“…In the early evening (end of exercise 3.5 h before bedtime), participants performed either: (i) a 1 h high-intensity interval running session (HIGH, 6 × 5 min at 90% VO(2peak) interspersed with 5 min recovery); (ii) a 1 h low-intensity running session (LOW, 60 min at 45% VO(2peak)) or (iii) no exercise (CON). …”
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“…BACKGROUND: Nocturnal hypertension, defined by a mean asleep systolic blood pressure (SBP)/diastolic blood pressure (BP) ≥120/70 mm Hg, and nondipping SBP, defined by an awake‐to‐asleep decline in SBP <10%, are each associated with increased risk for cardiovascular disease. …”
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“…To evaluate the therapeutic efficacy of NMDAR antagonism in this model, we treated the mice with MK801, Tat-NR2B9c, and L-JNKI-1 at doses that were neuroprotective in the MCAO model, and 30 min later, they were subjected to 120 min of dMCAO either in the awake state or under anesthesia with normothermic controls. …”
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“…Furthermore, crystallographic analysis of the complex with a modified VP1-2A peptide (APAKE|LLNFD) containing a Gln-to-Glu substitution reveals an identical mode of peptide binding and explains the ability of foot-and-mouth disease virus 3C(pro) to cleave sequences containing either P1-Gln or P1-Glu. …”
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“…In the first three conditions, six (54%), eight (53%), and five participants (36%) reported lucid dreams during the morning sleep period, whereas three, (27%), four (27%), and two participants (14%) produced PSG-verified eye signals. In contrast, in the reading condition, only one (9%) participant reported lucid dreams and no eye movements. …”
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“…To determine if this also induces long-term plastic changes on cortical maps and connectivity in the visual cortex and higher associative areas, mesoscopic calcium imaging was performed in head-fixed awake GCaMP6s adult mice before and after conditioning. …”
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“…Whereas this was shown in the conscious process of awake patients by different measures and at different time scales, dreams came very seldom into the focus of investigation. …”
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“…The observational scores ICDSC and Nu-DESC showed a significantly better performance in awake and drowsy patients (RASS 0/−1) when compared with other sedation levels. …”
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“…This study was performed to evaluate feasibility and reproducibility of two-dimensional shear wave elastography (2D SWE) for evaluation of tissue stiffness and to examine technical factors that affect shear wave speed (SWS) measurements in adult dogs. Nine healthy, 2 year-old, adult beagles with the median weight of 9.8 kg were included. …”
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“…Conventionally, higher average time awake, lower average time asleep, and lower sleep efficiency define poor sleep. …”
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“…No differences were detected in Steward score out of PACU (p = 0.213) and from the time of the end of operation to fully awake (p = 0.417). CONCLUSION: Intravesical dexmedetomidine instillation reduces postoperative urinary discomfort and urethra pain and improves satisfaction in male patients under general anesthesia. …”
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“…Independent risk factors significantly associated with development of DP were bottle-only feeding (adjusted odds ratio (aOR) = 4.65; 95% CI: 2.70–8.00), little tummy time when awake (aOR = 3.51, 95% CI: 1.71–7.21), delay of motor development (aOR = 2.85, 95% CI: 1.08–7.49), and obesity at diagnosis (aOR = 2.45, 95% CI: 1.02–5.90). …”
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“…Five items were selected from CARIES-QC for inclusion in the provisional classification system; ‘hurt’, ‘annoy’, ‘carefully’, ‘kept awake’ and ‘cried’. Validation interviews were conducted with 20 children aged 5–16 years old. …”
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“…Two independent founding events were found for Pisang Awak genotypes. Two HE patterns, corresponding to genotypes Pelipita and Klue Teparod, show an over-representation of B genome contribution. …”
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“…In summary, subjects with COPD with TIB ≥9 h·night(−1) have more fragmented sleep, are more sedentary and less physically active than those with <9 h·night(−1), independently of the awake time. Sleep quality is frequently poor and even worse in patients classified as physically inactive.…”
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“…Withdrawal of excitatory inputs to the hypoglossal motor nucleus (HMN) from wake to sleep contributes to this reduced activity. Several awake–active neurotransmitters with inputs to the HMN (e.g. serotonin [5-HT]) inhibit K(+) leak mediated by TASK-1/3 channels on hypoglossal motoneurons, leading to increased neuronal activity in vitro. …”
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“…Participants were 38 children with ASD (8–12 years) meeting the study definition of minimally verbal/nonverbal language. …”
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“…RESULTS: A significant difference in optic nerve sheath diameter was found between two groups at T(15), T(30), T(45) (4.64 ± 0.48 mm and 4.50 ± 0.29 mm, respectively, p = 0.031;4.77 ± 0.45 mm and 4.62 ± 0.28 mm, respectively, p = 0.036;4.84 ± 0.46 mm and 4.65 ± 0.30 mm, respectively, p = 0.012), while there was no significant difference at T(awake) and other time points. CONCLUSION: During laparoscopic gynecological surgery lasting more than 2 h, the optic nerve sheath diameter was slightly larger in the propofol group than that in the sevoflurane group in the first 45 min. …”
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“…We suggest a trial of awake prone positioning in patients who remain hypoxemic; however, this requires close monitoring, and clear failure and escalation criteria. …”
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“…We found 5-Hz oscillations in membrane potential (V(m)) and firing rates evoked in single neurons in response to the familiar stimulus, consistent with previous studies. …”
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