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330721Publicado 2023“…We generated 95% uncertainty intervals (UIs) for final estimates as the 25th and 975th ordered values across 1000 posterior draws, and models were cross-validated for out-of-sample predictive validity. …”
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330722“…In addition, we established in the largest sample to date that Ehler-Danlos Syndrome (EDS) was more likely to occur among autistic females compared to non-autistic females. Finally, we found a higher prevalence of Coeliac’s disease among autistic individuals compared to non-autistic individuals after controlling for sex, ethnicity, country of residence, alcohol use, smoking, and BMI, but these results became non-significant after accounting for family history. …”
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330723por Gliske, Kate, Berry, Katie R, Ballard, Jaime, Schmidt, Clare, Kroll, Elizabeth, Kohlmeier, Jonathan, Killian, Michael, Fenkel, Caroline“…Individuals in the high-acuity+low–self-harm profile completed treatment at a significantly lower rate relative to the other 2 high-acuity profiles (ꭓ(2)(3)=13.4, P=.004). Finally, those in the high-acuity+high–self-harm profile were significantly less likely to disengage early relative to youth in all other profiles (ꭓ(2)(3)=71.12, P<.001). …”
Publicado 2023
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330724por Conti, Renata Maria Consentino, da Silva, Thiago Henrique, da Silva Brandão Guimarães, Iuli Caetano, Bezerra, Helena Viel Alves, Saran Netto, Arlindo, Rodrigues, Paulo Henrique Mazza, Pacheco, José Carlos Guilardi, Zanetti, Marcus Antonio“…Although organic sources of Cu and S added to Mo supplementation had increased the ADG throughout the study, this effect did not reflect in the heavier final BW outcomes for this treatment. In addition, no effect of these treatments was observed on the carcass traits. …”
Publicado 2023
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330725por Paramita, Ni Luh Putu S. P., Agor, Joseph K., Mayorga, Maria E., Ivy, Julie S., Miller, Kristen E., Ozaltin, Osman Y.“…Furthermore, Hispanic patients might have less access to the hospital care compared to non-Hispanic patients when longer hospitalizations are needed due to their diabetes complications. Finally, diabetes complications, which are generally associated with worse COVID-19 outcomes, might be predominantly determining the COVID-19 severity in those infected patients resulting in less demographic differences in COVID-19 hospitalization and in-hospital mortality.…”
Publicado 2023
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330726por Gottschlich, Anna, Gondara, Lovedeep, Smith, Laurie W., Anderson, Jennifer Joy, Cook, Darrel, Krajden, Mel, Lee, Marette, Martin, Ruth Elwood, Melnikow, Joy, Peacock, Stuart, Proctor, Lily, Stuart, Gavin, Franco, Eduardo L., van Niekerk, Dirk, Ogilvie, Gina S.“…Adjusted models demonstrated reductions in referral rates in HPV1 (HR = 0.6, 95% CI: 0.5, 0.7) and HPV2 (HR = 0.7, 95% CI: 0.6, 0.8) relative to BCS by 54 and 72 months post-final HPV screen respectively. INTERPRETATION: Reduced colposcopy referral rates were observed after initial rounds of HPV-based screening. …”
Publicado 2023
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330727por Rassu, Pier Carlo“…No post-operative complications or readmissions were recorded, and no discomfort or recurrence was detected during scheduled visits. Finally, the extent of satisfaction with the overall surgery was recorded immediately and corroborated by most patients during the follow-up period. …”
Publicado 2023
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330728por huang, fei, Nelson, Jennifer, Muralidharan, Charanya, Nakayasu, Ernesto, Yi, Xiaoyan, Eizirik, Decio, May, Sarah, Tersey, Sarah A, Mirmira, Raghavendra G“…Direct interaction of GOLM1 with PD-L1 was observed following immunoblot studies in EndoC-βH1 cells. Finally, analysis of the single cell RNA-Seq database of the Human Pancreas Analysis Program revealed a significant increase in GOLM1 in residual β-cells of individuals with T1D compared to controls. …”
Publicado 2023
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330729“…She was discharged from hospital with resolution of her psychiatric features. Her final diagnosis was APS II. She was started on Fludrocortisone 0.1, Hydrocortisone 20 mg in the morning and 10 mg at night.Clinicians should keep this disease in mind when assessing a patient who has presented with other autoimmune endocrinologic diseases, especially diabetes type I or adrenal insufficiency. …”
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330730“…While gentle Vitamin D supplementation is often recommended in primary hyperparathyroidism, in patients with mild PTH elevations but severe hypercalcemia, CYP24A1 mutations should be considered, and Vitamin D supplements should be avoided. Finally, our case suggests that primary hyperparathyroidism with underlying CYP24A1 mutation may be poorly responsive to cinacalcet. …”
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330731por Palmieri, Michela, Nookaew, Intawat, Jose Schuller-Almeida, Maria, Kim, Ha-Neui, Jospeh, Teenamol E, Manolagas, Stavros C, O'Brien, Charles A, Ambrogini, Elena“…BMP signaling pathways were also unchanged in this scRNA-seq analysis. Finally, using bulk-RNA-seq of vertebral bone and scRNA-seq of myeloid cells, we could not detect changes in the expression of pro-inflammatory cytokines, such as Tnf-α, Il-6, Il1-α, Il-β, Il-4, Il-12, Lif, Il-23, interferon-α, and interferon-β, between WT and E06-scFv mice. …”
Publicado 2023
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330732por Ravel, Guillaume, Chalmey, Clémentine, Berardet, Corentin, Duracher, David, Kurasaki, Haruaki, Tomiyama, Tatsuya, Reid, Patrick, Culler, Michael D“…Blood samples, collected prior to dosing to establish baseline IGF1 levels and 24 hour after the final, seventh AZP-3813 injection, were assayed for total IGF1 content by radioimmunoassay. …”
Publicado 2023
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330733por Madera Marin, Luis Norberto, Rivera-Nieves, Yadiel, Ortiz-Rivera, Monica Alexandra, Rosado-Burgos, Alexandra, Musa Penna, Laurianne El, Medina-Torres, Wilnelia, Sepulveda-Garcia, Luis, Ramirez, Margarita, Gonzalez-Rodriguez, Loida Alejandra, Alvarado, Milliette, Canales, Nicolle“…A presumptive diagnosis of a giant prolactinoma was made for which cabergoline therapy was initiated. Final pathologic diagnosis revealed a paraganglioma. …”
Publicado 2023
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330734por Ortiz-Rivera, Monica Alexandra, Madera Marin, Luis Norberto, Rosado-Burgos, Alexandra, Musa Penna, Laurianne El, Medina-Torres, Wilnelia, Sepulveda-Garcia, Luis Ruben, Gonzalez-Rodriguez, Loida Alejandra, Ramirez-Vick, Margarita, Alvarado-Santiago, Milliette, Grana Santini, Alberto Javier, Feliciano-Emmanuelli, Melba“…Dexamethasone 0.25 mg was then added at bedtime and the patient was finally able to achieve restoration of menses, resolution of salt cravings and hormonal profile control with decreases in renin to 23.02 pg/mL, androstenedione to < 0.30 ng/mL, TT to 11 ng/dL and 17-OHprog to 3.15 ng/mL. …”
Publicado 2023
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330735por Mayer, Julian Martinez, Hackbartt, Martina, Garcia, Lucia Iglesias, Vishnopolska, Sebastian, Zaiat, Jonathan, Perticarari, Catalina, Braslavsky, Debora Giselle, Keselman, Ana Claudia, Bergada, Ignacio, Marino, Roxana, Ramirez, Pablo, Garrido, Natalia Perez, Ciaccio, Marta, Di Palma, María Isabel, Belgorosky, Alicia, Forclaz, Veronica, Benzrihen, Maria Gabriela, D´Amato, Silvia, Rojas, Gabriela Patricia, Miras, Mirta, Alejandra, Paez Nuñez, Castro, Laura, Alonso, Guillermo Francisco, Gil, Susana Mallea, Ballarino, Carolina, Latorre Villacorta, Laura Viviana, Figueroa, Verónica, Morin, Analia, Guntsche, Zelmira, Lee, Hane, Lee, Eugene, Song, Yongjun, Hyun, Seong-In, Marti, Marcelo, Perez-Millan, Maria Ines“…Our results highlight the importance of an exhaustive analysis of candidate variants, which contemplates splicing variants as well as copy number variation (CNVs). Finally, these findings further support the hypothesis that CPHD is highly heterogeneous and may be frequently oligogenic, underlying a very complex pathogenesis for genetic diagnosis. …”
Publicado 2023
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330736por Shankar, Kripa, Varshney, Salil, Gupta, Deepali, Singh, Omprakash, Ogden, Sean B, Osborne-Lawrence, Sherri, Metzger, Nathan P, Richard, Corine P, Marc Zigman, Jeffrey“…A 20% glucose solution was simultaneously infused at a variable rate to achieve hypoglycemia (35–45 mg/dL) during the final 30 min. Blood glucose was measured via tail nicks every 5 min. …”
Publicado 2023
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330737por Van Vu, Sy, Nguyen, Anh-Thu, Cao Tran, Anh-Thi, Thi Le, Viet-Ha, Lo, Tien Nu Hoang, Ho, Thi H., Pham, Nguyet. N. T., Park, In, Vo, Khuong Quoc“…To create the nanoarrays, a three-step method was employed, which involved the controlled synthesis of gold nanostars, covering them with a silver layer (AuNSs-FS@Ag and AuNSs-CTAB@Ag), and finally self-assembling the AuNS@Ag core-shelled nanoparticles via the liquid/liquid self-assembly method. …”
Publicado 2023
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330738por Holleyman, Richard James, Barnard, Sharmani, Bauer-Staeb, Clarissa, Hughes, Andrew, Dunn, Samantha, Fox, Sebastian, Newton, John N., Fitzpatrick, Justine, Waller, Zachary, Deehan, David John, Charlett, Andre, Gregson, Celia L., Wilson, Rebecca, Fryers, Paul, Goldblatt, Peter, Burton, Paul“…This methodology is applied at the individual level, rather than the population level to provide a better understanding of the impact of a positive COVID-19 test on the mortality of groups with different vulnerabilities conferred by sociodemographic and health characteristics. Finally, we apply the mortality displacement estimates to adjust estimates of excess mortality using a “ball and urn” model. …”
Publicado 2023
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330739por Lv, Lu, Cui, En-Hai, Wang, Bin, Li, Li-Qin, Hua, Feng, Lu, Hua-Dong, Chen, Na, Chen, Wen-Yan“…BACKGROUND: Acute lung injury (ALI) and its final severe stage, acute respiratory distress syndrome, are associated with high morbidity and mortality rates in patients due to the lack of effective specific treatments. …”
Publicado 2023
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330740“…Results: According to the inclusion and exclusion criteria, 172 patients with grade 2–3 astrocytoma were finally included in the study, and a total of 44 patients met the diagnosis of DAG-G. …”
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