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330041por Wenborn, Jennifer, O’Keeffe, Aidan G., Mountain, Gail, Moniz-Cook, Esme, King, Michael, Omar, Rumana Z., Mundy, Jacqueline, Burgess, Jane, Poland, Fiona, Morris, Stephen, Pizzo, Elena, Vernooij-Dassen, Myrra, Challis, David, Michie, Susan, Russell, Ian, Sackley, Catherine, Graff, Maud, Swinson, Tom, Crellin, Nadia, Hynes, Sinéad, Stansfeld, Jacki, Orrell, Martin“…In total, 91% of the activity-based goals set by the pairs taking part in the COTiD-UK intervention were fully or partially achieved by the final COTiD-UK session. Study limitations include the following: Intervention fidelity was moderate but varied across and within sites, and the reliance on primarily proxy data focused on measuring the level of functional or cognitive impairment which may not truly reflect the actual performance and views of the person living with dementia. …”
Publicado 2021
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330042“…Of importance, TET2 knockdown exacerbated brain infarct size and neurological deficits and counteracted the neuroprotective effect of miR-210 inhibition. Finally, the in vitro results demonstrated that the miR-210-TET2 axis regulated pro-inflammatory response in BV2 mouse microglia cell line. …”
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330043por Kubatka, Peter, Kello, Martin, Kajo, Karol, Samec, Marek, Liskova, Alena, Jasek, Karin, Koklesova, Lenka, Kuruc, Tomas, Adamkov, Marian, Smejkal, Karel, Svajdlenka, Emil, Solar, Peter, Pec, Martin, Büsselberg, Dietrich, Sadlonova, Vladimira, Mojzis, Jan“…However, only in lower dose of sumac were significant decreases in the expression of oncogenic miR210 and increase of tumor-suppressive miR145 (miR21, miR22, and miR155 were not changed) observed. Finally, only in lower sumac dose, significant decreases in methylation status of three out of five gene promoters–ATM, PTEN, and TIMP3 (PITX2 and RASSF1 promoters were not changed). …”
Publicado 2020
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330044por Houzelle, Alexandre, Jörgensen, Johanna A., Schaart, Gert, Daemen, Sabine, van Polanen, Nynke, Fealy, Ciarán E., Hesselink, Matthijs K. C., Schrauwen, Patrick, Hoeks, Joris“…Mitonuclear protein balance also associated with heat shock protein 60 (HSP60) protein levels, which were higher in athletes when compared with participants with obesity (p = 0.048) and type 2 diabetes (p = 0.002), indicative for activation of the mitochondrial unfolded protein response. Finally, OPA1, FIS1 and HSP60 correlated positively with aerobic capacity (r = 0.48, p = 0.0001; r = 0.55, p < 0.001 and r = 0.61, p < 0.0001, respectively) and insulin sensitivity (r = 0.40, p = 0.008; r = 0.44, p = 0.003 and r = 0.48, p = 0.001, respectively). …”
Publicado 2020
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330045por Verhulst, Adrien, Normand, Jean-Marie, Lombart, Cindy, Sugimoto, Maki, Moreau, Guillaume“…These measures did not show any significant difference between groups. Finally, we asked them to rate different food products in terms of tastiness, healthiness, sustainability and price. …”
Publicado 2018
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330046“…Retention rate for the follow-up waves— first follow-up wave (T1), second follow-up wave (T2), and final wave (T3)—was high (≥85%). Mean scores of belief accuracy were high for all waves, with scores reflecting low belief in false statements and high belief in true statements; the belief accuracy scale ranged from –1, indicating completely inaccurate beliefs, to 1, indicating completely accurate beliefs (T0 mean 0.75, T1 mean 0.78, T2 mean 0.77, and T3 mean 0.75). …”
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330047por Almoznino, Galit, Zini, Avraham, Kedem, Ron, Protter, Noam E., Zur, Dorit, Abramovitz, Itzhak“…We analyzed the associations between C-reactive protein (CRP) and dental parameters and combined the statistically significant variables to create a dental inflammation score (DIS). This crated a final model with the appropriate weights written as follows: DIS = (periodontal disease × 14) + (the number of teeth that required crowns × 11) + (missing teeth × 75). …”
Publicado 2021
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330048por Ortiz, José Antonio, García-Álvarez, Olga, Amo-Salas, Mariano, Maroto-Morales, Alejandro, Iniesta-Cuerda, María, Fernández-Santos, María del Rocío, Soler, Ana Josefa, Garde, José Julián“…In addition, the administration of melatonin implants before the breeding season was able to minimize the negative effect of low yearling hinds’ liveweight (Weight 1(hind)) on their future reproductive outcomes, as the fertility rates increased by 46% and the calves’ weight increased by 7 kg after the melatonin treatment, regardless of the yearlings’ weight. Finally, when both experimental groups (melatonin and non-treated) were kept separate, higher fertility rates (76.73 ± 7.18% vs. 66.94 ± 7.41%) were observed for the melatonin-treated hinds compared to the non-treated hinds. …”
Publicado 2021
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330049What is the difference between the first and the second/third wave of Covid-19? – German perspectivepor Graichen, Heiko“…Theoretical constructs such as a “Lockdown light” have failed to prove successful. Finally, only a hard Lockdown can bring down numbers sufficiently. …”
Publicado 2021
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330050por Zubair, Mohammad“…In addition to this, the study conducted the following tests: antibiotic sensitivity test, extended-spectrum β-lactamase (ESβL), and methicillin-resistant Staphylococcus aureus (MRSA) production, biofilm formation in 96-well microtiter plates, minimum inhibitory concentration (MIC) determination, the effect of sub-MICs of C. sinensis extract and M. oleifera extract on the viability of test bacteria, and finally, measurement of the inhibition of biofilm. …”
Publicado 2020
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330051por Ayenew, Asteray Assmie“…Of which, 34 were excluded due to duplication, 65 through review of titles and abstracts, and 22 full-text articles were excluded for not reporting the outcome variable and other reasons. Finally, 7 were included to estimate the distribution of ABO and Rh (D) blood groups among pregnant women in Ethiopia. …”
Publicado 2021
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330052por Kohli, Manish, Tan, Winston, Vire, Bérengère, Liaud, Pierre, Blairvacq, Mélina, Berthier, Frederic, Rouison, Daniel, Garnier, George, Payen, Léa, Cousin, Thierry, Joubert, Dominique, Prieur, Alexandre“…Adding hPG(80) levels (score of 1 for patients having hPG(80) levels > 4.5 pM) to the six variables of the IMDC risk model showed a greater and significant difference in OS between the newly defined good-, intermediate- and poor-risk groups (p = 0.0003 compared to p = 0.0076). Finally, when patients with IMDC intermediate-risk group were further divided into two groups based on hPG(80) levels within these subgroups, increased OS were observed in patients with low hPG(80) levels (<4.5 pM). …”
Publicado 2021
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330053por Kassaw, Mesfin Wudu, Abebe, Ayele Mamo, Kassie, Ayelign Mengesha, Abate, Biruk Beletew, Masresha, Seteamlak Adane“…Of the prevalence of child size in year from 2011 to 2016, 17.1% was very small, and 9.8% was small. In the final multivariate logistic regression model, region (AOR = xx), (955%CI = xx), Afar (AOR = 2.44), (95%CI = 1.82, 3.27), Somalia (AOR = 0.73), (95%CI = 0.55, 0.97), Benishangul-Gumz (AOR = 0.48), (95%CI = 0.35, 0.67), SNNPR (AOR = 0.67), (95%CI = 0.48, 0.93), religion, Protestant (AOR = 0.76), (95%CI = 0.60, 0.95), residence, rural (AOR = 1.39), (95%CI = 1.07, 1.81), child sex, female (AOR = 1.43), (95%CI = 1.29, 1.59), birth type, multiple birth during first parity (AOR = 2.18), (95%CI = 1.41, 3.37), multiple birth during second parity (AOR = 2.92), (95%CI = 1.86, 4.58), preparedness for birth, wanted latter child (AOR = 1.26), (95%CI = 1.09, 1.47), fast and rapid breathing (AOR = 1.22), (95%CI = 1.02, 1.45), maternal education, unable to read and write (AOR = 1.46), (95%CI = 1.56, 2.17), and maternal age, 15–19 years old (AOR = 1.86), (95%CI = 1.19, 2.92) associated with proximate low birth weight. …”
Publicado 2021
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330054“…Meanwhile, the correlation between m(6)A regulators and tumor mutational burden (TMB) were tested. Finally, the impacts of IRGs and TME clusters in clinical characteristics and outcomes were revealed. …”
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330055por Stevans, Joel M., Delitto, Anthony, Khoja, Samannaaz S., Patterson, Charity G., Smith, Clair N., Schneider, Michael J., Freburger, Janet K., Greco, Carol M., Freel, Jennifer A., Sowa, Gwendolyn A., Wasan, Ajay D., Brennan, Gerard P., Hunter, Stephen J., Minick, Kate I., Wegener, Stephen T., Ephraim, Patti L., Friedman, Michael, Beneciuk, Jason M., George, Steven Z., Saper, Robert B.“…Adult patients with acute LBP stratified by SBT risk were enrolled in 77 primary care practices in 4 regions across the United States between May 2016 and June 2018 and followed up for 6 months, with final follow-up completed by March 2019. Data analysis was conducted from January to March 2020. …”
Publicado 2021
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330056por Crestani, A, Abdel Wahab, C, Arfi, A, Ploteau, S, Kolanska, K, Breban, M, Bendifallah, S, Ferrier, C, Darai, E“…MRI-AGD was measured retrospectively by a senior radiologist who was blinded to the final diagnosis. Two measurements were made: from the posterior wall of the clitoris to the anterior edge of the anal canal (MRI-AGD-AC), and from the posterior wall of the vagina to the anterior edge of the anal canal (MRI-AGD-AF). …”
Publicado 2021
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330057“…Mobile eHL was related to self-care behaviors as well as knowledge and skills of computers, the internet, and mobile technology, but only had a weak, indirect effect on self-rated health. The final model had adequate goodness-of-fit indexes: chi-square (83)=149.572, P<.001; comparative fit index (CFI)=0.925; root mean square of approximation (RMSEA)=0.057 (90% CI 004-006); chi-square/df=1.082. …”
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330058“…Furthermore, the study aimed to identify any relationships between spelling and editing difficulties and characteristics of individual words. Finally, relationships between successful edits and reading and phonological ability were investigated and specific editing strategies or behaviours identified. …”
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330059por Moro, Arrigo, Blacquière, Tjeerd, Panziera, Delphine, Dietemann, Vincent, Neumann, Peter“…In conclusion, a holistic view including mite adaptations and studies of the same parasite/host populations over time appears overdue to finally understand the mechanisms enabling survival of V. destructor-infested honey bee host colonies.…”
Publicado 2021
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330060por Montaser, Metwally M., El-sharnouby, Mohamed E., EL-Noubi, Gamal, El-Shaer, Heba M., Khalil, Alshimaa A., Hassanin, Mohamed, Amer, Shimaa A., El-Araby, Doaa A.“…After the end of the feeding trial, the fish were challenged with Staphylococcus aureus, and mortalities were noted. The final body weight, total body weight gain, and the total feed intake were quadratically increased in BSRE5 treatment (p < 0.01). …”
Publicado 2021
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