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721“…Twelve lactating cattle × yak hybrids (B. taurus × B. grunniens) were investigated on five experimental pastures (Sites 1–5), following an up- and downward transhumance route (3,200, 4,000, 4,500, 4,000 and 2,600 m a.s.l.). …”
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722por Wilson, Ian M., Vucic, Emily A., Enfield, Katey S.S., Thu, Kelsie L., Zhang, Yu-An, Chari, Raj, Lockwood, William W., Radulovich, Niki, Starczynowski, Daniel T., Banáth, Judit P., Zhang, May, Pusic, Andrea, Fuller, Megan, Lonergan, Kim M., Rowbotham, David, Yee, John, English, John C., Buys, Timon P.H., Selamat, Suhaida A., Laird-Offringa, Ite A., Liu, Pengyuan, Anderson, Marshall, You, Ming, Tsao, Ming-Sound, Brown, Carolyn J., Bennewith, Kevin L., MacAulay, Calum E., Karsan, Aly, Gazdar, Adi F., Lam, Stephen, Lam, Wan L.“…By surveying lung tumor genomes for genes concomitantly inactivated within individual tumors by multiple mechanisms, and by the frequency of disruption in tumors across multiple cohorts, we have identified a putative lung cancer TSG, Eyes Absent 4 (EYA4). EYA4 is frequently and concomitantly deleted, hypermethylated and underexpressed in multiple independent lung tumor data sets, in both major NSCLC subtypes, and in the earliest stages of lung cancer. …”
Publicado 2013
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723por Niu, Qingli, Liu, Zhijie, Yu, Peifa, Yang, Jifei, Abdallah, Mirza Omar, Guan, Guiquan, Liu, Guangyuan, Luo, Jianxun, Yin, Hong“…METHODS: A total of 646 blood specimens from cattle, dairy cattle and yaks from 14 provinces were collected and tested for the presence of the three Babesia species via a specific nested PCR assay based on the rap-1 and ama-1 genes. …”
Publicado 2015
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724“…Although papillomaviruses (PVs) have been widely reported in vertebrates, there have been only a few PV reports in yaks (Bos grunniens). In 2012, Bam et al. reported bovine papillomavirus type 1 (BPV-1) and BPV-2 associated with cutaneous papillomatosis in yaks, which provided genomic and pathology information for yak PVs. …”
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725“…In this study, 69 lactobacilli isolated from Tibetan Qula, a raw yak milk cheese, were screened for their potential use as probiotics. …”
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726por Cao, Lu, Tang, Yingzhi, Quan, Zhenzhen, Zhang, Zhe, Oliver, Stephen G., Zhang, Nianshu“…Concurrent overexpression of GSY2 and TSL1 or supplementation of trehalose to the growth medium ameliorates the severe CLS defects displayed by the signaling mutants (rim15Δyak1Δ or rim15Δmck1Δ). Furthermore, we reveal that the levels of intracellular reactive oxygen species are cooperatively controlled by Yak1, Rim15 and Mck1, and the three kinases mediate the TOR1-regulated accumulation of storage carbohydrates and CLS extension. …”
Publicado 2016
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727por Liang, Yingchun, Xu, Xiaojie, Wang, Tao, Li, Ying, You, Wenye, Fu, Jing, Liu, Yang, Jin, Shuai, Ji, Quanbo, Zhao, Wei, Song, Qi, Li, Ling, Hong, Tian, Huang, Junjian, Lyu, Zhaohui, Ye, Qinong“…Here, we show that EGFR promotes breast tumor growth and metastasis by downregulating the tumor suppressor micoRNA-338-3p (miR-338-3p) and activating the EYA2 (EYA transcriptional coactivator and phosphatase 2) oncoprotein. …”
Publicado 2017
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728por Wu, Yantao, Li, Li, Zhu, Guoqiang, Li, Wenhui, Zhang, Nianzhang, Li, Shuangnan, Yao, Gang, Tian, Wenjun, Fu, Baoquan, Yin, Hong, Zhu, Xingquan, Yan, Hongbin, Jia, Wanzhong“…However, no E. canadensis G10 cases have been recorded in yaks until now. The aim of our study was to identify causative agents of echinococcosis in yaks in this region. …”
Publicado 2018
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729“…However, little is known about the functions and signaling properties of IGF2 variants in yaks. The over-expression vector and knockdown sequence of yak IGF2 were transfected into yak fibroblasts, and the effects were detected by a series of assays. …”
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730por Mo, Shi-Jing, Hou, Xun, Hao, Xiao-Yi, Cai, Jian-Peng, Liu, Xin, Chen, Wei, Chen, Dong, Yin, Xiao-Yu“…BACKGROUND: Our previous studies demonstrated that eyes absent homolog 4 (EYA4), a member of the eye development-related EYA family in Drosophila, is frequently methylated and silenced in hepatocellular carcinoma (HCC) specimens and associated with shorter survival. …”
Publicado 2018
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731por Goshu, Habtamu Abera, Wu, Xiaoyun, Chu, Min, Bao, Pengjia, Ding, Xuezhi, Yan, Ping“…Our results elucidated that a decreased CNV in the KLF6 gene is more highly associated (p < 0.05) with various growth traits than increased or normal CNVs in six-month-old and five-year-old Datong yak. Nevertheless, negative correlations between the DNA copy number and KLF6 gene expression were observed in the skeletal muscle of adult Datong yak. …”
Publicado 2018
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732por Basumatary, Sadhan K., Singh, Hukam, McDonald, H. Gregory, Tripathi, Swati, Pokharia, Anil K.“…The study reports the micro- and macrobotanical remains on wild Yak dung, providing evidence for understanding the diet, habitat, and ecology of extant and extinct megaherbivores. …”
Publicado 2019
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733por Varga, Lukas, Danis, Daniel, Skopkova, Martina, Masindova, Ivica, Slobodova, Zuzana, Demesova, Lucia, Profant, Milan, Gasperikova, Daniela“…Here we present a family with late-onset hearing loss as an autosomal dominant trait caused by a novel EYA4 mutation. CASE PRESENTATION: Forty-four years old female proband clinically investigated for progressive hearing loss and occasional dizziness with positive family history for deafness was subject to molecular-genetic testing. …”
Publicado 2019
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734por Xin, Jinwei, Chai, Zhixin, Zhang, Chengfu, Zhang, Qiang, Zhu, Yong, Cao, Hanwen, Zhong, Jincheng, Ji, Qiumei“…Yak (Bos grunniens) is an unique ruminant species in the Qinghai-Tibetan Plateau (QTP). …”
Publicado 2019
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735por Wu, Xiaoyun, Zhou, Xuelan, Ding, Xuezhi, Chu, Min, Liang, Chunnian, Pei, Jie, Xiong, Lin, Bao, Pengjia, Guo, Xian, Yan, Ping“…SIMPLE SUMMARY: The Ashidan yak is a new cultivated breed which has polled characteristics and a mild temperament. …”
Publicado 2019
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736por Ma, Xiaoming, Jia, Congjun, Chu, Min, Fu, Donghai, Lei, Qinhui, Ding, Xuezhi, Wu, Xiaoyun, Guo, Xian, Pei, Jie, Bao, Pengjia, Yan, Ping, Liang, Chunnian“…The development of muscles in the different stages of yak growth remains unclear. In this study, we selected the longissimus dorsi muscle tissue at three different growth stages of the yak, namely, 90-day-old fetuses (group E), six months old (group M), and three years old (group A). …”
Publicado 2019
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737“…The yak (Bosgrunniens) is a unique domestic bovine species that plays an indispensable role for herdsmen in the Qinghai–Tibet Plateau. …”
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738“…To this end, we respectively activated and inhibited AMPK in yak muscle using AICAR and STO-609 and analyzed the metabolism parameters. …”
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739por Hao, Lili, Yuan, Dongbo, Guo, Li, Hou, Wei, Mo, Xi, Yin, Jie, Yang, Aiguo, Li, Rui“…RESULTS: A total of 818 ticks (Dermacentor everestianus, 79.0%, 646/818; Haemaphysalis qinghaiensis, 21.0%, 172/818) were collected from yaks in 4 villages of Shiqu County. Only Bartonella melophagi was detected in tick samples, with a total prevalence of 30.1% (246/818). …”
Publicado 2020
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740por Xiong, Lin, Pei, Jie, Wu, Xiaoyun, Kalwar, Qudratullah, Liang, Chunnian, Guo, Xian, Chu, Min, Bao, Pengjia, Yao, Xixi, Yan, Ping“…The study indicated that under long-term ES during the cold season, the amount of fat in yaks was less, and fat mobilization was one of the main ways by which energy was obtained in yaks. …”
Publicado 2020
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