“…Additional recommendations concerning vaccination of egg-allergic persons are discussed. Finally, information on recent licensures and labeling changes is discussed, including expansion of the age indication for Afluria Quadrivalent (IIV4) from ≥18 years to ≥5 years and expansion of the age indication for Fluarix Quadrivalent (IIV4), previously licensed for ≥3 years, to ≥6 months. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Additionally, NP-6A4 (5 μM: 12 h) increased expression of eNOS (sixfold, p < 0.05) and generation of nitric oxide (1.3-fold, p < 0.05) in hCAECs and pre-treatment with PD123319 (20 μM) suppressed this effect partially (65%). Finally, NP-6A4 decreased phosphorylation of Jun-N-terminal kinase, implicated in apoptosis of ECs in atherosclerotic sites. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Brain water content, neurological severity score, western blotting, and immunofluorescence staining were measured at 24 and 72 h following TBI. In the final set of experiments, MFG-E8 siRNA (500 pmol/3 µl), integrin β3 siRNA (500 pmol/3 µl), and PI3K inhibitor LY294002 (5 and 20 µM) were injected i.c.v. and thereafter rats exposed to TBI. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This article summarises the ERG’s review of the company’s evidence submission for Nab-Pac + Gem, and the Appraisal Committee (AC) decision. The final scope issued by NICE listed three comparators: gemcitabine monotherapy (Gem), gemcitabine in combination with capecitabine (Gem + Cap), and a combination of oxaliplatin, irinotecan, leucovorin and fluorouracil (FOLFIRINOX). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The results showed that the mapping trajectory would influence the final mapping results and therefore, there was optimal Matterport configuration for better indoor mapping results. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…More favorable eHealth outcomes were also observed for self-employed European general practitioners (internal practices OR 1.33, 95% CI 1.22-1.45; practices with patients OR 1.10, 95% CI 1.03-1.28). Finally, general practitioners who reported that the number of patients treated in the last 2 years had remained constant (internal practices OR 1.08, 95% CI 1.01-1.17) or increased (practices with patients OR 1.12, 95% CI 1.03-1.22) had a higher propensity toward favorable eHealth usage outcomes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also report evidence of a small gender effect in an action-learning task (F(1,3988)=90.59, P<.001, η(2)(ρ)=.022). Finally, we found a strong negative effect of self-reported age on performance, when controlling for number of plays, in sustained attentional focus (n=1596, F(6,1595)=30.23, P<.001, η(2)=.102), working memory (n=1627, F(6,1626)=19.78, P<.001, η(2)=.068), spatial cognition (n=1640, F(6,1639)=23.74, P<.001, η(2)=.080), and split attention tasks (n=1616, F(6,1615)=2.48, P=.02, η(2)=.009). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The possible internal conversion (IC) and intersystem crossing (ISC) processes of these compounds were investigated. Finally, the relaxed ground state potential energy surface (PES) (S(0)), and singlet (S(n), n = 1–24) and triplet (T(n)) excited state PESs of the TSPP molecule were calculated as function of the dihedral angle (C(α)-C(m)-C(ϕ)-C(ph)) rotation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Inter-curator variations were reviewed and expressed in the final ontologies. Results: Frequency, certainty, degree, and coverage terms with complete agreement among all curators were used as class labels or exact synonyms. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Women were excluded if they immigrated after 1995, had cancer (except non-melanoma skin cancer), had venous thrombosis, or were treated for infertility before entry (final study population included 1 879 227 women). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: Five trials were included in our final analysis - two trials were individual patient randomised-controlled, and the remaining cluster-randomised-crossover trials. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Subsequently, we used multivariate negative binomial generalized linear model regressions to determine whether negative healthcare experiences predicted greater use of these resulting categories. Finally, we stratified our sample based on education level to determine whether the associations between healthcare experiences and eHealth use differed across groups. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We then compared measurements in this material space with theoretical measurements, combining XCOM cross section data with the tungsten anode spectral model using interpolating cubic splines (TASMICS), a one-parameter filter, and a simple detector model, creating a matrix similar to our experimental matrix for the first 20 chemical elements. Finally, we compared the model predictions to Hounsfield unit measurements on three XCT calibration phantoms taken from the literature. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, AR-V7 expression correlated with a unique 59-gene signature in CRPC, including HOXB13, a critical coregulator of AR-V7 function. Finally, AR-V7–negative disease associated with better prostate-specific antigen (PSA) responses (100% vs. 54%, P = 0.03) and overall survival (74.3 vs. 25.2 months, hazard ratio 0.23 [0.07–0.79], P = 0.02) from endocrine therapies (pre-chemotherapy). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: In this cluster randomized trial of 30 primary care practices comprising 6699 patients, there were 1685 patients in the control group (10 practices) and 5014 patients in the intervention group (20 practices). The final sample of practices differed from the original set of randomized practices owing to dropout. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This phenomenon was not observed among ApoE3 and ApoE2 carriers with chronic low-grade inflammation. Finally, a subset of 1761 individuals (66.3%) underwent brain magnetic resonance imaging, and the interaction between ApoE4 and chronic low-grade inflammation was associated with brain atrophy in the temporal lobe (β = –0.88, SE = 0.22; P < .001) and hippocampus (β = –0.04, SE = 0.01; P = .005), after adjusting for confounders. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Participants whose fathers were daily wage workers had greater odds of alcohol use (OR(adj) = 2.89; 95% CI = 1.23-6.79) than those whose parents worked in agriculture, and those whose fathers used alcohol had greater odds of alcohol use than those whose fathers did not use alcohol (OR(adj) = 2.17, 95% CI = 1.40-3.35). Finally, those who had 6-10 and ≥ 11 close friends living in the same village who used alcohol had greater odds of alcohol use (OR(adj) = 8.51, 95% CI = 3.10-23.3; and OR(adj) = 3.84, 95% CI = 1.15-12.77, respectively). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: A Web-based survey of MSM was conducted in August 2017 as a final follow-up of a randomized controlled trial promoting HIV testing in 8 Chinese cities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Detailed interview was available for 20,152 (84.2% participation) births including 275 stillbirths (81.4% participation). In the final regression model, significantly higher odds of stillbirth were documented for deliveries with gestation period of ≤ 8 months (OR 11.36, 95% CI 8.13–15.88), for first born (OR 5.79, 95% CI 4.06–8.26), deferred deliveries wherein a woman was sent back home and asked to come later for delivery by a health provider (OR 5.51, 95% CI 2.81–10.78), and in those with forceful push/pull during the delivery by the health provider (OR 4.85, 95% CI 3.39–6.95). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Key factors that may improve adoption include provider endorsement, greater publicity of efficacious apps, and clear messaging about efficacy and privacy of information. Finally, multifaceted apps that address a range of concerns, from sleep to negative thought patterns, may be best received.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso