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331161por Parker, Elizabeth Kumiko, Ashley, Mellisa Anne, Moretti, Courtney, Harris, Deanne Maree, Stefoska-Needham, Anita“…METHODS: A semi-structured question guide was developed by researchers to elicit information from six virtual focus groups consisting of a purposive sample of practising dietitians and student dietitians enrolled in their final year of an Australian tertiary accredited dietetic program. …”
Publicado 2022
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331162por Fan, Yuanchan, Wang, Jie, Yu, Kejun, Zhang, Wende, Cai, Zongbing, Sun, Minghui, Hu, Ying, Zhao, Xiao, Xiong, Cuiling, Niu, Qingsheng, Chen, Dafu, Guo, Rui“…Furthermore, expression clustering analysis demonstrated that the majority of genes encoding virulence factors such as ricin B lectins and polar tube proteins displayed apparent upregulation, whereas a few virulence factor-associated genes such as hexokinase gene and 6-phosphofructokinase gene presented downregulation during the fungal infection. Finally, the expression trend of 14 DEGs was confirmed by RT-qPCR, validating the reliability of our transcriptome datasets. …”
Publicado 2022
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331163por Leonelli, Cristina, Turk, Janez, Poggetto, Giovanni Dal, Catauro, Michelina, Traven, Katja, Mauko Pranjić, Alenka, Ducman, Vilma“…However, in terms of impact on abiotic depletion of elements and impact on ozone layer depletion, the increase is relatively more significant (11% and 18%, respectively); 2) replacing some parts of fly ash with metakaolin also results in relatively higher environmental footprint (increase of around 1%–4%, while the impact on abiotic depletion of elements increases by 14%); and finally, 3) firing at 1,000°C contributes significantly to the environmental footprint of alkali-activated foams. …”
Publicado 2022
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331164Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studiespor Solmi, Marco, Radua, Joaquim, Olivola, Miriam, Croce, Enrico, Soardo, Livia, Salazar de Pablo, Gonzalo, Il Shin, Jae, Kirkbride, James B., Jones, Peter, Kim, Jae Han, Kim, Jong Yeob, Carvalho, Andrè F., Seeman, Mary V., Correll, Christoph U., Fusar-Poli, Paolo“…Median age at onset for specific mental disorders mapped on a time continuum, from phobias/separation anxiety/autism spectrum disorder/attention deficit hyperactivity disorder/social anxiety (8-13 years) to anorexia nervosa/bulimia nervosa/obsessive-compulsive/binge eating/cannabis use disorders (17-22 years), followed by schizophrenia, personality, panic and alcohol use disorders (25-27 years), and finally post-traumatic/depressive/generalized anxiety/bipolar/acute and transient psychotic disorders (30-35 years), with overlap among groups and no significant clustering. …”
Publicado 2021
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331165por Costentin, Charlotte, Piñero, Federico, Degroote, Helena, Notarpaolo, Andrea, Boin, Ilka F., Boudjema, Karim, Baccaro, Cinzia, Podestá, Luis G., Bachellier, Philippe, Ettorre, Giuseppe Maria, Poniachik, Jaime, Muscari, Fabrice, Dibenedetto, Fabrizio, Duque, Sergio Hoyos, Salame, Ephrem, Cillo, Umberto, Marciano, Sebastian, Vanlemmens, Claire, Fagiuoli, Stefano, Burra, Patrizia, Van Vlierberghe, Hans, Cherqui, Daniel, Lai, Quirino, Silva, Marcelo, Rubinstein, Fernando, Duvoux, Christophe“…The R3-AFP model including last available pre-LT AFP value outperformed the original R3 model only based on explant features. The final R3-AFP scoring system provides a robust framework to design post-LT surveillance strategies, protocols, or adjuvant therapy trials, irrespective of criteria used to select patients with HCC for LT.…”
Publicado 2022
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331166por Marks, David I, Kirkwood, Amy A, Rowntree, Clare J, Aguiar, Melanie, Bailey, Katharine E, Beaton, Brendan, Cahalin, Paul, Castleton, Anna Z, Clifton-Hadley, Laura, Copland, Mhairi, Goldstone, Anthony H, Kelly, Richard, Lawrie, Emma, Lee, SooWah, McMillan, Andrew K, McMullin, Mary Frances, Menne, Tobias F, Mitchell, Rachel J, Moorman, Anthony V, Patel, Bela, Patrick, Pip, Smith, Paul, Taussig, David, Yallop, Deborah, Alapi, Krisztina Zuborne, Fielding, Adele K“…Nine patients were excluded from the final analysis due to misdiagnosis (standard of care n=4, standard of care plus rituximab n=5). …”
Publicado 2022
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331167por Jones, Robin L., Ravi, Vinod, Brohl, Andrew S., Chawla, Sant, Ganjoo, Kristen N., Italiano, Antoine, Attia, Steven, Burgess, Melissa A., Thornton, Katherine, Cranmer, Lee D., Cheang, Maggie Chon U., Liu, Lingyun, Robertson, Liz, Adams, Bonne, Theuer, Charles, Maki, Robert G.“…An interim analysis to determine the final sample size was conducted after enrollment of 123 patients. …”
Publicado 2022
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331168por Arthur, Dhipak, John, Deepa, Fleming, Jude Joseph, Rebekah, Grace, Gowri, Mahasampath, John, Sheeja Susan“…Many of the systemic risk factors for retinal vein occlusions are found to be associated with elevation of serum homocysteine levels, which may be part of a final common pathway in bringing about a state of accelerated atherosclerosis, leading to CRVO or HCRVO. …”
Publicado 2022
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331169por Miano, Carmen, Morselli, Alessandra, Pontis, Francesca, Bongiovanni, Chiara, Sacchi, Francesca, Da Pra, Silvia, Romaniello, Donatella, Tassinari, Riccardo, Sgarzi, Michela, Pantano, Elvira, Ventura, Carlo, Lauriola, Mattia, D’Uva, Gabriele“…Similar results were obtained by the analysis of basal-like/triple-negative breast cancer cellular models, MDA-MB-468 and MDA-MB-231 cells, in which NRG1β induced anchorage-independent cell growth that in turn was prevented or reduced by the simultaneous administration of anti-HER2 neutralizing antibodies. Finally, the ability of pertuzumab in suppressing NRG1β-induced 3D growth was also evaluated and confirmed in MCF10A engineered with HER2-overexpression. …”
Publicado 2022
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331170por Lo, Yu Tung, Lim, Vivian Yujing, Ng, Melissa, Tan, Ya Hwee, Chiang, Jianbang, Chang, Esther Wei Yin, Chan, Jason Yongsheng, Poon, Eileen Yi Ling, Somasundaram, Nagavalli, Bin Harunal Rashid, Mohamad Farid, Tao, Miriam, Lim, Soon Thye, Yang, Valerie Shiwen“…Results: A total of 75 patients who received chemoimmunotherapy were included in the final analysis. For NLR, OS was longer with higher pre-chemoimmunotherapy (post-steroid) NLR (dichotomized at NLR ≥ 4.0, HR 0.42, 95% CI: 0.21–0.83, p = 0.01) only. …”
Publicado 2022
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331171“…All patients had minimum 1-year postoperative PROMIS scores and minimum 3-month postoperative radiographs. Preoperative, final postoperative and change in PROMIS scores from 6 domains (physical function, pain interference, pain intensity, global physical and mental health, and depression) were compared between the isolated bunion and bunion with hammertoe correction groups. …”
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331172“…The R statistical software program was used to conduct standard meta-analysis. Results: We finally obtained 48 studies with 5,211 patients included in this review after screening. …”
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331173“…Of note, the MBI scores of the study group at discharge and 1 month, 3 months, and 6 months after operation were higher compared to those of the control group (P < 0.05). Finally, we compared the scores of life quality. Before nursing, there exhibited no significant difference (P > 0.05). …”
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331174por Montalbán, Ana, Sánchez, Cristian Jesús, Hernández, Fuensanta, Schiavone, Achille, Madrid, Josefa, Martínez-Miró, Silvia“…The average number of days for the larvae to start pupating was lower in those reared on the HS-LP and LS-HP diets (88.90 and 91.00 days, respectively) than those on the MS-MP diet (120.09 days) (p < 0.001). The final individual weight was higher (p < 0.001) in larvae of the LS-HP group (168.69 mg) compared to those of the other groups (100.29 and 112.99 mg for HS-LP and MS-MP, respectively). …”
Publicado 2022
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331175Analysis of HFMD Transmissibility Among the Whole Population and Age Groups in a Large City of Chinapor Li, Peihua, Rui, Jia, Niu, Yan, Xie, Fang, Wang, Yifang, Li, Zhuoyang, Liu, Chan, Yu, Shanshan, Huang, Jiefeng, Luo, Li, Deng, Bin, Liu, Weikang, Yang, Tianlong, Li, Qun, Chen, Tianmu“…Intra-group transmissibility was strongest in the 0–2 years age group (median: 1.787, range: 0–9.146), followed by Group 1 to Group 2 (median: 0.287, range: 0–1.988) and finally Group 1 to Group 3 (median: 0.287, range: 0–1.988). …”
Publicado 2022
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331176“…Subsequently, foam cells were treated with different concentrations (0.01 µg/mL, 0.1 µg/mL, 0.5 µg/mL, 1 µg/mL, 5 µg/mL and 10 µg/mL) of rapamycin or paclitaxel for 48 hours, to measure cytokine, cell viability and proliferation by ELISA and MTT, respectively. Finally, viability and proliferation were measured by MTT after the foam cells were treated with 1 µg/mL rapamycin or paclitaxel combined with cytokine antibody for 48 hours. …”
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331177por Luo, Zhenwu, Health, Sonya L., Li, Min, Yang, Hyojik, Wu, Yongxia, Collins, Michael, Deeks, Steven G., Martin, Jeffrey N., Scott, Alison, Jiang, Wei“…In contrast, lipid A from B. fungorum and S. marcescens showed structures more consistent with canonical TLR4 agonists stemming from proinflammatory bacterial strains. Finally, intraperitoneal (i.p.) injection of inactivated B. fungorum and S. marcescens but not P. myrsinacearum resulted in cell apoptosis in mesenteric lymph nodes of C57BL/6 mice in vivo. …”
Publicado 2022
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331178por Wainstein, Marina, MacDonald, Samual, Fryer, Daniel, Young, Kyle, Balan, Valeria, Begum, Husna, Burrell, Aidan, Citarella, Barbara Wanjiru, Cobb, J. Perren, Kelly, Sadie, Kennon, Kalynn, Lee, James, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Semple, Malcolm G., Strudwick, Samantha, Webb, Steven A., Rossignol, Patrick, Claure-Del Granado, Rolando, Shrapnel, Sally“…A total of 75,670 patients were included in the final analysis cohort. Median length of admission was 12 days (interquartile range [IQR] 7, 20). …”
Publicado 2022
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331179por Ungefroren, Hendrik, Thürling, Isabel, Färber, Benedikt, Kowalke, Tanja, Fischer, Tanja, De Assis, Leonardo Vinícius Monteiro, Braun, Rüdiger, Castven, Darko, Oster, Henrik, Konukiewitz, Björn, Wellner, Ulrich Friedrich, Lehnert, Hendrik, Marquardt, Jens-Uwe“…Of note, stimulation with TGFβ1 induced a shift in parental PANC-1 cultures towards a more extreme M and invasive phenotype, while exposing the cells to a combination of the proinflammatory cytokines IFNγ, IL1β and TNFα (IIT) elicited a shift towards a more E and less invasive phenotype resembling a MET-like process. Finally, we show that the actions of TGFβ1 and IIT both converge on regulating the ratio of the small GTPase RAC1 and its splice isoform, RAC1b. …”
Publicado 2022
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331180“…In regard to the treatment results of the two groups, after admission to the hospital for radio frequency, ablation, and adjustment of drug treatment to reprogram control, the patients did not reappear to have CRT-D misidentification and misdischarged. Finally, we compared the diagnosis time of VT/VE events. …”
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