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  1. 14441
    “…Food choice may play a role, however simply eating at night when the body is primed for sleep may have implications for health. …”
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  2. 14442
    “…By changing only the time at which the rodents are forced to be awake, the model reproduces some key experimental results from the previous study, including correct proportions of time spent in each stage of sleep as a function of circadian time and the differences in total wake time and SWS bout durations in the rodents representing night-shift workers and those representing day-shift workers. …”
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  3. 14443
    “…When merging all sleep stages into a single class and thereby evaluating an awake–sleep classifier, we achieved a sensitivity of 94.8% and a specificity of 96.6%. …”
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  4. 14444
    “…Methods: In all, 4945 participants (2543 male and 2402 female) were included after excluding subjects using the following criteria: <19 years of age, free T4 level outside the normal range, history of thyroid disease, or incomplete data. …”
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  5. 14445
  6. 14446
  7. 14447
    “…The therapeutic outcome was evaluated one week after M-MSC or PBS injection by awake cystometry and histological analysis. Functionally, LPS/PS insult led to irregular micturition, decreased intercontraction intervals, and decreased micturition volume. …”
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  8. 14448
  9. 14449
    “…In a separate study, we manipulated the activity of nucleus tractus solitarius (NTS) PPG neurons (PPG(NTS)) in awake, freely behaving transgenic Glu-Cre mice implanted with biotelemetry probes and injected with AAV-DIO-hM3Dq:mCherry or AAV-mCherry-FLEX-DTA. …”
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  10. 14450
  11. 14451
    “…Methods: We obtained HRV data from video-electroencephalography recordings in 22 patients presenting PNES (11 pPNES and 11 PNES/ES) in awake, and supine states. We calculated HRV parameters in both time and frequency domains including low frequency (LF) power, high frequency power (HF), LF/HF ratio, square root of the mean of the sum of the squares of differences between adjacent R wave intervals (RMSSD) and the standard deviation of all consecutive R wave intervals (SDNN). …”
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  12. 14452
    “…Here, we explored the transcriptional regulation of the VLPO-Gal neurons in sleep by comparing their transcriptional responses between sleeping mice and those kept awake, sacrificed at the same diurnal time. RESULTS: RNA-sequencing (RNA-seq) analysis was performed on eGFP(+) galanin neurons isolated using laser captured microdissection (LCM) from VLPO. …”
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  13. 14453
    “…The instruction was to do so for 15 min daily when the fetus was awake, from gestational week 28 until birth. In this sub-group analysis, we targeted women born in Sweden giving birth from 32 weeks’ gestation. …”
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  14. 14454
  15. 14455
    “…The incidence and severity of nausea and vomiting were evaluated while patients were awake and throughout the intervals from 0 to 2 h, 2 to 6 h, and 6 to 24 h starting upon arrival at the post-anesthesia care unit. …”
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  16. 14456
    “…Twenty-seven percent of primary and secondary vectors were collected outdoors before 10:00 PM or after 5:00 AM, times when people are usually awake and outdoors. Only two specimens were positive for P. falciparum, one An. aconitus from Phongsaly and one An. minimus from Vientiane Province CONCLUSIONS: The results indicate that people living in rural areas in Laos are constantly exposed to malaria vectors throughout the year and specifically outdoors. …”
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  17. 14457
    “…Surgeons can directly assess whether nerve injury occurs while the patient is awake. However, when patients with multiple osteoporotic vertebral fractures (m-OVFs) receive local anesthesia, fluoroscopy time often has to be increased, the operative time has to be extended, or the operation has to be terminated because of discomfort related to body posture. …”
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  18. 14458
    “…CONCLUSION: The contribution of sex differences for long-term VNS off-target effects on cardiovascular and immune systems was assessed using awake behaving rats. Although VNS did not change the concentration of inflammatory biomarkers in systemic circulation for male and female rats, we observed significant differences in cardiovascular effects of VNS characterized using ECG morphology and HRV analyses.…”
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  19. 14459
    “…We speculate that in the future, patients may be more willing to have minor surgery procedures in the outpatient clinic, with much lower opioid doses, while fully awake, if offered adjunctive virtual reality as a non-pharmacologic analgesic during the procedure. …”
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  20. 14460
    por Nasa, Prashant, Azoulay, Elie, Khanna, Ashish K., Jain, Ravi, Gupta, Sachin, Javeri, Yash, Juneja, Deven, Rangappa, Pradeep, Sundararajan, Krishnaswamy, Alhazzani, Waleed, Antonelli, Massimo, Arabi, Yaseen M., Bakker, Jan, Brochard, Laurent J., Deane, Adam M., Du, Bin, Einav, Sharon, Esteban, Andrés, Gajic, Ognjen, Galvagno, Samuel M., Guérin, Claude, Jaber, Samir, Khilnani, Gopi C., Koh, Younsuck, Lascarrou, Jean-Baptiste, Machado, Flavia R., Malbrain, Manu L. N. G., Mancebo, Jordi, McCurdy, Michael T., McGrath, Brendan A., Mehta, Sangeeta, Mekontso-Dessap, Armand, Mer, Mervyn, Nurok, Michael, Park, Pauline K., Pelosi, Paolo, Peter, John V., Phua, Jason, Pilcher, David V., Piquilloud, Lise, Schellongowski, Peter, Schultz, Marcus J., Shankar-Hari, Manu, Singh, Suveer, Sorbello, Massimiliano, Tiruvoipati, Ravindranath, Udy, Andrew A., Welte, Tobias, Myatra, Sheila N.
    Publicado 2021
    “…The Delphi process yielded strong suggestions for use of systemic corticosteroids for critical COVID-19; awake self-proning to improve oxygenation and high flow nasal oxygen to potentially reduce tracheal intubation; non-invasive ventilation for patients with mixed hypoxemic-hypercapnic respiratory failure; tracheal intubation for poor mentation, hemodynamic instability or severe hypoxemia; closed suction systems; lung protective ventilation; prone ventilation (for 16–24 h per day) to improve oxygenation; neuromuscular blocking agents for patient-ventilator dyssynchrony; avoiding delay in extubation for the risk of reintubation; and similar timing of tracheostomy as in non-COVID-19 patients. …”
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