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  1. 13281
    por Zheng, Jian-Qiao, Du, Li, Zhang, Wei-Yi
    Publicado 2022
    “…BACKGROUND: Epiglottic cysts is a rare but potentially lethal supraglottic airway pathology in infants due to the high risk of cannot intubation or cannot ventilation. Awake fiberoptic intubation appeared to be the safest technique, but it is very challenging in infants with large epiglottic cysts. …”
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    Aspiration as the first-choice procedure for airway management in an infant with large epiglottic cysts: A case report
  2. 13282
    “…METHODS: This descriptive-analytical study was conducted on 320 cancer patients in Arak. For gathering information, a researcher-made questionnaire was used. …”
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    Complementary and alternative medicine application in cancer patients in Iran
  3. 13283
    “…Participants will wear a blinded CGM device and an actigraphy monitor to differentiate awake and sleep times for 10 weeks. Participants will be asked to complete three short surveys each day using a bespoke mobile phone app, a technique known as ecological momentary assessment. …”
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    Hypo‐METRICS: Hypoglycaemia—MEasurement, ThResholds and ImpaCtS—A multi‐country clinical study to define the optimal threshold and duration of sensor‐detected hypoglycaemia that impact the experience of hypoglycaemia, quality of life and health economic outcomes: The study protocol
  4. 13284
    “…CONCLUSIONS: Reduced loudness tolerance is demonstrated during daytime hearing deprivation in contrast to nighttime; this may be due to increased central gain in the awake cortex.…”
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    Transient decrease in sound tolerance levels following hearing deprivation in normal-hearing subjects
  5. 13285
    “…We included 73 middle-aged participants (mean (SD) age: 67.0 (6.16) years), comprising 37 offspring of long-lived families, 36 of their partners, and 35 young participants (22.8 (3.96) years). …”
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    The association between continuous ambulatory heart rate, heart rate variability, and 24-h rhythms of heart rate with familial longevity and aging
  6. 13286
    “…Therefore, in this study, we monitored the activity changes in the PF nucleus in PD rats during a quiet awake state after GP-DBS. We found that GP-DBS could reverse the electrical activity of the PF nucleus in PD model rats, including the discharge pattern of the neurons and the local field potential (0.7–12 and 12–70 Hz). …”
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    Deep brain stimulation in the globus pallidus alleviates motor activity defects and abnormal electrical activities of the parafascicular nucleus in parkinsonian rats
  7. 13287
    “…COVID-19 patients who may require invasive therapeutic procedures such as extracorporeal membrane oxygenation (ECMO) have high symptom burden and in-hospital mortality. In addition, awake patients on ECMO are new in the intensive care unit (ICU) setting. …”
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    Specialist Palliative Care Consultations in COVID-19 Patients in the ICU—A Retrospective Analysis of Patient Characteristics and Symptoms at a German University Hospital
  8. 13288
    “…METHODS: The data of patients over the age of 65 years who reported to the ER and had appendectomy after being diagnosed with AA were evaluated in this retrospective cohort study. …”
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    A comparative study of the RIPASA and Alvarado scores in geriatric patients diagnosed with acute appendicitis
  9. 13289
    “…CASE PRESENTATION: We report a case of a 24-year-old woman who presented with partial tracheal rupture and pneumothorax caused by a knife stab injury to the neck. …”
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    What we have learned from a patient with partial tracheal rupture caused by penetrating neck injuries: a case report
  10. 13290
    “…To investigate, we recorded spike trains from awake mice and estimated the network time constants using a statistical method to combine evidence from multiple weak signal-to-noise ratio neurons. …”
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    Differences in temporal processing speeds between the right and left auditory cortex reflect the strength of recurrent synaptic connectivity
  11. 13291
    “…To determine whether eight days of dark exposure has a lasting negative impact on responses to classic grating stimuli, neural activity was recorded before and after dark exposure in awake head-fixed mice using two-photon calcium imaging. …”
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    Visual experience has opposing influences on the quality of stimulus representation in adult primary visual cortex
  12. 13292
    “…To investigate this, we administered microinjections of picrotoxin, a gamma aminobutyric acid (GABA) antagonist, to the rabbit cortex in the awake state to mimic the functional deficiency of GABAergic interneurons. …”
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    Brain tissue oxygen dynamics while mimicking the functional deficiency of interneurons
  13. 13293
    “…We revisited our previously developed method for extraction of the cerebral metabolic rate of O(2) (CMRO(2)) based on 2-photon pO(2) measurements around diving arterioles and applied this method to estimate baseline CMRO(2) in awake mice across cortical layers. To our surprise, our results revealed a decrease in baseline CMRO(2) from layer I to layer IV. …”
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    Baseline oxygen consumption decreases with cortical depth
  14. 13294
    “…Next, in vivo two-photon calcium imaging was performed in awake mice after four different treatments, including 5-HT, capsaicin, and each vehicle. …”
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    Multiplexed Representation of Itch and Pain and Their Interaction in the Primary Somatosensory Cortex
  15. 13295
    por Khosravani, Mahboobeh, Nejat, Nazi
    Publicado 2022
    “…METHODS: A qualitative approach involving face to face semi-structured interviews conducted in Arak city, Iran. In total, 24 participants were recruited through purposive sampling. …”
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    Spiritual Experiences of Patients in the Cancer Trajectory: A Content Analysis
  16. 13296
    “…RESULTS: To overcome this challenge, we proposed a biocompatible nanoplatform that enables high-definition ultrasound imaging-guided, intensity-adjustable, and long-lasting analgesia in a postoperative pain management model in awake mice. The nanoplatform was constructed by incorporating perfluoropentane and levobupivacaine with red blood cell membranes decorated liposomes. …”
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    Intensity-adjustable pain management with prolonged duration based on phase-transitional nanoparticles-assisted ultrasound imaging-guided nerve blockade
  17. 13297
    “…Under favorable conditions, disseminated dormant tumor cells ‘re-awake’, resume their proliferation and thus colonize distant sites. …”
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    Regulation of Metastatic Tumor Dormancy and Emerging Opportunities for Therapeutic Intervention
  18. 13298
    “…RESULTS: We demonstrate simultaneous two-photon imaging of GCaMP and extracellular electrophysiology of neural activity in awake head-fixed and freely moving mice. Using the collected information, we perform correlation analysis to reveal positive correlation between optical and local field potential recordings. …”
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    GRINtrode: a neural implant for simultaneous two-photon imaging and extracellular electrophysiology in freely moving animals
  19. 13299
    “…METHODS: This open-label randomized clinical trial included 116 children aged 5–15 years with FAPP who met the ROME-4 criteria and were referred to the gastrointestinal clinic of Amir-Kabir Hospital in Arak in 2020–2021. …”
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    Ability of polymicrobial probiotic and mono-strain probiotic to reduce functional abdominal pain in children: a randomized clinical trial
  20. 13300
    “…Nine healthy male participants [26 ± 1.3 years, body mass index (BMI) 24.8 ± 0.8 kg/m(2)] (mean ± SD) were recruited. …”
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    Acute impact of light at night and exogenous melatonin on subjective appetite and plasma leptin
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