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331461por Bentea, Eduard, Moore, Cynthia, Villers, Agnès, Churchill, Madeline J, Hood, Rebecca L, Deneyer, Lauren, Verbruggen, Lise, Albertini, Giulia, Sato, Hideyo, Ris, Laurence, Meshul, Charles K, Massie, Ann“…Electrophysiological measures of corticostriatal transmission were obtained by recording the amplitude of field excitatory postsynaptic potentials (fEPSPs) after stimulation of corticostriatal fibers. Finally, grooming behavior was compared between xCT-/- and xCT+/+ littermates. …”
Publicado 2018
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331462por Sigvard, Anne, Tangmose, Karen, Bojesen, Kirsten Borup, Jessen, Kasper, Nielsen, Mette Ødegaard, Fuglø, Dan, Jensen, Lars Thorbjørn, Rostrup, Egill, Glenthøj, Birte“…To account for PVE and other factors the image data will be co-registered with T1-weighted MRI data and normalized to standard space in order to use a standard anatomical atlas to help define the ROIs. Finally, as mentioned earlier, arterial samples are collected and we plan to use arterial input functions to correct for the complicated kinetics of the tracer. …”
Publicado 2018
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331463“…The trajectory of general self-efficacy followed almost the same pattern as hope: There were statistically significant increases in reported self-efficacy from baseline, with stabilization from 1 year to 6 years follow-up: F 3.37, p .002, η2 .14. Finally, resilience also increased significantly from baseline, with stabilization from 6 months to 6 years follow-up: F 5.12, p .000, η2 .21. …”
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331464por Nunez de Arco, Rossana Kathenca Peredo, Maziade, Michel, Jomphe, Valérie, Gilbert, Elsa, Paccalet, Thomas, Merette, Chantal“…Also, the performance gradually decreases from relatives of patients with psychosis to individuals at prodromal phase and finally to subjects at first episode of psychosis (Hou et al. 2016). …”
Publicado 2018
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331465por Rosen, Raymond, Trudeau, Jeremiah, Silverstein, Steven, Henderson, David, Smith, Adam, Walling, David, Garcia, Miguel, Davis, Bethany, Derogatis, Leonard, Sand, Michael“…Intraclass correlation coefficients were 0.78 for the overall 24-item PRECIS PRO and ranged from 0.49–0.74 for individual domains. Finally, discriminant validity testing confirmed there were significant differences between the patient group and the control group in each of the 5 domains of the revised 24-item PRECIS PRO (p<0.0001). …”
Publicado 2018
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331466“…We included 43 subjects in the final data analysis. Patients’ psychiatric disorders were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-R) by at least two experienced psychiatrists. …”
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331467por Bolhuis, Koen, Jansen, Philip R, Marroun, Hanan El, Hillegers, Manon H J, Tiemeier, Henning, Kushner, Steven A“…After genetic and neuroimaging quality control procedures, the final sample consisted of 522 participants. Linear regression models were conducted to examine the associations between schizophrenia polygenic risk scores, hair cortisol levels, and brain volumes. …”
Publicado 2018
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331468por Vingerhoets, Claudia, Tse, Desmond, van Oudenaren, Mathilde, van Duin, Esther, Hernaus, Dennis, Ramaekers, Jan, Janssen, Jaap, McAlonan, Grainne, Bloemen, Oswald, van Amelsvoort, Therese“…Furthermore, sustained attention was positively associated with ACC GABA levels (r= 0.700, p= 0.024) and negatively associated with GLU/GABA ratio r= -0.639, p= 0.047) in these patients. Finally, a positive correlation was found between visual memory and striatal GLU levels (r= 0.616, p= 0.043). …”
Publicado 2018
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331469por Howard, Robert, Cort, Elizabeth, Bradley, Rosie, Harper, Emma, Kelly, Linda, Bentham, Peter, Ritchie, Craig, Reeves, Suzanne, Fawzi, Waleed, Livingston, Gill, Sommerlad, Andrew, Oomman, Sabu, Nazir, Ejaz, Nilforooshan, Ramin, Barber, Robert, Fox, Chris, Macharouthu, Ajay Verma, Ramachandra, Pranathi, Pattan, Vivek, Sykes, John, Curran, Val, Katona, Cornelius, Dening, Tom, Knapp, Martin, Gray, Richard“…In stage 2, BPRS scores improved by a mean of 1·1 points (1·6) from 12 weeks to the final assessment in those who continued amisulpride but deteriorated by 5·2 points (2·0) in those who switched from amisulpride to placebo (difference 6·3 points [95% CI 0·9–11·7], p=0·024). …”
Publicado 2018
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331470por Guo, Yanting, Zheng, Gang, Fu, Tianyun, Hao, Shiying, Ye, Chengyin, Zheng, Le, Liu, Modi, Xia, Minjie, Jin, Bo, Zhu, Chunqing, Wang, Oliver, Wu, Qian, Culver, Devore S, Alfreds, Shaun T, Stearns, Frank, Kanov, Laura, Bhatia, Ajay, Sylvester, Karl G, Widen, Eric, McElhinney, Doff B, Ling, Xuefeng Bruce“…RESULTS: The development sample included 125,896 patients (72,572 women, 57.64%; mean 74.2 [SD 7.7] years). The final validation cohort included 153,199 patients (88,177 women, 57.56%; mean 74.3 [SD 7.8] years). …”
Publicado 2018
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331471por Shandiz, Mehdi Shirin, Rad, Hamid Saligheh, Ghafarian, Pardis, Yaghoubi, Khadijeh, Ay, Mohammad Reza“…As such, a bilinear (µ-map(CT-ref)), 5 (µ-map(CT-5c)), and 4 class µ-map (µ-map(CT-4c)) based on computed tomography (CT) images were generated. Finally, simulated PET data were corrected using µ-map(MR-5c) (PET-MRAC5c), µ-map(MR-4c) (PET-MRAC4c), µ-map(CT-5c) (PET-CTAC5c), and µ-map(CT-ref) (PET-CTAC). …”
Publicado 2018
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331472por Chen, Xin, Qian, Tianyi, Kober, Tobias, Zhang, Guojun, Ren, Zhiwei, Yu, Tao, Piao, Yueshan, Chen, Nan, Li, Kuncheng“…Visualization score analysis was used to evaluate the visualization of the five features on conventional, 3D-FLAIR, and FLAWS images. Finally, to explore the reason for false-positive results, a further evaluation of the whole brain FLAWS images was conducted for all the subjects. …”
Publicado 2018
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331473por Beheshti, Mohsen, Hehenwarter, Lukas, Paymani, Zeinab, Rendl, Gundula, Imamovic, Larisa, Rettenbacher, Rupert, Tsybrovskyy, Oleksiy, Langsteger, Werner, Pirich, Christian“…Therefore, data from 82 patients (76 undergoing surgery, 6 without surgery) in whom the standard of truth criteria were met, were used in the final analysis. RESULTS: All patients showed biochemical evidence of primary hyperparathyroidism with a mean serum calcium level of 2.78 ± 0.34 mmol/l and parathormone (PTH) level of 196.5 ± 236.4 pg/ml. …”
Publicado 2018
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331474por Ilievski, Vladimir, Zuchowska, Paulina K., Green, Stefan J., Toth, Peter T., Ragozzino, Michael E., Le, Khuong, Aljewari, Haider W., O’Brien-Simpson, Neil M., Reynolds, Eric C., Watanabe, Keiko“…Extracellular Aβ(42) was detected in the parenchyma in the experimental but not in the control group (p< 0.00001). Finally, phospho-Tau (Ser396) protein was detected and NFTs were evident in experimental but not in the control group (p<0.00001). …”
Publicado 2018
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331475por McConnell, Tracey, Best, Paul, Davidson, Gavin, McEneaney, Tom, Cantrell, Cherry, Tully, Mark“…Interestingly, service providers and service users were keen to become more involved in data analysis – this is one of the most under-researched and reported areas within the coproduction literature. Finally, we considered how user involvement worked within complex research designs and how this could be improved. …”
Publicado 2018
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331476por Guanais, Frederico, Doubova, Svetlana V., Leslie, Hannah H., Perez-Cuevas, Ricardo, García-Elorrio, Ezequiel, Kruk, Margaret E.“…Having a provider who knows relevant medical history was positively associated with better SRH in Mexico (aPR 1.47, 95% CI 1.03–2.12, p = 0.036) but was negatively associated with better SRH in Brazil (aPR 0.71, 95% CI 0.56–0.89, p = 0.003). Finally, easy contact with PC facility (Mexico: aPR 1.35, 95% CI 1.04–1.74, p = 0.023), coordination of care (Mexico: aPR 1.53, 95% CI 1.19–1.98, p = 0.001), and opportunity to ask questions (Brazil: aPR 1.42, 95% CI 1.11–1.83, p = 0.006) were each associated with better SRH. …”
Publicado 2018
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331477por Kahkoska, Anna R., Shay, Christina M., Crandell, Jamie, Dabelea, Dana, Imperatore, Giuseppina, Lawrence, Jean M., Liese, Angela D., Pihoker, Cate, Reboussin, Beth A., Agarwal, Shivani, Tooze, Janet A., Wagenknecht, Lynne E., Zhong, Victor W., Mayer-Davis, Elizabeth J.“…Multinomial models studied the association of race/ethnicity with HbA(1c) trajectory group membership, adjusting for demographic characteristics, clinical factors, and socioeconomic position. RESULTS: The final study sample of 1313 patients was 49.3% female (647 patients) with mean (SD) age 9.7 (4.3) years and mean (SD) disease duration of 9.2 (6.3) months at baseline. …”
Publicado 2018
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331478por Vannuccini, Silvia, Ferrata, Chiara, Perelli, Federica, Pinzauti, Serena, Severi, Filiberto M, Reis, Fernando M, Petraglia, Felice, Di Tommaso, Mariarosaria“…MAIN RESULTS AND THE ROLE OF CHANCE: The age of women in the final analysis ranged from 25 to 45 years, while BMI ranged from 17 to 34 kg/m(2). …”
Publicado 2018
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331479“…There were no significant differences between groups in final step count, fasting glucose levels, lipid levels, or total medication effect score at 12 months. …”
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331480por Ndiaye, Jean Louis A., Ndiaye, Youssoupha, Ba, Mamadou S., Faye, Babacar, Ndiaye, Maguette, Seck, Amadou, Tine, Roger, Thior, Pape Moussa, Atwal, Sharanjeet, Beshir, Khalid, Sutherland, Colin, Gaye, Oumar, Milligan, Paul“…The pfdhps-540E mutation associated with clinical resistance to sulfadoxine-pyrimethamine was found in 0.8% of samples from malaria cases but not in the final survey. Twelve children died in the control group and 14 in the SMC group, a rate difference of 0.096/1,000 child-months (95% CI 0.99, 1.18; p = 0.895). …”
Publicado 2019
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