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12141por Bruns, Oliver T., Bischof, Thomas S., Harris, Daniel K., Franke, Daniel, Shi, Yanxiang, Riedemann, Lars, Bartelt, Alexander, Jaworski, Frank B., Carr, Jessica A., Rowlands, Christopher J., Wilson, Mark W.B., Chen, Ou, Wei, He, Hwang, Gyu Weon, Montana, Daniel M., Coropceanu, Igor, Achorn, Odin B., Kloepper, Jonas, Heeren, Joerg, So, Peter T.C., Fukumura, Dai, Jensen, Klavs F., Jain, Rakesh K., Bawendi, Moungi G.“…To demonstrate the unprecedented combination of deep penetration, high spatial resolution, multicolor imaging and fast-acquisition-speed afforded by the SWIR QDs, we quantified, in mice, the metabolic turnover rates of lipoproteins in several organs simultaneously and in real time as well as heartbeat and breathing rates in awake and unrestrained animals, and generated detailed three-dimensional quantitative flow maps of the mouse brain vasculature.…”
Publicado 2017
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12142“…Humans have a highly developed visual system, yet we spend a high proportion of our time awake ignoring the visual world and attending to our own thoughts. …”
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12143“…Functional MRI (fMRI) of fully awake and unrestrained dog ’volunteers' has been proven an effective tool to understand the neural circuitry and functioning of the canine brain. …”
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12144“…We record medial OFC (mOFC) single neuron activity in awake-behaving monkeys during a reward-guided lottery task. mOFC neurons signal the relative values of options via a divisive normalization function when animals freely choose between alternatives. …”
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12145por Arneodo, Ezequiel M., Penikis, Kristina B., Rabinowitz, Neil, Licata, Angela, Cichy, Annika, Zhang, Jingji, Bozza, Thomas, Rinberg, Dmitry“…MT cells respond heterogeneously to odorants, and how the responses encode stimulus features is unknown. We recorded in awake mice responses from “sister” MT cells that receive input from a functionally characterized, genetically identified glomerulus, corresponding to a specific receptor (M72). …”
Publicado 2018
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12146por Histed, Mark H.“…Here, to understand input-output transformations in cortical networks, we recorded spiking responses from visual cortex (V1) of awake mice of either sex while pairing sensory stimuli with optogenetic perturbation of excitatory and parvalbumin-positive inhibitory neurons. …”
Publicado 2018
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12147por Zhao, Ruohe, Zhou, Hang, Huang, Lianyan, Xie, Zhongcong, Wang, Jing, Gan, Wen-Biao, Yang, Guang“…Here, we used an in vivo two-photon imaging technique to monitor the activity of individual neurons in the ACC of awake, head restrained mice. Calcium imaging in the dorsal ACC revealed robust somatic activity in layer 5 (L5) pyramidal neurons in response to peripheral noxious stimuli, and the degree of evoked activity was correlated with the intensity of noxious stimulation. …”
Publicado 2018
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12148por Asokan, Meenakshi M., Williamson, Ross S., Hancock, Kenneth E., Polley, Daniel B.“…We track daily changes in sound processing using chronic widefield calcium imaging of L5 axon terminals on the dorsal cap of the IC in awake, adult mice. Sound level growth functions at the level of the auditory nerve and corticocollicular axon terminals are both strongly depressed hours after noise-induced damage of cochlear afferent synapses. …”
Publicado 2018
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12149por Bagur, Sophie, Averseng, Martin, Elgueda, Diego, David, Stephen, Fritz, Jonathan, Yin, Pingbo, Shamma, Shihab, Boubenec, Yves, Ostojic, Srdjan“…A1 activity was recorded in awake ferrets while they either passively listened or actively discriminated stimuli in a range of Go/No-Go paradigms, with different sounds and reinforcements. …”
Publicado 2018
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12150por Kienitz, Ricardo, Schmiedt, Joscha T., Shapcott, Katharine A., Kouroupaki, Kleopatra, Saunders, Richard C., Schmid, Michael Christoph“…Here we show using array recordings in visual cortical area V4 of two awake macaques that presenting separate visual stimuli to the excitatory center and suppressive surround of neuronal receptive fields (RFs) elicits rhythmic multi-unit activity (MUA) at 3–6 Hz. …”
Publicado 2018
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12151“…Though rapid sequence intubation is the recommended method for securing airway in these patients, other methods like delayed sequence intubation awake intubation and double setup approach can be used in specific subgroups. …”
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12152“…Change in memory accuracy also did not differ when probed after a nap compared to the change in memory accuracy after an interval awake. However, when memory was probed again following overnight sleep, the change in memory accuracy was greater if the child napped the previous day. …”
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12153“…We report the clinical course of an intoxicated patient found down with blunt head trauma and concurrent alcoholic cirrhosis who was awake and responsive in the field. Hospital course was characterized by a rapidly deteriorating neurological examination with progressive subdural and subarachnoid hemorrhage and precipitating neurosurgical decompression and critical care management. …”
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12154por Hiromitsu, Kentaro, Asai, Tomohisa, Saito, Shoko, Shigemune, Yayoi, Hamamoto, Kanako, Shinoura, Nobusada, Yamada, Ryoji, Midorikawa, Akira“…To examine this, we measured the ESS of patients with brain tumors before and after awake craniotomy. A self-reported questionnaire called the Embodied Sense of Self Scale (ESSS) was used to measure the ESS in patients with brain tumors before and after surgery. …”
Publicado 2018
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12155por Schapiro, Anna C., McDevitt, Elizabeth A., Rogers, Timothy T., Mednick, Sara C., Norman, Kenneth A.“…We used functional magnetic resonance imaging (fMRI) pattern analysis to track item-level replay in the hippocampus during an awake rest period after participants studied 15 objects and completed a memory test. …”
Publicado 2018
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12156por Prichard, Ashley, Chhibber, Raveena, Athanassiades, Kate, Spivak, Mark, Berns, Gregory S.“…Are some modalities learned better than others? We used awake fMRI in 19 dogs over a series of three experiments to measure reward-related learning of visual, olfactory, and verbal stimuli. …”
Publicado 2018
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12157por Watson, Brendon O.“…Multiple lines of converging evidence now point to the infraslow oscillation (ISO) as a mediator of brain sub-states, with impacts ranging from the creation of resting state networks (RSNs) in awake subjects to interruptions in neural activity during sleep. …”
Publicado 2018
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12158por Francavilla, Ruggiero, Villette, Vincent, Luo, Xiao, Chamberland, Simon, Muñoz-Pino, Einer, Camiré, Olivier, Wagner, Kristina, Kis, Viktor, Somogyi, Peter, Topolnik, Lisa“…They are interconnected through gap junctions but demonstrate sparse spike coupling in vitro. In awake mice, VIP-LRPs decrease their activity during theta-run epochs and are more active during quiet wakefulness but not coupled to sharp-wave ripples. …”
Publicado 2018
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12159por Romano, Vincenzo, De Propris, Licia, Bosman, Laurens WJ, Warnaar, Pascal, ten Brinke, Michiel M, Lindeman, Sander, Ju, Chiheng, Velauthapillai, Arthiha, Spanke, Jochen K, Middendorp Guerra, Emily, Hoogland, Tycho M, Negrello, Mario, D'Angelo, Egidio, De Zeeuw, Chris I“…We developed a sensory-driven adaptation protocol for reflexive whisker protraction and recorded Purkinje cell activity from crus 1 and 2 of awake mice. Before training, simple spikes of individual Purkinje cells correlated during reflexive protraction with the whisker position without lead or lag. …”
Publicado 2018
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12160por Hudry, Eloise, Klickstein, Jacob, Cannavo, Claudia, Jackson, Rosemary, Muzikansky, Alona, Gandhi, Sheetal, Urick, David, Sargent, Taylie, Wrobleski, Lauren, Roe, Allyson D, Hou, Steven S, Kuchibhotla, Kishore V, Betensky, Rebecca A, Spires-Jones, Tara, Hyman, Bradley T“…Using two-photon calcium imaging in awake mice to record visually evoked responses, we found that genetic removal of APOE improved neuronal responses in adult APP/PSEN1 mice (8–10 mo). …”
Publicado 2019
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