Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation

por Bauer, Claudia S., Webster, Christopher P., Shaw, Allan C., Kok, Jannigje R., Castelli, Lydia M., Lin, Ya-Hui, Smith, Emma F., Illanes-Álvarez, Francisco, Higginbottom, Adrian, Shaw, Pamela J., Azzouz, Mimoun, Ferraiuolo, Laura, Hautbergue, Guillaume M., Grierson, Andrew J., De Vos, Kurt J.
Publicado 2022

Diagnosis of COVID-19 by analysis of breath with gas chromatography-ion mobility spectrometry - a feasibility study

por Ruszkiewicz, Dorota M, Sanders, Daniel, O'Brien, Rachel, Hempel, Frederik, Reed, Matthew J, Riepe, Ansgar C, Bailie, Kenneth, Brodrick, Emma, Darnley, Kareen, Ellerkmann, Richard, Mueller, Oliver, Skarysz, Angelika, Truss, Michael, Wortelmann, Thomas, Yordanov, Simeon, Thomas, C.L.Paul, Schaaf, Bernhard, Eddleston, Michael
Publicado 2020

Colorectal cancer development is affected by the ECM molecule EMILIN-2 hinging on macrophage polarization via the TLR-4/MyD88 pathway

por Andreuzzi, Eva, Fejza, Albina, Polano, Maurizio, Poletto, Evelina, Camicia, Lucrezia, Carobolante, Greta, Tarticchio, Giulia, Todaro, Federico, Di Carlo, Emma, Scarpa, Melania, Scarpa, Marco, Paulitti, Alice, Capuano, Alessandra, Canzonieri, Vincenzo, Maiero, Stefania, Fornasarig, Mara, Cannizzaro, Renato, Doliana, Roberto, Colombatti, Alfonso, Spessotto, Paola, Mongiat, Maurizio
Publicado 2022

Plasma Cell-free DNA Concentration and Outcomes from Taxane Therapy in Metastatic Castration-resistant Prostate Cancer from Two Phase III Trials (FIRSTANA and PROSELICA)

por Mehra, Niven, Dolling, David, Sumanasuriya, Semini, Christova, Rossitza, Pope, Lorna, Carreira, Suzanne, Seed, George, Yuan, Wei, Goodall, Jane, Hall, Emma, Flohr, Penny, Boysen, Gunther, Bianchini, Diletta, Sartor, Oliver, Eisenberger, Mario A., Fizazi, Karim, Oudard, Stephane, Chadjaa, Mustapha, Macé, Sandrine, de Bono, Johann S.
Publicado 2018

Community prevalence of SARS-CoV-2 in England from April to November, 2020: results from the ONS Coronavirus Infection Survey

por Pouwels, Koen B, House, Thomas, Pritchard, Emma, Robotham, Julie V, Birrell, Paul J, Gelman, Andrew, Vihta, Karina-Doris, Bowers, Nikola, Boreham, Ian, Thomas, Heledd, Lewis, James, Bell, Iain, Bell, John I, Newton, John N, Farrar, Jeremy, Diamond, Ian, Benton, Pete, Walker, Ann Sarah
Publicado 2021

Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis

por Amin, Abdulbasit, Badenes, Marina, Tüshaus, Johanna, de Carvalho, Érika, Burbridge, Emma, Faísca, Pedro, Trávníčková, Květa, Barros, André, Carobbio, Stefania, Domingos, Pedro M., Vidal-Puig, Antonio, Moita, Luís F., Maguire, Sarah, Stříšovský, Kvido, Ortega, Francisco J., Fernández-Real, José Manuel, Lichtenthaler, Stefan F., Adrain, Colin
Publicado 2023

Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice

por Sedhom, Mamdouh A K, Pichery, Mélanie, Murdoch, Jenna R, Foligné, Benoit, Ortega, Nathalie, Normand, Sylvain, Mertz, Kirsten, Sanmugalingam, Devika, Brault, Lea, Grandjean, Teddy, Lefrancais, Emma, Fallon, Padraic G, Quesniaux, Valérie, Peyrin-Biroulet, Laurent, Cathomas, Gieri, Junt, Tobias, Chamaillard, Mathias, Girard, Jean-Philippe, Ryffel, Bernhard
Publicado 2013

WHO's Therapeutics and COVID-19 Living Guideline on mAbs needs to be reassessed

por Wu, Mary Y, Carr, Edward J, Harvey, Ruth, Mears, Harriet V, Kjaer, Svend, Townsley, Hermaleigh, Hobbs, Agnieszka, Ragno, Martina, Herman, Lou S, Adams, Lorin, Gamblin, Steve, Howell, Michael, Beale, Rupert, Brown, Michael, Williams, Bryan, Gandhi, Sonia, Swanton, Charles, Wall, Emma C, Bauer, David L V
Publicado 2023

Dual targeting of p53 and c-Myc selectively eliminates leukaemic stem cells

por Abraham, Sheela A, Hopcroft, Lisa EM, Carrick, Emma, Drotar, Mark E, Dunn, Karen, Williamson, Andrew JK, Korfi, Koorosh, Baquero, Pablo, Park, Laura E, Scott, Mary T, Pellicano, Francesca, Pierce, Andrew, Copland, Mhairi, Nourse, Craig, Grimmond, Sean M, Vetrie, David, Whetton, Anthony D, Holyoake, Tessa L
Publicado 2016

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

por Gambin, Yann, Ariotti, Nicholas, McMahon, Kerrie-Ann, Bastiani, Michele, Sierecki, Emma, Kovtun, Oleksiy, Polinkovsky, Mark E, Magenau, Astrid, Jung, WooRam, Okano, Satomi, Zhou, Yong, Leneva, Natalya, Mureev, Sergey, Johnston, Wayne, Gaus, Katharina, Hancock, John F, Collins, Brett M, Alexandrov, Kirill, Parton, Robert G
Publicado 2014

Lrig2 and Hpse2, mutated in urofacial syndrome, pattern nerves in the urinary bladder

por Roberts, Neil A., Hilton, Emma N., Lopes, Filipa M., Singh, Subir, Randles, Michael J., Gardiner, Natalie J., Chopra, Karl, Coletta, Riccardo, Bajwa, Zunera, Hall, Robert J., Yue, Wyatt W., Schaefer, Franz, Weber, Stefanie, Henriksson, Roger, Stuart, Helen M., Hedman, Håkan, Newman, William G., Woolf, Adrian S.
Publicado 2019

Employing Molecular Phylodynamic Methods to Identify and Forecast HIV Transmission Clusters in Public Health Settings: A Qualitative Study

por Rich, Shannan N., Richards, Veronica L., Mavian, Carla N., Switzer, William M., Rife Magalis, Brittany, Poschman, Karalee, Geary, Shana, Broadway, Steven E., Bennett, Spencer B., Blanton, Jason, Leitner, Thomas, Boatwright, J. Lucas, Stetten, Nichole E., Cook, Robert L., Spencer, Emma C., Salemi, Marco, Prosperi, Mattia
Publicado 2020

Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction

por Ramos, M Ines Pascoal, Tian, Linjie, de Ruiter, Emma J, Song, Chang, Paucarmayta, Ana, Singh, Akashdip, Elshof, Eline, Vijver, Saskia V, Shaik, Jahangheer, Bosiacki, Jason, Cusumano, Zachary, Jensen, Christina, Willumsen, Nicholas, Karsdal, Morten A, Liu, Linda, Langermann, Sol, Willems, Stefan, Flies, Dallas, Meyaard, Linde
Publicado 2021

A population of naive‐like CD4(+) T cells stably polarized to the T(H)1 lineage

por Lo, Jonathan W., de Mucha, Maria Vila, Henderson, Stephen, Roberts, Luke B., Constable, Laura E., Garrido‐Mesa, Natividad, Hertweck, Arnulf, Stolarczyk, Emilie, Houlder, Emma L., Jackson, Ian, MacDonald, Andrew S., Powell, Nick, Neves, Joana F., Howard, Jane K., Jenner, Richard G., Lord, Graham M.
Publicado 2022

Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis

por Ikeh, Mélanie A. C., Kastora, Stavroula L., Day, Alison M., Herrero-de-Dios, Carmen M., Tarrant, Emma, Waldron, Kevin J., Banks, A. Peter, Bain, Judith M., Lydall, David, Veal, Elizabeth A., MacCallum, Donna M., Erwig, Lars P., Brown, Alistair J. P., Quinn, Janet
Publicado 2016

A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke

por Eyford, Brett A., Singh, Chaahat S. B., Abraham, Thomas, Munro, Lonna, Choi, Kyung Bok, Hill, Tracy, Hildebrandt, Rhonda, Welch, Ian, Vitalis, Timothy Z., Gabathuler, Reinhard, Gordon, Jacob A., Adomat, Hans, Guns, Emma S.T., Lu, Chieh-Ju, Pfeifer, Cheryl G., Tian, Mei Mei, Jefferies, Wilfred A.
Publicado 2021

Increased mitochondrial proline metabolism sustains proliferation and survival of colorectal cancer cells

por Alaqbi, Saif Sattar, Burke, Lynsey, Guterman, Inna, Green, Caleb, West, Kevin, Palacios-Gallego, Raquel, Cai, Hong, Alexandrou, Constantinos, Myint, Ni Ni Moe, Parrott, Emma, Howells, Lynne M., Higgins, Jennifer A., Jones, Donald J. L., Singh, Rajinder, Britton, Robert G., Tufarelli, Cristina, Thomas, Anne, Rufini, Alessandro
Publicado 2022

SARS-CoV-2 Assays To Detect Functional Antibody Responses That Block ACE2 Recognition in Vaccinated Animals and Infected Patients

por Walker, Susanne N., Chokkalingam, Neethu, Reuschel, Emma L., Purwar, Mansi, Xu, Ziyang, Gary, Ebony N., Kim, Kevin Y., Helble, Michaela, Schultheis, Katherine, Walters, Jewell, Ramos, Stephanie, Muthumani, Kar, Smith, Trevor R. F., Broderick, Kate E., Tebas, Pablo, Patel, Ami, Weiner, David B., Kulp, Daniel W.
Publicado 2020

A Phase Ib/II Trial of Combined BRAF and EGFR Inhibition in BRAF V600E Positive Metastatic Colorectal Cancer and Other Cancers: The EVICT (Erlotinib and Vemurafenib In Combination...

por Tan, Lavinia, Tran, Ben, Tie, Jeanne, Markman, Ben, Ananda, Sumi, Tebbutt, Niall C., Michael, Michael, Link, Emma, Wong, Stephen Q., Chandrashekar, Sushma, Guinto, Jerick, Ritchie, David, Koldej, Rachel, Solomon, Benjamin J., McArthur, Grant A., Hicks, Rodney J., Gibbs, Peter, Dawson, Sarah-Jane, Desai, Jayesh
Publicado 2023

Identification of a neuronal transcription factor network involved in medulloblastoma development

por Łastowska, Maria, Al-Afghani, Hani, Al-Balool, Haya H, Sheth, Harsh, Mercer, Emma, Coxhead, Jonathan M, Redfern, Chris PF, Peters, Heiko, Burt, Alastair D, Santibanez-Koref, Mauro, Bacon, Chris M, Chesler, Louis, Rust, Alistair G, Adams, David J, Williamson, Daniel, Clifford, Steven C, Jackson, Michael S
Publicado 2013