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  1. 12441
    “…Here, we report a new role for NAADP in arrhythmogenic Ca(2+) release in cardiac myocytes evoked by β-adrenergic stimulation. Infusion of NAADP into intact cardiac myocytes induced global Ca(2+) signals sensitive to inhibitors of both acidic Ca(2+) stores and ryanodine receptors and to NAADP antagonist BZ194. …”
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    Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-mediated Calcium Signaling and Arrhythmias in the Heart Evoked by β-Adrenergic Stimulation
  2. 12442
    “…Voltage-sensitive fluorescent proteins (VSFPs) are a family of genetically-encoded voltage indicators (GEVIs) reporting membrane voltage fluctuation from genetically-targeted cells in cell cultures to whole brains in awake mice as demonstrated earlier using 1-photon (1P) fluorescence excitation imaging. …”
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    Two-photon voltage imaging using a genetically encoded voltage indicator
  3. 12443
    “…The loop suture could be removed later while the patient was awake, or it could be tied to advance the muscle. …”
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    Loop Suture Technique for Optional Adjustment in Strabismus Surgery
  4. 12444
    por Potjans, Tobias C., Diesmann, Markus
    Publicado 2014
    “…The simulated spontaneous activity is asynchronous irregular and cell-type specific firing rates are in agreement with in vivo recordings in awake animals, including the low rate of layer 2/3 excitatory cells. …”
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    The Cell-Type Specific Cortical Microcircuit: Relating Structure and Activity in a Full-Scale Spiking Network Model
  5. 12445
    “…The paper is focused on real-time drowsiness detection technology rather than on long-term sleep/awake regulation prediction technology. We have developed our own vision system in order to obtain robust and optimized driver indicators able to be used in simulators and future real environments. …”
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    Fusion of Optimized Indicators from Advanced Driver Assistance Systems (ADAS) for Driver Drowsiness Detection
  6. 12446
    por Ojemann, George A.
    Publicado 2013
    “…Findings from recordings of human temporal cortical single neuron activity during several measures of language, including object naming and word reading are reviewed and related to changes in activity in the same neurons during recent verbal memory and verbal associative learning measures, in studies conducted during awake neurosurgery for the treatment of epilepsy. …”
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    Human Temporal Cortical Single Neuron Activity during Language: A Review
  7. 12447
    “…Non-invasive assessment of hemispheric dominance for receptive language using magnetoencephalography (MEG) is now a well-established procedure used across several epilepsy centers in the context of pre-surgical evaluation of children and adults while awake, alert and attentive. However, the utility of MEG for the same purpose, in cases of sedated patients, is contested. …”
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    Assessment of hemispheric dominance for receptive language in pediatric patients under sedation using magnetoencephalography
  8. 12448
    “…Electroencephalogram (EEG) was recorded from 57 women (aged 24.07±3.67 years) having a natural menstrual cycle as well as from 57 women (aged 22.37±2.20 years) using oral contraceptives while they sat in an armchair with eyes closed. …”
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    Resting state alpha frequency is associated with menstrual cycle phase, estradiol and use of oral contraceptives
  9. 12449
    “…These results introduce fUS as a powerful novel neuroimaging method, which could be extended to portable systems for three-dimensional functional connectivity imaging in awake and freely moving rodents.…”
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    Functional ultrasound imaging of intrinsic connectivity in the living rat brain with high spatiotemporal resolution
  10. 12450
    por Coveney, Catherine M
    Publicado 2014
    “…It draws on data, collected in the UK from 25 semi-structured interviews, to discuss the complex ways in which working patterns and social activities impact upon experiences and expectations of sleep in our wired awake world. The data show that, typically, sleep is valued and considered to be important for health, general wellbeing, appearance and physical and cognitive functioning. …”
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    Managing sleep and wakefulness in a 24-hour world
  11. 12451
    “…We introduced BB while the patient was still awake: Left-side one-lung ventilation (OLV) was established and anesthesia was induced. …”
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    Management of traumatic pneumothorax with massive air leakage: role of a bronchial blocker: a case report
  12. 12452
    “…In recent years optogenetics has rapidly become an essential technique in neuroscience. …”
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    A wirelessly controlled implantable LED system for deep brain optogenetic stimulation
  13. 12453
    “…RESULTS: BIS value was significantly lower with sevoflurane at all MAC values as compared to isoflurane, except in the beginning and at MAC awake. However, both the drugs proved to be cardiostable. …”
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    Comparison of equi-minimum alveolar concentration of sevoflurane and isoflurane on bispectral index values during both wash in and wash out phases: A prospective randomised study
  14. 12454
    “…Here using in vivo two-photon imaging in awake mice, we found that learning-induced spine reorganization of L2/3 excitatory neurons occurs in the distal branches of their apical dendrites in L1 but not in the perisomatic dendrites. …”
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    Subtype-specific plasticity of inhibitory circuits in motor cortex during motor learning
  15. 12455
    por Cicmil, Nela, Krug, Kristine
    Publicado 2015
    “…We reconsider the function and organization of visual cortex according to results obtained from stimulation techniques, with a special emphasis on electrical stimulation of small groups of cells in awake subjects who can report their visual experience. …”
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    Playing the electric light orchestra—how electrical stimulation of visual cortex elucidates the neural basis of perception
  16. 12456
    “…Emerging neural theories of consciousness suggest a correlation between a specific type of neural dynamical complexity and the level of consciousness: When awake and aware, causal interactions between brain regions are both integrated (all regions are to a certain extent connected) and differentiated (there is inhomogeneity and variety in the interactions). …”
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    Complexity of Multi-Dimensional Spontaneous EEG Decreases during Propofol Induced General Anaesthesia
  17. 12457
    “…The vertex potential is the largest response that can be recorded in the electroencephalogram of an awake, healthy human. It is elicited by sudden and intense stimuli, and is composed by a negative–positive deflection. …”
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    Laser-Evoked Vertex Potentials Predict Defensive Motor Actions
  18. 12458
    “…Importantly, this technique can be successfully completed in awake rodents if conducted in conjunction with other JoVE articles that covered requisite surgical procedures. …”
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    Rodent Brain Microinjection to Study Molecular Substrates of Motivated Behavior
  19. 12459
    “…METHODS: We assessed EEG spectral power, coherence, phase lag, Pearson and partial correlations, and epileptiform activity during the awake, slow wave sleep, and REM sleep states in 137 children aged 2 to 6 years with autism (n = 87), developmental delay without autism (n = 21), or typical development (n = 29). …”
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    State-Dependent Differences in Functional Connectivity in Young Children With Autism Spectrum Disorder
  20. 12460
    “…The latter includes the development of a novel mouse cradle designed to maintain whole-body normothermia in anesthetized mice during fMRI in a way that reflects the thermal status of awake, resting mice. Applying mild noxious heat stimuli to wildtype mice resulted in highly significant BOLD patterns in anatomical brain structures forming the pain matrix, which comprise temporal signal intensity changes of up to 6% magnitude. …”
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    Normothermic Mouse Functional MRI of Acute Focal Thermostimulation for Probing Nociception
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