“…We further assessed the impact of using cystatin-C-based eGFR in risk prediction equations for CKD progression and all-cause mortality and investigated non-GFR determinants of eGFR(cys). Finally, we estimated the cost implications of implementing National Institute for Health and Care Excellence (NICE) guidance to use eGFR(cys) to confirm the diagnosis in people classified as CKD G3aA1 by eGFR(creat). …”
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“…Three groups of children could not be included in the final analysis: 147 migrated out of the study area (67 in intervention clusters; 80 in control clusters), 77 died after the neonatal period and before 18 months (31 in intervention clusters; 46 in control clusters), and seven had implausible length-for-age Z scores (<–5 SD; one in intervention cluster; six in control clusters). …”
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“…Serum VRC01 levels were detected through 12 weeks after final administration in all participants who received all scheduled doses. …”
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“…New Hybrids analysis found that individuals from all five Merced habitat-associated populations and the population from Oroville were primarily categorized as hybrids backcrossed to the Cx. pipiens population. Finally, all five habitat-associated populations shared more alleles with Cx. pipiens than with Cx. quinquefasciatus, even though the pure Cx. quinquefasciatus population was more geographically proximate to Merced. …”
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“…We developed an integrated blood and brain endophenotype score that summarized the relative importance of each metabolite to severity of AD pathology and disease progression (Endophenotype Association Score in Early Alzheimer’s Disease [EASE-AD]). Finally, we mapped the main metabolite classes emerging from our analyses to key biological pathways implicated in AD pathogenesis. …”
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“…Hazard ratios (HR) were estimated using Cox Proportional Hazards models with age as time scale, and adjusting for sex, calendar time and other psychiatric comorbidity. Finally, we estimated the absolute risk of being diagnosed with other mental disorders after being diagnosed with a specific disorder. …”
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“…M(k)(G, F(R)) includes the elements of the fragment of interest and those that are connected with it, through paths of length k. Finally, total (and local) quadratic indices have been used in QSPR studies of four series of organic compounds. …”
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“…Secondly, a hierarchical smoothing strategy is proposed to enhance the OF by using the two-orientation-zone filtering and the three-orientation-zone filtering, aiming to correct the spurious ridges and preserving the genuine location of singular points. Finally, three experiments are designed to test the proposed algorithm together with other popular gradient based methods on real fingerprint images, which are selected from different categories and all are suffering from obvious noise effects. …”
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“…Second, this is a 2-year follow-up study and the results may change in the longer-term. Finally, we relied on self-reported questionnaire data and there is a possibility that some women were unknowingly pregnant at T1 but this risk should be distributed equally in the three groups through randomization. …”
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“…MAIN RESULTS AND THE ROLE OF CHANCE: The final analysis included 194 women: 95 women with MRKH syndrome with a mean age of 40.9 years and 99 control women with a mean age of 30.2 years. …”
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“…Under the threshold of the top 1%, 239 regions were finally identified as candidate selected regions and 162 candidate genes were found based on the UMD3.1 genome assembly. …”
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“…Of those, 46 studies were utilized in the final synthesis of the systematic review. The most relevant findings were (a) the identification of an independent replication of the association between AQP1 gene sequence variant rs1049305 (C > G) and CE performance; (b) the association of the rs1049305 C-allele with faster CE running performance; (c) in knockout model, using a linear regression analysis of distance run as a function of Aqp1 status (Aqp1-null vs. wild-type mice) and conditions of hypoxia (ambient [O(2)] = 16%), normoxia (21%), and hyperoxia (40%) indicated that the Aqp1 knockout ran less distance than the wild-type mice (p < 0.001); (d) in vitro, a reduced AQP1 expression was associated with the presence of the rs1049305 G-allele; (e) AQP1 null humans led normal lives and were entirely unaware of any physical limitations. …”
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“…When oxidized fish oil was added, aged maize reduced serum antioxidant capacity further, inhibited the expressions of genes related to intestinal nutrient transport, promoted intestinal inflammation, and also reduced the apparent total tract digestibility (ATTD) of nutrients, increased diarrhea and finally reduced the growth performance of piglets. …”
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“…The results demonstrated that birds fed RI11 diets had significantly higher final body weight, total weight gain and average daily gain than the birds that received the NC, PC and AA treatments. …”
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“…RESULTS/ANTICIPATED RESULTS: There were 39 patients in the final cohort; thirteen of whom who participated in the pilot project, POET (Perioperative Educational Tool). …”
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“…Participants were then asked to consider what they wished they knew more about in relation to research knowledge, skills or behaviors. Participants were finally asked to discuss the resources or support they thought would help them to manage the challenges or meet the learning needs they identified. …”
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“…We anticipate that our final GDM data set will include 2000–3000 individuals. …”
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“…The results of this meta-analysis, accordingly, can inform practical training designs. Finally, guidelines and recommendations for conducting future research, using global positioning system devices, are suggested. …”
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“…Moreover, men’s testosterone had a positive correlation with IR in T1D. Finally, patients with T1D and a positive family history of T2D were not susceptible to weight gain, while MS metabolic phenotype prevalence tended to be higher in obese than in lean patients with T1D, with a tendency to significant difference.…”
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“…This suggests that, other factors being equal, the base case substitution elasticities provide the largest possible ILUC emissions value for soy biodiesel. Finally, our analyses clearly indicate that those analyses that limit their modeling framework to only palm and soy oil and ignore other types of vegetable oils and fats provide misleading information and exaggerate about the land use implications of the US biofuels for M&I. …”
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