“…Data were collected across 8 waves between ages 5 years (2003) and 17 years (2015). Associations were tested through cross-lagged models in childhood (5, 7, and 8 years), and in adolescence (10, 12, 13, 15, and 17 years). …”
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“…Technical procedures are often performed on the awake patient, who is herself in an exciting situation during childbirth. …”
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“…However, while general anesthesia abrogates these effects of PDE4 inhibitors, potassium levels decrease to similar extents in both awake as well as in fully anesthetized mice. This suggests that the hypokalemic effects of PDE4 inhibitors occur independently of hypothermia and hypokinesia. …”
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“…PLAIN LANGUAGE SUMMARY: The discovery of the neuropeptide orexin/hypocretin in 1998 and subsequent research during the past 20 years revealed an important role for the lateral hypothalamus (LH) in driving the reward pathway, sleep and awake circuits, decision making and psychotic disorders. …”
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“…Compliance with the current international PA guideline (≥150 min moderate-to-vigorous PA (MVPA) per week, irrespective of bout length) was quantified and variability in average 24h acceleration (indicative of PA volume), awake-time PA levels, sedentary time and accumulation pattern were analysed by linear regression. …”
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“…Both groups then underwent awake surgery and intraoperative DES mapping. DES hotspots (HS(DES)) were also determined in a manner analogous to HS(nTMS). …”
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“…Sleep during lights off was comprised of two states: slow-wave sleep (SWS) and rapid eye movement (REM) sleep. Over all the types of nights, SWS constituted 58% of nighttime behaviour, and REM sleep constituted 18%, with the remaining 24% attributed to being awake. …”
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“…Transcranial magnetic stimulation (TMS), a minimally-invasive, well-tolerated, brain stimulation technique that is performed whilst a person is awake and alert, may improve working memory performance. …”
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“…Controls (n=15, 12 women) were aged 48.5 ±14.5 years with BMI of 26.5 ± 5.4 kg/m(2). The amplitude of the cortisol profile was wider in AI patients, relative to controls, with a higher morning peak and an extended and lower nocturnal nadir. …”
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“…Dextrose water was administered that resulted in improvement of her mentation. She was alert and awake when brought to the hospital but was persistently hypoglycemic despite frequent feeding. …”
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“…The mean ± standard deviation (SD) age at first depressive episode was 38.7 ± 15.9 years, the mean duration of depression 10.6 ± 12.3 years. …”
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“…In the current study, we will present various surgical stages of bladder augmentation in both mice and rats using silk scaffolds and demonstrate techniques for awake and anesthetized cystometry.…”
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“…Case description: A patient with a Barrett oesophageal carcinoma and a resection of the oesophagus with gastric pull-up developed swallowing disorders 6 years and 2 months after the operation. Within 1 year and 7 months two recurrences of the tumor at the anastomosis were found and treated with combined chemoradiotherapy or chemotherapy respectively. 7 years and 9 months after the operation local tumor masses and destruction were present with no ability to orally drink or eat (full feeding by jejunal PEG tube): quality of life was poor, as saliva and mucus were very viscous (pulling filaments) and could not be swallowed and had to be spat out throughout the day and night resulting in short periods of sleep (awaking from the necessity to spit out). …”
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“…However, people who have to do with animals daily have always recognized common mental traits they have with their animals. After 25 years of multi-disciplinary study, nine important mammalian mental homologies have been delineated: (1) All mammals have innate behaviour tendencies which are molded by the individual’s lifetime experiences. (2) They are sentient (that is they feel and have emotions) and consequently are conscious: awake and aware of the world. (3) They all learn in similar ways. (4) They all have to acquire ecological knowledge to live and reproduce. (5) They acquire social knowledge, have a social contract and can develop different traditions and cultures. (6) They have to know about others’ intentions to be social, that is they all have a “theory of mind”: an awareness that others have body/mind beings. (7) They are aware of their own body and feelings, thus they must be self-aware. (8) They are moral agents because they know when they have obeyed the social contract and when not. (9) They have a simple aesthetic sense because they like some things and dislike others. …”
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“…Secondary outcomes included remission of insomnia (Insomnia Severity Index score less than 8), objectively measured and self-reported time awake (ie, total wake time), and the Edinburgh Postnatal Depression Scale score. …”
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“…Here we examined the effects of optogenetic manipulation of CRH BN neurons on the in vivo voiding phenotype and urodynamics in awake mice. We hypothesized that stimulating these neurons at higher frequencies (10–50 Hz) would lead to CRH-dependent alterations in voiding phenotype (i.e., larger voided volumes and longer intermicturition intervals. …”
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“…Recommendations are made for the following head and neck procedures and considerations: primary airway management; high-flow nasal oxygen delivery; jet ventilation for laryngotracheal surgery; awake intubation; transnasal skull base surgery; tracheostomy; and use of personal protective equipment. …”
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“…Children 10 years or older can use masks efficiently when they have been informed beforehand appropriate to their age. …”
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“…SIMPLE SUMMARY: During the deep phases of sleep we do not normally wake up by a thunder, but we nevertheless notice it when awake. The exact same sound gets to our ears and cortex through the thalamus and still, it triggers two very different responses. …”
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“…In a retrospective study, we calculated the average number of embryos isolated from early-pregnancy-stage marmoset monkeys/monthly cycle (embryo retrieval rate; ERR) in an experimental setting, including monthly anesthesia for uterus flushing and frequent (~twice/week) blood sampling in an awake state. Based on this, the monkeys were subdivided into two groups: one with high ERR and one with low ERR. …”
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