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12021por Luppi, Andrea I., Craig, Michael M., Pappas, Ioannis, Finoia, Paola, Williams, Guy B., Allanson, Judith, Pickard, John D., Owen, Adrian M., Naci, Lorina, Menon, David K., Stamatakis, Emmanuel A.“…Here, we combine graph theory and dynamic functional connectivity to compare resting-state functional MRI data from awake volunteers, propofol-anaesthetised volunteers, and patients with disorders of consciousness, in order to identify consciousness-specific patterns of brain function. …”
Publicado 2019
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12022“…In the cortex, they arise in the form of neuronal avalanches that capture ongoing and evoked neuronal activities at many spatial and temporal scales. …”
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12023por de Vries, Saskia E. J., Lecoq, Jerome A., Buice, Michael A., Groblewski, Peter A., Ocker, Gabriel K., Oliver, Michael, Feng, David, Cain, Nicholas, Ledochowitsch, Peter, Millman, Daniel, Roll, Kate, Garrett, Marina, Keenan, Tom, Kuan, Leonard, Mihalas, Stefan, Olsen, Shawn, Thompson, Carol, Wakeman, Wayne, Waters, Jack, Williams, Derric, Barber, Chris, Berbesque, Nathan, Blanchard, Brandon, Bowles, Nicholas, Caldejon, Shiella D., Casal, Linzy, Cho, Andrew, Cross, Sissy, Dang, Chinh, Dolbeare, Tim, Edwards, Melise, Galbraith, John, Gaudreault, Nathalie, Gilbert, Terri L., Griffin, Fiona, Hargrave, Perry, Howard, Robert, Huang, Lawrence, Jewell, Sean, Keller, Nika, Knoblich, Ulf, Larkin, Josh D., Larsen, Rachael, Lau, Chris, Lee, Eric, Lee, Felix, Leon, Arielle, Li, Lu, Long, Fuhui, Luviano, Jennifer, Mace, Kyla, Nguyen, Thuyanh, Perkins, Jed, Robertson, Miranda, Seid, Sam, Shea-Brown, Eric, Shi, Jianghong, Sjoquist, Nathan, Slaughterbeck, Cliff, Sullivan, David, Valenza, Ryan, White, Casey, Williford, Ali, Witten, Daniela M., Zhuang, Jun, Zeng, Hongkui, Farrell, Colin, Ng, Lydia, Bernard, Amy, Phillips, John W., Reid, R. Clay, Koch, Christof“…Here we report an open, large-scale physiological survey of activity in the awake mouse visual cortex: the Allen Brain Observatory Visual Coding dataset. …”
Publicado 2019
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12024por Obaid, Abdulmalik, Hanna, Mina-Elraheb, Wu, Yu-Wei, Kollo, Mihaly, Racz, Romeo, Angle, Matthew R., Müller, Jan, Brackbill, Nora, Wray, William, Franke, Felix, Chichilnisky, E. J., Hierlemann, Andreas, Ding, Jun B., Schaefer, Andreas T., Melosh, Nicholas A.“…This system has excellent recording performance, demonstrated via single unit and local-field potential recordings in isolated retina and in the motor cortex or striatum of awake moving mice. The modular design enables a variety of microwire types and sizes to be integrated with different types of pixel arrays, connecting the rapid progress of commercial multiplexing, digitisation and data acquisition hardware together with a three-dimensional neural interface.…”
Publicado 2020
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12025por Bhattacharjee, Anindya S., Konakamchi, Sasank, Turaev, Dmitrij, Vincis, Roberto, Nunes, Daniel, Dingankar, Atharva A., Spors, Hartwig, Carleton, Alan, Kuner, Thomas, Abraham, Nixon M.“…Intrinsic imaging of glomerular activity in anesthetized and awake mice reveals that Euclidean distance between activity patterns and the time needed for discriminations are anti-correlated. …”
Publicado 2019
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12026“…This context-conditioning effect was entirely absent when participants stayed awake the night after allergen exposure or were tested in a different context. …”
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12027por Maeda, Makishi, Chaki, Tomohiro, Kawaguchi, Ryoichi, Kimijima, Tomohiko, Yamakage, Michiaki“…CASE PRESENTATION: A 33-year-old man was scheduled to undergo laparoscopic colectomy. …”
Publicado 2020
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12028“…RESULTS: The percentage of awake time spent in sedentary activities was negatively correlated with attention (β = -14.20, t(12) = -2.47, p = 0.03) but not other cognitive domains (p > 0.05) after controlling for MVPA and medication dosage. …”
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12029“…Awakening by the α2-adrenergic antagonist completely eliminated this intermediate state and instantaneously restored awake dynamics and the top task performance while the anesthetic was still being infused. …”
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12030“…From the analysis of the interviews, three main themes emerged: (1) Day and night, neither awake nor asleep, (2) Anti Violence Centers: setting as a container of emotion? …”
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12031por Han, Kyung-Seok, Chen, Christopher H., Khan, Mehak M., Guo, Chong, Regehr, Wade G.“…Climbing fibers (CFs) from the inferior olive (IO) make strong excitatory synapses onto cerebellar Purkinje cell (PC) dendrites, and trigger distinctive responses known as complex spikes (CSs). We find that in awake mice, a CS in one PC suppresses conventional simple spikes (SSs) in neighboring PCs for several milliseconds. …”
Publicado 2020
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12032“…These dynamical features had distinct functional roles in speeding up inferences and made predictions that we confirmed in novel analyses of awake monkey recordings. Our results suggest that the basic motifs of cortical dynamics emerge as a consequence of the efficient implementation of the same computational function—fast sampling-based inference—and predict further properties of these motifs that can be tested in future experiments.…”
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12033por Alfonsa, Hannah, Burman, Richard J., Brodersen, Paul J. N., Newey, Sarah E., Mahfooz, Kashif, Yamagata, Tomoko, Panayi, Marios C., Bannerman, David M., Vyazovskiy, Vladyslav V., Akerman, Colin J.“…These changes underlie electrophysiological and behavioral markers of local sleep pressure within cortex — including the levels of slow-wave activity during non-rapid eye movement sleep — as well as low-frequency oscillatory activity and reduced performance levels in the sleep-deprived awake state. …”
Publicado 2023
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12034por Diekamp, Max, Jenter, Leonie, Schulte, Andreas G., Fricke, Oliver, Schmidt, Peter“…Case presentation: This case report describes a successful anterior tooth restoration, in awake state, in a 15-year-old boy with early childhood autism. …”
Publicado 2020
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12035“…Using calcium imaging in awake, freely licking mice, we show that Satb2 neurons respond to the five basic taste modalities. …”
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12036Synaptic communication mediates the assembly of a self-organizing circuit that controls reproductionpor Golan, M., Boulanger-Weill, J., Pinot, A., Fontanaud, P., Faucherre, A., Gajbhiye, D. S., Hollander-Cohen, L., Fiordelisio-Coll, T., Martin, A. O., Mollard, P.“…While their migration mode as individual GnRH neurons has been extensively studied, the role of GnRH-GnRH cell communication during migration remains largely unexplored. Here, we show in awake zebrafish larvae that migrating GnRH neurons pause at the nasal-forebrain junction and form clusters that act as interhemisphere neuronal ensembles. …”
Publicado 2021
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12037por Panaggio, Mark J., Abrams, Daniel M., Yang, Fan, Banerjee, Tanvi, Shah, Nirmish R.“…Setting appropriate dosages requires knowledge of a patient’s subjective pain, but collecting pain reports from patients can be difficult for clinicians and disruptive for patients, and is only possible when patients are awake and communicative. Here we investigate methods for estimating SCD patients’ pain levels indirectly using vital signs that are routinely collected and documented in medical records. …”
Publicado 2021
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12038“…Here, we use two-photon calcium imaging in awake mice to systematically map monocular and binocular responses to horizontal motion in four areas of the visual cortex. …”
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12039“…Using a novel storybook task, we found performance in children (N = 22, mean age = 51.23 months) was better following a nap compared to performance following an equivalent interval spent awake. Moreover, performance remained better the following day if a nap followed learning. …”
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12040“…Here we test this proposal through local iontophoretic application of the muscarinic receptor antagonist scopolamine and the nicotinic receptor antagonist mecamylamine, while recording single cells in parafoveal representations in awake fixating macaque V1. Collinear flankers generally reduced neuronal contrast sensitivity. …”
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