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5por Dumet, Christophe, Pugnière, Martine, Henriquet, Corinne, Gouilleux-Gruart, Valérie, Poupon, Anne, Watier, Hervé“…We therefore compiled 1323 Fc variants affecting the affinity for FcRn, which were disclosed in twenty patents. …”
Publicado 2023
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7“…Combining all these mutations is associated with a 32-fold increase of accumulation for the Fc alone, from 23.9 mg/kg fresh weight (FW) to 599.5 mg/kg FW, as well as a twenty-fold increase when fused to a V(H)H that binds EHEC, from 12.5 mg/kg FW tissue to 236.2 mg/kg FW. …”
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8por Boero, Silvia, Morabito, Anna, Banelli, Barbara, Cardinali, Barbara, Dozin, Beatrice, Lunardi, Gianluigi, Piccioli, Patrizia, Lastraioli, Sonia, Carosio, Roberta, Salvi, Sandra, Levaggi, Alessia, Poggio, Francesca, D’Alonzo, Alessia, Romani, Massimo, Del Mastro, Lucia, Poggi, Alessandro, Pistillo, Maria Pia“…PATIENTS AND METHODS: Twenty-five patients with HER-2 overexpressing BC, receiving trastuzumab in a neoadjuvant (NEO) or metastatic (MTS) setting, were genotyped for the FcγRIIIA 158V>F and FcγRIIA 131H>R polymorphisms by a newly developed pyrosequencing assay and by multiplex Tetra-primer-ARMS PCR, respectively. …”
Publicado 2015
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11por Zhang, Donglei, Qin, Jieying, Li, Lin, Su, Guannan, Huang, Guo, Cao, Qingfeng, Kijlstra, Aize, Yang, Peizeng“…Fc receptors are known to have a pivotal role in the initiation and regulation of many immunological and inflammatory processes. …”
Publicado 2018
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