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332341por Merner, Bronwen, Schonfeld, Lina, Virgona, Ariane, Lowe, Dianne, Walsh, Louisa, Wardrope, Cheryl, Graham-Wisener, Lisa, Xafis, Vicki, Colombo, Cinzia, Refahi, Nora, Bryden, Paul, Chmielewski, Renee, Martin, Fiona, Messino, Nancy M, Mussared, Anne, Smith, Lorraine, Biggar, Susan, Gill, Marie, Menzies, David, Gaulden, Carolyn M, Earnshaw, Leia, Arnott, Leslie, Poole, Naomi, Ryan, Rebecca E, Hill, Sophie“…From this group, we selected 33 studies to include in the final synthesis. These studies came from a wide range of countries including 28 from high‐income countries and five from low‐ or middle‐income countries (LMICs). …”
Publicado 2023
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332342por Brinkman, Joseph, McQuivey, Kade, Makovicka, Justin, Tummala, Sailesh, Economopoulos, Kostas“…Later, HA+LET was performed due to emerging studies showing higher failure rates in high risk patients undergoing HA alone compared to those undergoing HA+LET. Finally, the senior author transitioned to using QA for most cases. …”
Publicado 2023
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332343por Wright, Christian, Lee, Marissa, Gatti, Anthony, Veerkamp, Matthew, Chaudhari, Akshay, Delp, Scott, Parikh, Shital, Pace, James, Shea, Kevin, Sherman, Seth“…We then calculated Pearson correlations between these identified knee position PCs and each clinical measure, with |r| < 0.3 poor, 0.3 - 0.6 fair, 0.6 - 0.8 moderately strong, and > 0.8 very strong. RESULTS: Our final analysis included MRIs from 110 patients after removing 38 patients with automatic segmentation errors. …”
Publicado 2023
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332344por Romualdi, D, Ata, B, Bhattacharya, S, Bosch, E, Costello, M, Gersak, K, Homburg, R, Mincheva, M, Norman, R J, Piltonen, T, Dos Santos-Ribeiro, S, Scicluna, D, Somers, S, Sunkara, S K, Verhoeve, H R, Le Clef, N“…Following stakeholder review of an initial draft, the final version was approved by the GDG and the ESHRE Executive Committee. …”
Publicado 2023
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332345por Frias, Juan Pablo, Auchus, Richard Joseph, Bancos, Irina, Blonde, Lawrence, Busch, Robert S, Buse, John B, DeFronzo, Ralph Anthony, Findling, James W, Fonseca, Vivian, Hamidi, Oksana, Handelsman, Yehuda, Pratley, Richard E, Rosenstock, Julio, Tudor, Iulia Cristina, Moraitis, Andreas G, Einhorn, Daniel“…DeFronzo: None. J.W. Findling: Advisory Board Member; Self; Corcept Therapeutics. …”
Publicado 2023
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332346“…These feature sets and outcome measures were then fed into mikropml, and 25 separate train/test splits of the data were performed, each with 100-fold cross-validation, to come to final predictive models for severity outcome. Feature Counts for the different Feature Sets and Phenotype Splits [Figure: see text] The features included for each analysis was dependent on 1) the strains present in the phenotype split and 2) the filtering method for the feature set. …”
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332347por Tan, Linda C, Mowat, Alastair G, Fazou , Chrysoula, Rostron , Tim, Roskell, Helen, Dunbar , P Rod, Tournay, Claire, Romagné, François, Peyrat, Marie-Alix, Houssaint, Elisabeth, Bonneville, Marc, Rickinson, Alan B, McMichael , Andrew J, Callan, Margaret FC“…Alternatively, T cells specific for certain viral epitopes may be stimulated to proliferate within the joint, by viral antigens themselves or by cross-reactive self-antigens. Finally, it is theoretically possible that subpopulations of T cells within the joint are preferentially protected from apoptotic cell death. …”
Publicado 2000
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332348“…No reaction was obtained in any of the animals. Finally, the transmission of herpes zoster to monkeys was attempted. …”
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332349“…STUDY ELIGIBILITY CRITERIA: The initial search identified 506 studies, with a final yield of 25 studies. Only RCTs that examined the effects of RT in adults with a mean age of 65 and older were included. …”
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332350Publicado 2016“…Second, we examined factors affecting total mortality patterns through a series of counterfactual scenarios, testing the magnitude by which population growth, population age structures, and epidemiological changes contributed to shifts in mortality. Finally, we attributed changes in life expectancy to changes in cause of death. …”
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332351por Mistry, Hema, Nduka, Chidozie, Connock, Martin, Colquitt, Jill, Mantopoulos, Theodoros, Loveman, Emma, Walewska, Renata, Mason, James“…The company submitted further evidence, and the final guidance recommended venetoclax for use with the Cancer Drugs Fund for the two populations in this technology appraisal. …”
Publicado 2017
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332352“…No statistical analysis for evaluating the association between the severity of the disease outcome and smoking status was conducted in that study. Finally, Liu et al.(13) found among their population of 78 patients with COVID-19 that the adverse outcome group had a significantly higher proportion of patients with a history of smoking (27.3%) than the group that showed improvement or stabilization (3.0%), with this difference statistically significant at the p=0.018 level. …”
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332353“…INTERVENTION AND COMPARATOR: The study consists of a Screening Period of up to 3 days, a Primary Evaluation Period of 4 weeks, a final assessment at Day 29, and a Follow-up Period of 8 weeks. …”
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332354“…The primary objective of the study, however, was to investigate the buffering effect of two psychological resources—meaningfulness and self-control—with regard to the relation between acute COVID-19 stress and general mental distress. Finally, a potential aggravation of mental distress due to the occurrence of crises of meaning was examined. …”
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332355por van Eekelen, R, Eijkemans, M J, Mochtar, M, Mol, F, Mol, B W, Groen, H, van Wely, M“…PARTICIPANTS/MATERIALS, SETTING, METHODS: The main outcomes per policy over the 3-year period were the probability of live birth, the average treatment and delivery costs, the probability of multiple pregnancy, the incremental cost-effectiveness ratio (ICER) and finally, which policy yields the highest net benefit in which costs for a policy were deducted from the health effects, i.e. live births gained. …”
Publicado 2020
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332356“…There was also a 3.8cm infrarenal inflammatory abdominal aortic pseudoaneurysm (Fig 3), and finally a 2.3cm right lower lobe pulmonary artery aneurysm. …”
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332357“…NIV was avoided as it required a full-face mask to minimize particle dispersion but would pose an asphyxiation risk as patient was coughing up blood. Finally, the team learnt to be flexible in these extraordinary circumstances when dealing with the end-of-life decisions of the COVID-19 positive patient. …”
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332358por Ray, Arghya, DU, Ting, Chauhan, Krishan, Song, Yan, Chauhan, Dharminder, Anderson, Kenneth“…Taken together, we show that TBK1 is downregulated in pDCs, and pDCs-MM interactions further decreases TBK1 in MM, thereby attenuating IFN-mediated anti-viral immune response signaling in MM. Finally, we found that blockade of proteasome-mediated protein degradation via inhibition of Ubiquitin receptor Rpn13 upregulates TBK-1 expression, indicating potential clinical use of targeting Rpn13 in restoring anti-viral immune responses in MM. …”
Publicado 2020
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332359por Kastritis, Efstathios, Terpos, Evangelos, Sklirou, Aimilia D., Theodorakakou, Foteini, Fotiou, Despina, Papanagnou, Eleni-Dimitra, Bagratuni, Tina, Kanellias, Nikolaos, Migkou, Magdalini, Ntanasis-Stathopoulos, Ioannis, Malandrakis, Panagiotis, Charitaki, Ioanna, Gavriatopoulou, Maria, Trougakos, Ioannis P., Dimopoulos, Meletios-Athanasios“…The study included 144 patients with AL amyloidosis, of which 120 had NAbs titers assessed on all time points and were included in the final analysis (53% males; median age: 66, IQR: 57-72 years) and 240 matched controls (53% males; median age: 66, IQR: 57-72 years). 66 (55%) AL patients were on active therapy, 17.5% were on daratumumab (DARA)-based therapy, 52 (43%) had discontinued therapy >3 months from the date of the first shot, 19% had prior exposure to DARA and 94 (78%) were in hematologic remission (CR or VGPR). …”
Publicado 2021
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332360por Choi, Yun, Caro, Jessica, Li, Xiaochun, Al-Obeidi, Arshed, Kurtz, Sharyn Lynn, Kim, Austin I., Chang, Julie E., Olszewski, Adam J., Zayac, Adam, Matthews, Andrew, Barta, Stefan K., Sundaram, Suchitra, Hernandez-Ilizaliturri, Francisco J., Leslie, Lori A., Caimi, Paolo, Carter, Jordan, David, Kevin A., Evens, Andrew M., Kim, Myung Sun, Nagle, Sarah J., Goldberg, Judith, Diefenbach, Catherine S.“…While center effects were statistically significant, center by covariate interaction effects were not and are not included in the final models. The odds ratio (OR) estimates and p-values for each patient and CLL/lymphoma clinical variable are shown in Tables 3 and 4, respectively. …”
Publicado 2021
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