A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope

por VanBlargan, Laura A., Adams, Lucas J., Liu, Zhuoming, Chen, Rita E., Gilchuk, Pavlo, Raju, Saravanan, Smith, Brittany K., Zhao, Haiyan, Case, James Brett, Winkler, Emma S., Whitener, Bradley M., Droit, Lindsay, Aziati, Ishmael D., Bricker, Traci L., Joshi, Astha, Shi, Pei-Yong, Creanga, Adrian, Pegu, Amarendra, Handley, Scott A., Wang, David, Boon, Adrianus C.M., Crowe, James E., Whelan, Sean P.J., Fremont, Daved H., Diamond, Michael S.
Publicado 2021

Pediatric Surgical Waitlist in Low Middle Income Countries During the COVID-19 Pandemic

por Klazura, Greg, Park, Paul, Yap, Ava, Laverde, Ruth, Bryce, Emma, Cheung, Maija, Bioh, Ernestina, Kisa, Phyllis, Kakembo, Nasser, Ugazzi, Michele, Situma, Martin, Borgstein, Eric, Derbew, Miliard, Negash, Samuel, Tadesse, Amezene, Bvulani, Bruce, Ki, Bertille, Toussaint, Tapsoba, Bokhary, Zaitun, Philipo, Godfrey Sama, Ameh, Emmanuel, Mulewa, Mulenga, Mwansa, Jonathan, Onah, Ifeanyichukwu, Amado, Vanda, De Ugarte, Daniel, Massaga, Fabian, Byabato, Samwel, Adeyemo, Wasiu Lanre, Ogunlewe, Olugbemiga, Nandi, Bip, Ozgediz, Doruk
Publicado 2023

Pre-clinical validation of a pan-cancer CAR-T cell immunotherapy targeting nfP2X7

por Bandara, Veronika, Foeng, Jade, Gundsambuu, Batjargal, Norton, Todd S., Napoli, Silvana, McPeake, Dylan J., Tyllis, Timona S., Rohani-Rad, Elaheh, Abbott, Caitlin, Mills, Stuart J., Tan, Lih Y., Thompson, Emma J., Willet, Vasiliki M., Nikitaras, Victoria J., Zheng, Jieren, Comerford, Iain, Johnson, Adam, Coombs, Justin, Oehler, Martin K., Ricciardelli, Carmela, Cowin, Allison J., Bonder, Claudine S., Jensen, Michael, Sadlon, Timothy J., McColl, Shaun R., Barry, Simon C.
Publicado 2023

Adults with RRM2B-related mitochondrial disease have distinct clinical and molecular characteristics

por Pitceathly, Robert D. S., Smith, Conrad, Fratter, Carl, Alston, Charlotte L., He, Langping, Craig, Kate, Blakely, Emma L., Evans, Julie C., Taylor, John, Shabbir, Zarfishan, Deschauer, Marcus, Pohl, Ute, Roberts, Mark E., Jackson, Matthew C., Halfpenny, Christopher A., Turnpenny, Peter D., Lunt, Peter W., Hanna, Michael G., Schaefer, Andrew M., McFarland, Robert, Horvath, Rita, Chinnery, Patrick F., Turnbull, Douglass M., Poulton, Joanna, Taylor, Robert W., Gorman, Gráinne S.
Publicado 2012

Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model

por Proud, Pamela C., Tsitoura, Daphne, Watson, Robert J., Chua, Brendon Y., Aram, Marilyn J., Bewley, Kevin R., Cavell, Breeze E., Cobb, Rebecca, Dowall, Stuart, Fotheringham, Susan A., Ho, Catherine M.K., Lucas, Vanessa, Ngabo, Didier, Rayner, Emma, Ryan, Kathryn A., Slack, Gillian S., Thomas, Stephen, Wand, Nadina I., Yeates, Paul, Demaison, Christophe, Zeng, Weiguang, Holmes, Ian, Jackson, David C., Bartlett, Nathan W., Mercuri, Francesca, Carroll, Miles W.
Publicado 2020

Evaluating the cost implications of integrating SARS-CoV-2 genome sequencing for infection prevention and control investigation of nosocomial transmission within hospitals

por Panca, Monica, Blackstone, James, Stirrup, Oliver, Cutino-Moguel, Maria-Teresa, Thomson, Emma, Peters, Christine, Snell, Luke B., Nebbia, Gaia, Holmes, Alison, Chawla, Anu, Machin, Nicholas, Taha, Yusri, Mahungu, Tabitha, Saluja, Tranprit, de Silva, Thushan I., Saeed, Kordo, Pope, Cassie, Shin, Gee Yen, Williams, Rachel, Darby, Alistair, Smith, Darren L., Loose, Matthew, Robson, Samuel C., Laing, Kenneth, Partridge, David G., Price, James R., Breuer, Judith
Publicado 2023

Epidemiology and genetic variability of respiratory syncytial virus in Portugal, 2014–2018

por Sáez-López, Emma, Cristóvão, Paula, Costa, Inês, Pechirra, Pedro, Conde, Patrícia, Guiomar, Raquel, Peres, Maria João, Viseu, Regina, Lopes, Paulo, Soares, Vânia, Vale, Fátima, Fonseca, Patricia, Freitas, Ludivina, Alves, Jose, Pessanha, Maria Ana, Toscano, Cristina, Mota-Vieira, Luísa, Veloso, Rita Cabral, Côrte-Real, Rita, Branquinho, Paula, Pereira‑Vaz, João, Rodrigues, Fernando, Cunha, Mário, Martins, Luís, Mota, Paula, Couto, Ana Rita, Bruges-Armas, Jácome, Almeida, Sofia, Rodrigues, Débora
Publicado 2019

Assessment of immunological anti‐platelet factor 4 antibodies for vaccine‐induced thrombotic thrombocytopenia (VITT) in a large Australian cohort: A multicenter study comprising 12...

por Favaloro, Emmanuel J., Clifford, Joanne, Leitinger, Emma, Parker, Michael, Sung, Pauline, Chunilal, Sanjeev, Tran, Huyen, Kershaw, Geoffrey, Fu, Suki, Passam, Freda, Ahuja, Monica, Ho, Shir Jing, Duncan, Elizabeth, Yacoub, Olivia, Tan, Chee Wee, Kaminskis, Lisa, Modica, Natasha, Pepperell, Dominic, Ballard, Leanne, Clarke, Lisa, Lee, Christine S.M., Gardiner, Elizabeth E., Young‐Ill Choi, Philip, Tohidi‐Esfahani, Ibrahim, Bird, Robert, Brighton, Timothy, Chen, Vivien M.
Publicado 2022

Epilepsy due to PNPO mutations: genotype, environment and treatment affect presentation and outcome

por Mills, Philippa B., Camuzeaux, Stephane S.M., Footitt, Emma J., Mills, Kevin A., Gissen, Paul, Fisher, Laura, Das, Krishna B., Varadkar, Sophia M., Zuberi, Sameer, McWilliam, Robert, Stödberg, Tommy, Plecko, Barbara, Baumgartner, Matthias R., Maier, Oliver, Calvert, Sophie, Riney, Kate, Wolf, Nicole I., Livingston, John H., Bala, Pronab, Morel, Chantal F., Feillet, François, Raimondi, Francesco, Del Giudice, Ennio, Chong, W. Kling, Pitt, Matthew, Clayton, Peter T.
Publicado 2014

Daily testing for contacts of individuals with SARS-CoV-2 infection and attendance and SARS-CoV-2 transmission in English secondary schools and colleges: an open-label, cluster-ran...

por Young, Bernadette C, Eyre, David W, Kendrick, Saroj, White, Chris, Smith, Sylvester, Beveridge, George, Nonnenmacher, Toby, Ichofu, Fegor, Hillier, Joseph, Oakley, Sarah, Diamond, Ian, Rourke, Emma, Dawe, Fiona, Day, Ieuan, Davies, Lisa, Staite, Paul, Lacey, Andrea, McCrae, James, Jones, Ffion, Kelly, Joseph, Bankiewicz, Urszula, Tunkel, Sarah, Ovens, Richard, Chapman, David, Bhalla, Vineta, Marks, Peter, Hicks, Nick, Fowler, Tom, Hopkins, Susan, Yardley, Lucy, Peto, Tim E A
Publicado 2021

Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer

por Fendler, Annika, Shepherd, Scott T C, Au, Lewis, Wu, Mary, Harvey, Ruth, Schmitt, Andreas M, Tippu, Zayd, Shum, Benjamin, Farag, Sheima, Rogiers, Aljosja, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Deng, Daqi, Kjaer, Svend, Song, Ok-Ryul, Queval, Christophe, Kavanagh, Caitlin, Wall, Emma C, Carr, Edward J, Caidan, Simon, Gavrielides, Mike, MacRae, James I, Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O'Flaherty, Molly, Shea, Robyn L, Gardner, Gail, Murray, Darren, Yousaf, Nadia, Jhanji, Shaman, Tatham, Kate, Cunningham, David, Van As, Nicholas, Young, Kate, Furness, Andrew J S, Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L V, Kassiotis, George, Howell, Michael, Nicholson, Emma, Walker, Susanna, Larkin, James, Turajlic, Samra
Publicado 2022

Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits

por Zhou, Hang, Sealock, Julia M., Sanchez-Roige, Sandra, Clarke, Toni-Kim, Levey, Daniel F., Cheng, Zhongshan, Li, Boyang, Polimanti, Renato, Kember, Rachel L., Smith, Rachel Vickers, Thygesen, Johan H., Morgan, Marsha Y., Atkinson, Stephen R., Thursz, Mark R., Nyegaard, Mette, Mattheisen, Manuel, Børglum, Anders D., Johnson, Emma C., Justice, Amy C., Palmer, Abraham A., McQuillin, Andrew, Davis, Lea K., Edenberg, Howard J., Agrawal, Arpana, Kranzler, Henry R., Gelernter, Joel
Publicado 2020

Scientific consensus on the COVID-19 pandemic: we need to act now

por Alwan, Nisreen A, Burgess, Rochelle Ann, Ashworth, Simon, Beale, Rupert, Bhadelia, Nahid, Bogaert, Debby, Dowd, Jennifer, Eckerle, Isabella, Goldman, Lynn R, Greenhalgh, Trisha, Gurdasani, Deepti, Hamdy, Adam, Hanage, William P, Hodcroft, Emma B, Hyde, Zoë, Kellam, Paul, Kelly-Irving, Michelle, Krammer, Florian, Lipsitch, Marc, McNally, Alan, McKee, Martin, Nouri, Ali, Pimenta, Dominic, Priesemann, Viola, Rutter, Harry, Silver, Joshua, Sridhar, Devi, Swanton, Charles, Walensky, Rochelle P, Yamey, Gavin, Ziauddeen, Hisham
Publicado 2020

Effects of COVID -19 pandemic and lockdown on people with multiple system atrophy participating in a therapeutic education program

por Cámara, Ana, Compta, Yaroslau, Pérez-Soriano, Alexandra, Montagut, Núria, Baixauli, Montserrat, Maragall, Laura, Ludeña, Emma, Lopez de los Reyes, Juan Carlos, Peri-Cusi, Lluís, Fernández, Noemí, Villote, Susana, Ahuir, Maribel, Grau, Anna, Caballol, Núria, Buongiorno, Mariateresa, Pont-Sunyer, Claustre, Puente, Víctor, Giraldo, Darly M., de Fabregues, Oriol, Garrido, Alícia, Navarro-Otano, Judith, Painous, Cèlia, Sánchez-Gómez, Almudena, Muñoz, Esteban, Zaro, Idoia, Obiang, Donina, Valldeoriola, Francesc, Lombraña, María, Martí, María-José
Publicado 2021

KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation

por Pearce, Laura R., Atanassova, Neli, Banton, Matthew C., Bottomley, Bill, van der Klaauw, Agatha A., Revelli, Jean-Pierre, Hendricks, Audrey, Keogh, Julia M., Henning, Elana, Doree, Deon, Jeter-Jones, Sabrina, Garg, Sumedha, Bochukova, Elena G., Bounds, Rebecca, Ashford, Sofie, Gayton, Emma, Hindmarsh, Peter C., Shield, Julian P.H., Crowne, Elizabeth, Barford, David, Wareham, Nick J., O’Rahilly, Stephen, Murphy, Michael P., Powell, David R., Barroso, Ines, Farooqi, I. Sadaf
Publicado 2013

A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans

por Edwards, Sarah C., Sutton, Caroline E., Ladell, Kristin, Grant, Emma J., McLaren, James E., Roche, Fiona, Dash, Pradyot, Apiwattanakul, Nopporn, Awad, Walid, Miners, Kelly L., Lalor, Stephen J., Ribot, Julie C., Baik, Song, Moran, Barry, McGinley, Aoife, Pivorunas, Valerie, Dowding, Lori, Macoritto, Michael, Paez-Cortez, Jesus, Slavin, Anthony, Anderson, Graham, Silva-Santos, Bruno, Hokamp, Karsten, Price, David A., Thomas, Paul G., McLoughlin, Rachel M., Mills, Kingston H.G.
Publicado 2020

SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits

por Hautbergue, Guillaume M., Castelli, Lydia M., Ferraiuolo, Laura, Sanchez-Martinez, Alvaro, Cooper-Knock, Johnathan, Higginbottom, Adrian, Lin, Ya-Hui, Bauer, Claudia S., Dodd, Jennifer E., Myszczynska, Monika A., Alam, Sarah M., Garneret, Pierre, Chandran, Jayanth S., Karyka, Evangelia, Stopford, Matthew J., Smith, Emma F., Kirby, Janine, Meyer, Kathrin, Kaspar, Brian K., Isaacs, Adrian M., El-Khamisy, Sherif F., De Vos, Kurt J., Ning, Ke, Azzouz, Mimoun, Whitworth, Alexander J., Shaw, Pamela J.
Publicado 2017

DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport

por Hartill, Verity L, van de Hoek, Glenn, Patel, Mitali P, Little, Rosie, Watson, Christopher M, Berry, Ian R, Shoemark, Amelia, Abdelmottaleb, Dina, Parkes, Emma, Bacchelli, Chiara, Szymanska, Katarzyna, Knoers, Nine V, Scambler, Peter J, Ueffing, Marius, Boldt, Karsten, Yates, Robert, Winyard, Paul J, Adler, Beryl, Moya, Eduardo, Hattingh, Louise, Shenoy, Anil, Hogg, Claire, Sheridan, Eamonn, Roepman, Ronald, Norris, Dominic, Mitchison, Hannah M, Giles, Rachel H, Johnson, Colin A
Publicado 2018

Highly Sensitive Lineage Discrimination of SARS-CoV-2 Variants through Allele-Specific Probe PCR

por Ratcliff, Jeremy, Al-Beidh, Farah, Bibi, Sagida, Bonsall, David, Costa Clemens, Sue Ann, Estcourt, Lise, Evans, Amy, Fish, Matthew, Folegatti, Pedro M., Gordon, Anthony C., Jay, Cecilia, Jennings, Aislinn, Laing, Emma, Lambe, Teresa, MacIntyre-Cockett, George, Menon, David, Mouncey, Paul R., Nguyen, Dung, Pollard, Andrew J., Ramasamy, Maheshi N., Roberts, David J., Rowan, Kathryn M., Rynne, Jennifer, Shankar-Hari, Manu, Williams, Sarah, Harvala, Heli, Golubchik, Tanya, Simmonds, Peter
Publicado 2022

Oxidative stress and life histories: unresolved issues and current needs

por Speakman, John R., Blount, Jonathan D., Bronikowski, Anne M., Buffenstein, Rochelle, Isaksson, Caroline, Kirkwood, Tom B. L., Monaghan, Pat, Ozanne, Susan E., Beaulieu, Michaël, Briga, Michael, Carr, Sarah K., Christensen, Louise L., Cochemé, Helena M., Cram, Dominic L., Dantzer, Ben, Harper, Jim M., Jurk, Diana, King, Annette, Noguera, Jose C., Salin, Karine, Sild, Elin, Simons, Mirre J. P., Smith, Shona, Stier, Antoine, Tobler, Michael, Vitikainen, Emma, Peaker, Malcolm, Selman, Colin
Publicado 2015