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  1. 14061
    “…Additional outcomes include VAS score change at 1-, 3-, and 6-month follow-ups; responder rate (VAS score improving by 50%); achievement rate of a desirable pain state (VAS score ≤ 4); awake times during sleep; Beck Depression Inventory for depression evaluation; short-form 36 for quality of life evaluation; drug usage; and satisfaction rating of the device. …”
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    Spinal cord stimulation for chronic intractable trunk or limb pain: study protocol for a Chinese multicenter randomized withdrawal trial (CITRIP study)
  2. 14062
    “…CASE PRESENTATION: A 28-year-old man and a 30-year-old man caught their hands in a high-speed drill and lathe, respectively, which caused a sudden forced flexion of their wrists. …”
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    Traumatic index extensor tendon attenuation mimicking closed tendon rupture: two case reports
  3. 14063
    “…The accuracy of sleep/wakefulness detection was 82.3±8.66% with a sensitivity of 87.8±10.8 % (sleep), specificity of 71.4±18.5% (awake), F1 of 88.1±9.3% and Cohen’s kappa of 0.54. …”
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    Sleep/Wakefulness Detection Using Tracheal Sounds and Movements
  4. 14064
    “…In COUGH-1, 730 participants have been randomised and treated; 74% are female with mean age of 59 years (39% over 65 years), and mean baseline duration of cough of 11.5 years. …”
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    Design and rationale of two phase 3 randomised controlled trials (COUGH-1 and COUGH-2) of gefapixant, a P2X3 receptor antagonist, in refractory or unexplained chronic cough
  5. 14065
    “…The median (interquartile range, IQR) age of the participants was 73 (69–78) years, with 317 (37.1%) men and 538 (62.9%) women. …”
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    Association between objectively measured walking steps and sleep in community-dwelling older adults: A prospective cohort study
  6. 14066
    “…Results: Statistically, symptoms of depression and fatigue, subjective sleep, and physical activity levels did neither increase, nor decrease over time, although descriptively, both moderate and vigorous physical activity levels decreased, and fatigue and subjective insomnia increased. Time awake after sleep onset statistically significantly decreased, while light sleep duration increased by trend. …”
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    Among Persons With Multiple Sclerosis (MS), Objective Sleep, Psychological Functioning, and Higher Physical Activity Scores Remained Stable Over 2 Years—Results From a Small Study Under Naturalistic Conditions
  7. 14067
    “…Prone position was used frequently in both intubated (67.5%) and awake (27.8%) patients. Medications consisted of antivirals agents (92.7%), corticosteroids (93.8%), tocilizumab (57.7%), and intermediate or high doses of anticoagulants (83.5%). …”
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    Critically ill COVID-19 patients attended by anesthesiologists in northwestern Spain: A multicenter prospective observational study()
  8. 14068
    “…CASE PRESENTATION: A 77-year-old awake and collaborating male patient with mild SARS-CoV-2 pneumonia and ventilated with Helmet CPAP, showed sudden worsening of gas exchange without dyspnea. …”
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    SARS-CoV-2 pneumonia succesfully treated with cpap and cycles of tripod position: a case report
  9. 14069
    “…Here, we investigate if a single psychedelic dose of psilocybin changes synaptic vesicle protein 2A (SV2A) and 5-HT(2A)R density in the pig brain. Twenty-four awake pigs received either 0.08 mg/kg psilocybin or saline intravenously. …”
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    A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT(2A) Receptor Density in the Pig Brain
  10. 14070
    “…This study was approved by Ethical Committee of Arak University of Medical Sciences (No. IR.Arakmu.Rec.1395.450) in March, 2017, and the trial was registered and approved by the Iranian Registry of Clinical Trials (IRCT No. …”
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    Comparing intravenous dexmedetomidine and clonidine in hemodynamic changes and block following spinal anesthesia with ropivacaine in lower limb orthopedic surgery: a randomized clinical trial
  11. 14071
    “…METHODS: Term newborns underwent awake, handheld swept-source optical coherence tomography (SS-OCT) in this prospective cohort study. …”
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    Choroidal Thickness by Handheld Swept-Source Optical Coherence Tomography in Term Newborns
  12. 14072
    “…Presymptomatic mutant mice (awake-freely moving) were acclimated to systemic mild hypothermia using an environmentally controlled chamber (12 h-on/12-off or 24 h-on/24 h-off) to lower body temperature (1–3 °C). …”
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    Chronic Intermittent Mild Whole-Body Hypothermia Is Therapeutic in a Mouse Model of ALS
  13. 14073
    “…Here, we describe behavior and neural activity during sleep and awake states in adult C. elegans hermaphrodites using new microfluidic methods. …”
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    Sleep Analysis in Adult C. elegans Reveals State-Dependent Alteration of Neural and Behavioral Responses
  14. 14074
    “…Recent studies showed similarity in eye movement patterns between wakefulness and rapid eye movement (REM) sleep, indicating that the brain status of REM sleep likely resembles that of awake status. …”
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    Tracking Eye Movements During Sleep in Mice
  15. 14075
    “…RESULTS: Days WFH were associated with more time spent sleeping relative to awake, and the effect size was large (F = 7.4; p = 0.01; η(p)(2) = 0.22). …”
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    Working from home during the COVID-19 outbreak in Sweden: effects on 24-h time-use in office workers
  16. 14076
    por Stöckel, Tino, Grimm, Robert
    Publicado 2021
    “…School physical education (PE) has the potential to contribute to public-health promotion and well-being, but oftentimes students' lack of motivation toward PE or physical activity in general, especially during adolescence, diminishes, or eradicates the positive effects associated with PE. …”
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    Psychophysiological Benefits of Real-Time Heart Rate Feedback in Physical Education
  17. 14077
    “…As a result, inhibition of HDAC6 awaked the dormant primordial follicles of mice in vitro. …”
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    HDAC6 regulates primordial follicle activation through mTOR signaling pathway
  18. 14078
    “…INTERVENTIONS: COVID-19 patients being positioned in the prone position either whilst awake or mechanically ventilated. MEASUREMENTS: Primary outcomes were oxygenation parameters (PaO₂/FiO₂ ratio, PaCO₂, SpO₂). …”
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    Effect of prone versus supine position in COVID-19 patients: A systematic review and meta-analysis
  19. 14079
    “…There has been interest in the use of nonintubated techniques for video-assisted thoracoscopic surgery (VATS) in both awake and sedated patients. The authors’ centre developed a nonintubated technique with spontaneous ventilation for use in a patient under general anaesthesia using a phrenic nerve block. …”
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    Phrenic nerve block during nonintubated video-assisted thoracoscopic surgery: a single-centre, double-blind, randomized controlled trial
  20. 14080
    “…For the MSE analysis, area 1_5 in awake state was lower, and areas 6_15 and 6_20 in sleep state were higher in PIE with a significant statistical difference. …”
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    Impairment of Cardiac Autonomic Nerve Function in Pre-school Children With Intractable Epilepsy
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