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331401por Deluc, Laurent G, Grimplet, Jérôme, Wheatley, Matthew D, Tillett, Richard L, Quilici, David R, Osborne, Craig, Schooley, David A, Schlauch, Karen A, Cushman, John C, Cramer, Grant R“…In particular, mRNA expression patterns of transcription factors, abscisic acid (ABA) biosynthesis, and calcium signaling genes identified candidate factors likely to participate in the progression of key developmental events such as véraison and potential candidate genes associated with such processes as auxin partitioning within berry cells, aroma compound production, and pathway regulation and sequestration of flavonoid compounds. Finally, analysis of sugar metabolism gene expression patterns indicated the existence of an alternative pathway for glucose and triose phosphate production that is invoked from véraison to mature berries. …”
Publicado 2007
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331402por Johanson, Conrad E, Duncan, John A, Klinge, Petra M, Brinker, Thomas, Stopa, Edward G, Silverberg, Gerald D“…CSF recycling between subarachnoid space, brain and ventricles promotes interstitial fluid (ISF) convection with both trophic and excretory benefits. Finally, CSF reabsorption via multiple pathways (olfactory and spinal arachnoidal bulk flow) is likely complemented by fluid clearance across capillary walls (aquaporin 4) and arachnoid villi when CSFP and fluid retention are markedly elevated. …”
Publicado 2008
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331403por Sivamani, Raja K, Pullar, Christine E, Manabat-Hidalgo, Catherine G, Rocke, David M, Carlsen, Richard C, Greenhalgh, David G, Isseroff, R. Rivkah“…Burn wound injury in excised human skin also rapidly up-regulates the intra-epithelial expression of the epinephrine synthesizing enzyme phenylethanolamine-N-methyltransferase, and tissue levels of epinephrine rise dramatically (15-fold) in the burn wounded tissue (values of epinephrine expressed as pg/ug protein ± standard error of the mean: unburned control, 0.6 ± 0.36; immediately postburn, 9.6 ± 1.58; 2 h postburn, 3.1 ± 1.08; 24 h post-burn, 6.7 ± 0.94). Finally, using an animal burn wound model (20% body surface in mice), we found that systemic treatment with βAR antagonists results in a significant increase (44%, 95% CI 27%–61%, p < 0.00000001) in the rate of burn wound re-epithelialization. …”
Publicado 2009
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331404por Kalache, Alexandre“…In March 2006 a core group of cities met in Vancouver to finalize the project protocol and within the next few months WHO and its partners from 33 cities from 22 countries implemented the qualitative research that led to the WHO Age friendly Cities Guide launched in 1 October 2007. …”
Publicado 2009
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331405“…Children were 11-18 years of age of both sexes. The final report is, however, only on 11090 schoolchildren from Mumbai and Delhi as data from Kolkata was restricted both in numbers and objectives and could not be included for comparison. …”
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331406por Neubauer, Horst, Kaiser, Andreas FC, Endres, Heinz G, Krüger, Jan C, Engelhardt, Andreas, Lask, Sebastian, Pepinghege, Fenena, Kusber, Andreas, Mügge, Andreas“…On including prasugrel in the therapy plan, we were finally able to eliminate thienopyridine low response. …”
Publicado 2011
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331407“…MODEL: These elements informed and influenced the ongoing development of the evolving INTERLINKS model which is currently being validated by National Expert Panels and a European Sounding Board. During the final cyclical phase of the project the web-based model will cover all themes and key-issues necessary to describe and analyse LTC systems, including practice examples. …”
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331408“…In each climatic region, three vegetation sites were selected for ecological information; the mean values of density, basal cover, and the importance value index from all sites of each region were used to interpret the final data. Ethnomedicinal uses were collected from informants of adjacent villages. …”
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331409por Gardner, Lauren, Malik, Rohit, Shimizu, Yoshiko, Mullins, Nicole, ElShamy, Wael M“…The TopoGen decatenation kit was used to measure TopoIIα decatenation activity. Finally, a comet assay and metaphase chromosome spread were used to detect chromosome breakage and changes in chromosome condensation or numbers, respectively. …”
Publicado 2011
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331410“…These separate systems were integrated into a coding framework model called the communication-based influence components model. Finally, the third analysis assessed the relationships between intervention adherence and behavioral outcomes. …”
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331411por Hollenbeak, Christopher S., Nikkel, Lucas E., Schaefer, Eric W., Alemao, Evo, Ghahramani, Nasrollah, Raman, Jay D.“…METHODS: The sample was limited to non-HMO patients aged 65 years or older who were diagnosed with a first primary RCC (SEER site recode 59, kidney and renal pelvis) between 1995 and 2002. Our final sample included 4,938 patients with RCC and 9,876 non-HMO noncancer comparison group cases without chronic renal disease drawn from the SEER 5% Medicare sample and matched by a propensity score calculated from age, gender, race/ethnicity, and comorbidities. …”
Publicado 2011
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331412“…After chart review we finally identified 221 patients meeting the definition of HAP/VAP. …”
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331413“…How can the intermediate goal of industry (patient welfare) serve the purpose of the final goal of academia is the basic struggle for conscientious research institutions /associations. …”
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331414“…External review by Ontario practitioners was obtained through a mailed survey. Final approval of the original guideline report was obtained from the Practice Guidelines Coordinating Committee. …”
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331415por Duthoit, Guillaume, Fressart, Véronique, Hidden-Lucet, Françoise, Simon, Françoise, Kattygnarath, Darouna, Charron, Philippe, Himbert, Caroline, Aouate, Philip, Guicheney, Pascale, Lecarpentier, Yves, Frank, Robert, Hébert, Jean-Louis“…In BrS group III, 8/10 patients (16% of BrS patients) finally fulfilled international ESC/WHF 2000 ARVD/C criteria and 5/10 (10% of BrS patients) fulfilled BrS diagnostic criteria. …”
Publicado 2012
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331416por Hemmings, K.E., Maruthini, D., Vyjayanthi, S., Hogg, J.E., Balen, A.H., Campbell, B.K., Leese, H.J., Picton, H.M.“…Oocytes were cultured for 24 h and the depletion/appearance of amino acids was measured during the final 6 h of IVM. Amino acid turnover was analysed in relation to oocyte meiotic progression, patient age, disease aetiology and controlled ovarian stimulation regime. …”
Publicado 2013
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331417por Deshpande, Alina, Brown, Mac, Castro, Lauren, Daniel, William B., Generous, Eric N., Hengartner, Andrea, Margevicius, Kristen, Taylor-McCabe, Kirsten“…Additionally, evaluate data integration algorithms useful for a global disease surveillance system through a review of scientific literature. Finally, validate the top-ranked data streams by application of specific historical outbreaks to determine whether the data streams are capable of providing early warning or detection of the particular disease before it became a large outbreak. …”
Publicado 2013
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331418por Quintero, Gabriel C“…At the clinical level, the pattern of polydrug consumption is a phenomenon of considerable frequency. Finally, as a complement at the end, an updated summary is included about the role of glutamate in other neuropsychiatric disorders (for example, mood disorders, schizophrenia, and others).…”
Publicado 2013
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331419“…Primary outcome measure All-cause mortality at final follow-up. Results Eighteen articles reporting on 16 primary clinical trials that included 4190 adults in critical or intensive care with sepsis, severe sepsis, or septic shock. …”
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331420“…Completed questionnaires that were included in the final analysis numbered 321 (51.9%). Age and gender had no statistically significant association with increased awareness of screening options (p = 0.526 and p = 0.2). …”
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