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  1. 331241
    “…With application of fuzzy margin obtained from first-level fuzzy, overlapped rectal volumes and corresponding NTCP values were fuzzified in second-level fuzzy using rectal volume variations. The final risk factor (RF) of rectum was qualitatively assessed and found clinically acceptable for each fractional volume of irradiated to total volume and relevant NTCP values. …”
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    Normal Tissue Risk Estimation Using Biological Knowledge-Based Fuzzy Logic in Volumetric Modulated Arc Therapy of Prostate Cancer: Rectum
  2. 331242
    “…To evaluate the two models’ (CTVI(MCD U‐Net), CTVI(U‐Net)) performance, we used fivefold cross‐validation for the training and validation sets. To test the final model performances for both approaches, we applied the test set to each trained model and averaged the test prediction results from the five trained models to acquire the mean test result (bagging) for each approach. …”
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    A deep learning method for translating 3DCT to SPECT ventilation imaging: First comparison with (81m)Kr‐gas SPECT ventilation imaging
  3. 331243
    “…Methods: We conducted a study at the Jinling Hospital from January 2015 to June 2020, in which a total of 140 patients were finally enrolled. Results: Voriconazole doses were adjusted in 44 patients due to abnormal voriconazole drug concentration or side effects, 32 patients reduced the dose and 8 patients increased the dose. …”
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    Therapeutic drug monitoring and safety evaluation of voriconazole in the treatment of pulmonary fungal diseases
  4. 331244
    “…Hard copies of the questionnaires were distributed in January and February 2019 and in total 402 completed questionnaires were collected; questionnaires which included >20% of missing or incomprehensible responses were excluded from the database, resulting in 398 questionnaires being included in the final database. The study identified a number of socio-demographic factors associated with owners’ beliefs and attitudes that directly affect care provided to pet cats, e.g., the owner’s occupation has been identified as a factor associated with owner perception of certain cats’ behaviours, e.g., a cat brushing against the owner as food requests by their animal (Chi-Square 7.711 (df1), exact p = 0.006). …”
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    Association between Socio-Demographic Factors and Owners’ Beliefs and Attitudes to Pet Cats Fundamental Dietary and Physical Exercise Needs, in City of Belfast
  5. 331245
    “…However, the 1.37% LA group significantly improved the final body weight and specific growth rate (SGR) (p < 0.05) of alevins. …”
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    Effect of Dietary Linoleic Acid (18:2n-6) Supplementation on the Growth Performance, Fatty Acid Profile, and Lipid Metabolism Enzyme Activities of Coho Salmon (Oncorhynchus kisutch) Alevins
  6. 331246
    “…DTI indices including FA value and ADC value were correlated with the preoperative score, final follow-up score and improvement percentage. …”
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    Can preoperative cervical spinal diffusion tensor imaging (DTI) indices predict surgical outcomes in patients with Hirayama disease? A retrospective cohort study
  7. 331247
    “…In total, 10,850 persons were surveyed, and 10,419 participants were incorporated into the final analysis after removing invalid questionnaires. …”
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    Primary Health Institutions and Service Quality in China: Implications for Health Policy
  8. 331248
    por HUANG, Youfang, LIU, Jun, HUANG, Xiaojia
    Publicado 2022
    “…The developed method also showed wide linear ranges and good precision. Finally, the established NH(2)-CNTs@M/MSPE-HPLC-DAD approach was applied to measure trace levels of PAs in cereals and vegetables, and good fortified recoveries (72.3% to 113%) and repeatability (RSDs below 10%) were obtained. …”
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    “一锅法”制备氨基碳纳米管功能化磁性纳米粒子及其在谷物和蔬菜中苯氧羧酸类除草剂测定中的应用
  9. 331249
    “…FINDINGS: Of 185 individuals who were randomly assigned to AZD1222, we included 91 individuals who were baseline seropositive and 58 who were baseline seronegative, in the final analysis. In the seropositive group, there was little change of anti-S IgG (and anti-RBD IgG) or neutralising antibody (NAb) titres at day 42 compared with at day 28. …”
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    Durability of ChAdOx1 nCoV-19 (AZD1222) vaccine and hybrid humoral immunity against variants including omicron BA.1 and BA.4 6 months after vaccination (COV005): a post-hoc analysis of a randomised, phase 1b–2a trial
  10. 331250
    “…BNP), calcium, renal replacement therapy (RRT), and partial thromboplastin time (PTT) were the top 22 features of the NN model with the greatest impact. Finally, after hyperparameter optimization, SHAP plots were employed to make the NN-based model interpretable with an analytical description of how the constructed model visualizes the prediction of death. …”
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    Interpretable machine learning for 28-day all-cause in-hospital mortality prediction in critically ill patients with heart failure combined with hypertension: A retrospective cohort study based on medical information mart for intensive care database-IV and eICU databases
  11. 331251
    “…It is worth noting that the fluorescence quantitative expression level showed that the PdERF24 gene was extremely significant at −30 °C, suggesting that this gene may play an important role in the response of almond dormancy to ultralow temperature freezing stress. Finally, we identified 7424 and 6971 target genes based on AP2 and ERF/DREB DNA-binding sites, respectively. …”
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    Genome-Wide Analysis of the Almond AP2/ERF Superfamily and Its Functional Prediction during Dormancy in Response to Freezing Stress
  12. 331252
    “…Interestingly, when checkpoint gene expression (CD276, CTLA-4, and PDCD-1) and tumor immune dysfunction and rejection (TIDE) scores are considered, high-risk patients may respond better to immunotherapy. Finally, most drugs commonly used in preclinical and clinical systemic therapy for HCC, such as 5-fluorouracil, gemcitabine, paclitaxel, imatinib, sunitinib, rapamycin, and XL-184 (cabozantinib), were found to be more efficacious in the low-risk group; erlotinib, an exception, was more efficacious in the high-risk group. …”
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    Cuproptosis-related long non-coding RNAs model that effectively predicts prognosis in hepatocellular carcinoma
  13. 331253
    “…Next, primary univariate logistic analyses explored possible associations with OHI seeking. Finally, using data from those seeking OHI, exploratory univariate analyses sought possible associations with eHealth literacy. …”
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    Online Health Information Seeking and eHealth Literacy Among Spanish Language–Dominant Latino Adults Receiving Care in a Community Clinic: Secondary Analysis of Pilot Randomized Controlled Trial Data
  14. 331254
    “…Step 2, a phenotype-driven comprehensive analysis yielded additional diagnostic findings for another 28 cases (1.7%; 28/1618). In the final step 3, data reanalyses based on new phenotypes and/or clinical requests found molecular diagnosis in 14 additional cases (0.9%; 14/1618). …”
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    Application of exome sequencing for prenatal diagnosis of fetal structural anomalies: clinical experience and lessons learned from a cohort of 1618 fetuses
  15. 331255
    “…RESULTS: Of the patients initially screened, 7 patients fulfilled criteria and were included in the final analysis. The age range was 45-73 with 4 female patients and 3 male patients. …”
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    ODP171 Choosing GLP-1RA Over Insulin for Patients with Type 2 Diabetes and Severe Hyperglycemia
  16. 331256
    “…The mean baseline potassium was 4.2 (SD 0.46); one (3.2%) patient had baseline hypokalemia (K < 3.5 mEql/dL). The mean final PRA was 4.78 (SD 5.64) ng/ml/h. The median (IQR) MRA dose required to achieve unsuppressed PRA was 75 (50 to 200) mg. …”
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    PSUN53 Using Renin Activity to Guide Mineralocorticoid Receptor Antagonist Therapy in Patients with Low-Renin Hypertension
  17. 331257
    “…During embryogenesis, both the superior and inferior parathyroid glands detach from their pharyngeal origin and migrate towards their final location, posteriorly to the thyroid gland. …”
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    ODP075 A Rare Case of Intrathymic Parathyroid Adenoma
  18. 331258
    “…FINDINGS: Between April 29 and July 28, 2021, 54 923 eligible individuals were enrolled in the study, with final group allocations (following withdrawals) of 26 123 (52·6%) participants in the DCT group and 23 500 (47·4%) in the self-isolation group. …”
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    Daily use of lateral flow devices by contacts of confirmed COVID-19 cases to enable exemption from isolation compared with standard self-isolation to reduce onward transmission of SARS-CoV-2 in England: a randomised, controlled, non-inferiority trial
  19. 331259
    “…Furthermore, cerebellar and supplementary motor area activation by MC4R agonism are associated with increased sexual arousal and sexual motor imagery respectively. Finally, MC4R agonism enhanced functional connectivity between key limbic structures which can be disrupted in HSDD. …”
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    RF01 | PMON43 Melanocortin-4 Receptor Agonism Enhances Sexual Brain Processing in Women with Hypoactive Sexual Desire Disorder
  20. 331260
    por Hashmi, Hiba, Fish, Lisa
    Publicado 2022
    “…We report a case where IPSS testing and the size of the adenoma on MRI were misleading in determining the final diagnosis, prompting us to challenge the existing guidelines. …”
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    PMON93 Adenoma Size & Inferior Petrosal Sinus Sampling in Cushing's Disease Diagnosis - Smoke & Mirrors?
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