“…We also applied ASTRA to the first report of two-photon mesoscopic imaging of hundreds of astrocytes in awake mice, documenting large-scale redundant and synergistic interactions in extended astrocytic networks. …”
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“…Differences in the physical work strain were compared between younger (≤ 44-year-old) and older (≥ 45-year-old) employees and between morning and evening shifts. …”
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“…Nocturnal and circadian intraocular pressure (IOP) fluctuations are important issues in glaucoma treatment. Ripasudil 0.4% eye drops, a new glaucoma medication, lowers IOP by increasing aqueous humor outflow through the trabecular meshwork. …”
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“…In this study, we use mesoscale two-photon calcium imaging to examine spontaneous activity of cholinergic and noradrenergic axons in awake mice in order to determine the interaction between arousal/movement state transitions and neuromodulatory activity across the dorsal cortex at distances separated by up to 4 mm. …”
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“…To study age-related differences in the human glymphatic system, we measured the influx and efflux activities of the glymphatic system via two non-invasive diffusion magnetic resonance imaging (MRI) methods, ultra-long echo time and low-b diffusion tensor imaging (DTI(low–b)) measuring the subarachnoid space (SAS) flow along the middle cerebral artery and DTI analysis along the perivascular space (DTI-ALPS) along medullary veins in 22 healthy volunteers (aged 21–75 years). We first evaluated the circadian rhythm dependence of the glymphatic activity by repeating the MRI measurements at five time points from 8:00 to 23:00 and found no time-of-day dependence in the awake state under the current sensitivity of MRI measurements. …”
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“…Interestingly, rapid repetitive whisker touch evoked excitatory responses in somatostatin-expressing inhibitory neurons, but not when the intercontact interval was long. …”
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“…Experiment 1 confirmed the benefit of sleep for recall and recognition of word meanings, with better retention after 12 hours including overnight sleep than 12 hours awake. Experiment 2, which was preregistered, further explored this sleep benefit. …”
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“…METHODS: We measured tail withdrawal latencies to a nociceptive thermal stimulus (infrared beam) in Sprague-Dawley rats–first when awake (unanesthetized), and then subsequently during i.v. chloral hydrate anesthesia. …”
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“…We developed protocols to allow for consistent spatial recordings of LFPs across multiple flies, allowing us to compare the LFP activity across awake and sleep periods and further compare the same to induced sleep. …”
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“…CONCLUSIONS: Procedural pain is an important consideration for many patients, especially in awake procedures. Appropriate counseling is crucial to support informed consent and enhance patient outcomes. …”
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“…All patients were treated with a minimally invasive technique using local anesthesia WALANT (wide-awake local anesthesia no tourniquet) in the ambulatory setting. …”
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“…Fourteen intubated patients for acute respiratory failure received six trials of 25 minutes randomly applying PSV and NAVA at three different propofol infusions: awake, light, and deep sedation. We assessed the occurrence of RTBs at each protocol step. …”
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“…However its role as adjuvant to DCS and alternative only when awake surgery is not available must be emphasized.…”
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“…SIGNIFICANCE: Fiber photometry is a widely used technique in modern behavioral neuroscience, employing genetically encoded fluorescent sensors to monitor neural activity and neurotransmitter release in awake-behaving animals, However, analyzing photometry data can be both laborious and time-consuming. …”
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“…The present study aimed to investigate the knowledge, attitude, and practice of students of Arak University of Medical Sciences (Iran) in 2020 concerning CAM. …”
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“…Furthermore, two control experiments (G8(awake) and G8(sleep)) supported the idea that a night of sleep contributes to the skill consolidation of the evening group. …”
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“…The intervention increased sleep efficiency by lowering awake time after falling asleep.…”
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“…Dogs live in a complex social environment where they regularly interact with conspecific and heterospecific partners. Awake dogs are able to process a variety of information based on vocalisations emitted by dogs and humans. …”
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“…The subjects were 21 healthy children aged 3 to 4 years. They were asked to attach a small instrument for calculating sleeping hours objectively, over 3 consecutive nights. …”
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“…INTRODUCTION AND IMPORTANCE: Wide Awake Local Anesthesia No Tourniquet (WALANT) is a surgical technique used in hand surgery that allows for active patient participation during surgery while avoiding the pain and discomfort associated with general anesthesia and tourniquets. …”
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