultz, Wolfram
Publicado 2015

Characterization of reward and effort mechanisms in apathy

por Bonnelle, Valerie, Veromann, Kai-Riin, Burnett Heyes, Stephanie, Lo Sterzo, Elena, Manohar, Sanjay, Husain, Masud
Publicado 2015

Metronidazole-triazole conjugates: Activity against Clostridium difficile and parasites

por Jarrad, Angie M., Karoli, Tomislav, Debnath, Anjan, Tay, Chin Yen, Huang, Johnny X., Kaeslin, Geraldine, Elliott, Alysha G., Miyamoto, Yukiko, Ramu, Soumya, Kavanagh, Angela M., Zuegg, Johannes, Eckmann, Lars, Blaskovich, Mark A.T., Cooper, Matthew A.
Publicado 2015