“…After a quick overview of the Service Task, that has been performed during this work, in chapter 5, the used data sets and the choice of selected events are explained in chapter 6. Finally, the measurements of charged pions and photons are described in chapter 7 and 8, while the measurements of $\pi^{0}$ and $\eta$ meson production cross sections are described in chapter 9. …”
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“…This study was performed using a 1 m2 Micromegas, as long as no final assembled SM2 module exists. Dur- ing series production of the SM2 modules it is planned to calibrate all detectors with the CRF. …”
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“…The limitations will be the determination of the cost to meet said tax obligations that varies between companies and the sectors that comprise them, and the lack of programs and guidelines not yet established by the federal government for those that are not contemplated, to finally pour an opinion based in the evidence provided that reflects a sense in the economic life of Mexico.KEYWORDS: SMEs; Electronic accounting; Economic growth; Tax supervision. …”
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“…Multivariate analysis demonstrated that male gender（OR＝0.4, 95％ CI 0.2–0.9, P＝0.038 and OR＝0.3, 95％ CI 0.1–0.8, P＝0.015）, SWOG cytogenetic classification into unfavorable or intermediate（OR＝0.1, 95％ CI 0.1–0.6, P＝0.014 and OR＝0.1, 95％ CI 0.1–0.3, P＝0.004）and receiving low-intensity regimen as induction regimen（OR＝0.1, 95％ CI 0.1–0.3, P＝0.003 and OR＝0.1, 95％CI 0.1–0.2, P＝0.001）were typical adverse factors impacting the first CR and the final CR; PLT<45 × 10(9)/L（OR＝0.4, 95％CI 0.2–0.9, P＝0.038）and LDH ≥258 U/L（OR＝0.3, 95％CI 0.1–0.7, P＝0.005）were independent factors for CR. …”
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“…Among decedents, the percentages of participants who received an intensive procedure during the final month of life (estimated probability, 23.5% [95% CI, 16.5%-31.0%] comfort focused vs 26.1% [95% CI, 18.0%-34.5%] longevity focused or unsure; P = .64), discontinued dialysis (estimated probability, 38.3% [95% CI, 32.0%-44.8%] comfort focused vs 30.2% [95% CI, 23.0%-37.8%] longevity focused or unsure; P = .09), and enrolled in hospice (estimated probability, 32.2% [95% CI, 25.7%-38.7%] comfort focused vs 23.3% [95% CI, 16.4%-30.5%] longevity focused or unsure; P = .07) were not statistically different. …”
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“…The machine learning model with the best performance was screened out and compared with the TNM Classification using ROC, IBS, and C-index. Finally, patients were stratified based on the model with the best performance to assess whether they benefited from postoperative chemotherapy through the log-rank test. …”
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“…A total of 47 691 participants with available genotype data were recruited, and 37 317 participants aged 18 years or older were included in the final analysis after excluding participants who were lost to follow-up or with major chronic diseases, and those without blood lipid measurements at baseline and any follow-up survey. …”
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“…Of the 1593 patients in practices offering both video and telephone visits, 297 (16.7% weighted) were themselves offered telephone visits only; factors associated with being offered telephone only included Hispanic ethnicity (aOR, 1.96 [95% CI, 1.13-3.41]), limited English proficiency (aOR, 3.05 [95% CI, 1.28-7.31]), and less technology access (aOR, 1.68 [95% CI, 1.00-2.81] for those with low vs high access). Finally, of the 711 respondents who were themselves offered both video and telephone visits, 304 (43.1% weighted) had a telephone visit; factors associated with receiving telephone visits only were older age (aOR, 2.68 [95% CI, 1.21-5.92] for those aged 75-84 years vs 18-64 years) and less technology access (aOR, 2.65 [95% CI, 1.12-6.25] for those with moderate vs high access]). …”
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“…However, overall heterogenicity was high (I(2) = 95%). Finally, the use of ICPIs led to an improved side effect profile when compared with standard chemotherapy [RR 0.85 (95% CI 0.73–0.98)]. …”
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“…We also show that treatment of the liver HepG2 cells with the CCDC80 and SOD3 recombinant proteins impacts genes related to steatosis and lipid processing, including PPARA, NFE2L2, and RNF128. Finally, utilizing the adipose NAFLD DE gene cis-regulatory variants associated with serum triglycerides (TGs) in extensive genome-wide association studies (GWASs), we demonstrate a unidirectional effect of serum TGs on NAFLD with Mendelian Randomization (MR) analysis. …”
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“…The current protocol for the systematic review has been properly registered on PROSPERO (registration number: CRD42021241145). FINDINGS: The final analysis comprised 17 trials that involved 9128 patients and 19 distinct treatment regimens. …”
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“…To confirm the safety of HK013-G1, non-specific activation of 4-1BB signal mediated by Fc receptor and CRS was evaluated in vitro. Finally, we compared the antitumor activity of two bispecific antibodies in both MC38/hMSLN and CT26/hMSLN tumor model and hepatotoxicity as well as cardiotoxicity was evaluated. …”
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“…Multivariate linear regression models were used to estimate the association between shoulder morphology and strength. Finally, odds ratios (OR) were calculated using multivariate logistic regression models to estimate the likelihood of shoulder instability based on shoulder morphological outcomes. …”
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“…There were no significant differences in achieving MCID or PASS for HOS-ADL, HOS-SS, mHHS, or iHOT-12 at final follow-up. CA returned to sport (RTS) at a median of 25.2 weeks (Q1 22.4 – Q3 30.7) with an overall RTS rate of 90%. …”
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“…RESULTS: Among the 5 446 088 singleton births in the final analytic sample (maternal mean [SD] age, 28.8 [4.8] years), 310 384 were PTBs (maternal mean [SD] age, 29.5 [5.5] years). …”
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“…RESULTS: In calendar year 2004, a total of 13,420 patients were identified with a medical or hospital claim with ICD-9-CM code 340, a prevalence of approximately 14.0 per 10,000. The final study population was reduced to 10,099 patents (75.3%) after applying the criterion of 12 full months of available claims data. …”
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“…Several sensitivity analyses were conducted to verify all findings. RESULTS: The final analyses were conducted on 6,567 oxycodone CR patients and 796 oxymorphone ER patients. …”
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“…Of the 361 (69.6%) patients included in the final analysis, the mean (SD) age was 50.0 (8.9); the majority was Chinese (80.1%) and diagnosed with stage 2 or higher breast cancer (88.1%). …”
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“…Eligibility criteria for prospective enrollment were (a) 1 or more risk factors: at least 1 chronic disease or an event (e.g., emergency room visit, adverse drug reaction, medication nonadherence) or aged 50 years or older, (b) a scheduled visit to see a PCP within 2 weeks from the screening date or a diagnosis of diabetes without a PCP visit during the first 6 months of the study, (c) need for optimization of medication therapy as determined by a clinical pharmacist on the screening date, and (d) 12 months of continuous insurance eligibility before enrollment in the study. For inclusion in the final study analyses, patients were also required to have continuous insurance eligibility through 12 months from study enrollment. …”
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“…Descriptive analyses were conducted to compare generic dispensing ratios between (1) all mail-order and community pharmacy claims, and (2) a market basket of therapeutic categories most commonly found within the mail-order channel. Finally, the difference in price per unit was calculated between mail-order and community pharmacy channels for the top 20 generic drug products. …”
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