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301por Deka, Ranjit K., Brautigam, Chad A., Liu, Wei Z., Tomchick, Diana R., Norgard, Michael V.“…We recently reported a flavin‐trafficking protein (Ftp) in the syphilis spirochete Treponema pallidum (Ftp_Tp) as the first bacterial metal‐dependent FAD pyrophosphatase that hydrolyzes FAD into AMP and FMN in the periplasm. …”
Publicado 2015
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302por Wang, Jing, Long, Cheng, Zhang, Haijun, Zhang, Yanan, Wang, Hao, Yue, Hongyuan, Wang, Xiaocui, Wu, Shugeng, Qi, Guanghai“…Genetic variant T329S in flavin-containing monooxygenase 3 (FMO3) impairs trimethylamine (TMA) metabolism in birds. …”
Publicado 2016
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303“…In this study, we demonstrate that a new flavin probe, composed of palmitoylated peptide nucleic acid (PNA) and its complementary PNA labeled with flavin, targets the liquid-ordered (lo) microdomains and disrupts its interfaces to liquid-disordered (ld) microdomains of giant unilamellar vesicles and can be visualized by using confocal laser scanning microscopy. …”
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304por Lyu, Syue-Yi, Lin, Kuan-Hung, Yeh, Hsien-Wei, Li, Yi-Shan, Huang, Chun-Man, Wang, Yung-Lin, Shih, Hao-Wei, Hsu, Ning-Shian, Wu, Chang-Jer, Li, Tsung-Lin“…When benzoylformate (the product of the first two-electron oxidation) and hydrogen peroxide (an oxidant) were used as substrates the reaction did not proceed, suggesting that free hydrogen peroxide is not the committed oxidant in the second two-electron oxidation. How the flavin mononucleotide (FMN)-dependent four-electron oxidation reaction takes place remains elusive. …”
Publicado 2019
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305por Fisher, Brian F., Snodgrass, Harrison M., Jones, Krysten A., Andorfer, Mary C., Lewis, Jared C.“…In this study, family-wide activity profiling was used to obtain sequence–function information on flavin-dependent halogenases (FDHs). This broad survey provided a number of insights into FDH activity, including halide specificity and substrate preference, that were not apparent from the more focused studies reported to date. …”
Publicado 2019
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306por Wang, Deng, Wang, Ying, Yang, Jing, He, Xiu, Wang, Rui-Jie, Lu, Zhi-Song, Qiao, Yan“…The flavin-based indirect electron transfer process between electroactive bacteria and solid electrode is crucial for microbial fuel cells (MFCs). …”
Publicado 2020
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307por Hammers, D. Scott, Donaghy, Caroline M., Heiss, Sarah L., Harris, Lydia M., Gordon, Jackson M., Stevens, John W., Murray, Lucian P., Schwab, Alexander D., Hester, Brooke C., Culpepper, Megen A.“…This enzyme requires a flavin reductase B subunit to supply electrons to the monooxygenase A subunit where DMS conversion occurs. …”
Publicado 2020
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308por Arib, Celia, Liu, Hui, Liu, Qiqian, Cieutat, Anne-Marie, Paleni, Didier, Li, Xiaowu, Spadavecchia, Jolanda“…Flavin adenine dinucleotide (FAD) is engaged in several metabolic diseases. …”
Publicado 2021
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309“…Notably the neutral un-metalated flavin analogue did not show any significant catalytic activity. …”
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310por Song, Jianlou, Shi, Xuefeng, Li, Xianyu, Liang, Qianni, Zeng, Lingsen, Li, Guangqi, Yan, Yiyuan, Xu, Guiyun, Zheng, Jiangxia“…This study aimed to evaluate the effects of the spontaneous genetic mutation T329S in flavin-containing monooxygenase 3 (FMO3) on atherosclerosis (AS), fatty liver syndrome (FLS), and adiposity in 90-week-old layers. …”
Publicado 2022
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311por Massey, William, Osborn, Lucas J., Banerjee, Rakhee, Horak, Anthony, Fung, Kevin K., Orabi, Danny, Chan, E. Ricky, Sangwan, Naseer, Wang, Zeneng, Brown, J. Mark“…Here, we show that TCDD exposure in mice profoundly stimulates the hepatic expression of flavin-containing monooxygenase 3 (Fmo3), which is a hepatic xenobiotic metabolizing enzyme that is also responsible for the production of the gut microbiome-associated metabolite trimethylamine N-oxide (TMAO). …”
Publicado 2022
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312“…Two kinds of peptide nanotubes are prepared from cyclo(β-Asp(flavin)-β-alanine-β-alanine) (C3FAA) and cyclo(β-Asp(flavin)-ethylenediamine-succinic acid) (C3FES). …”
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313por Luo, Tiantian, Guo, Zhigang, Liu, Dan, Guo, Zhongzhou, Wu, Qiao, Li, Qinxian, Lin, Rongzhan, Chen, Peier, Ou, Caiwen, Chen, Minsheng“…Unexpectedly, hepatic RNA-seq indicated upregulated flavin monooxygenase 3 (FMO3) expression following PSRC1 knockout. …”
Publicado 2022
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314“…Here we use a variety of spin dynamics simulation methods to estimate the hyperfine-only values of B(1/2) for the flavin-tryptophan radical pair, [FAD˙(−) TrpH˙(+)], thought to be the detector in the magnetic compass sense of migratory songbirds. …”
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315por Oka, Yoshimi“…Here, anchor-matched PNA was demonstrated to be excluded from the lo microdomains of giant unilamellar vesicles by hybridization with the complementary flavin-labeled DNA. As shown in control experiments using Alexa Fluor 488-labeled DNA, which showed that the preferential partitioning was the lo domain, the domain distribution of PNA was not only dependent on the lipophilic anchor but also on the structure of the hybridized DNA or PNA pair. …”
Publicado 2022
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316por Xiong, Qing, Fung, Cathy Sin-Hang, Xiao, Xiaojun, Wan, Angel Tsz-Yau, Wang, Mingqiang, Klimov, Pavel, Ren, Yaning, Yang, Kevin Yi, Hubert, Jan, Cui, Yubao, Liu, Xiaoyu, Tsui, Stephen Kwok-WingEnlace del recurso
Publicado 2023
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317por Kim, Ju Yeong, Yi, Myung-hee, Kim, Myungjun, Choi, Jun Ho, Lee, Seogwon, Yong, Tai-Soon“…METHODS: D. farinae was cultivated in the presence of ampicillin powder in an autoclaved medium for 6 weeks. …”
Publicado 2023
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318“…House dust mites (HDMs) are a major source of indoor allergens that cause airway allergic disease. Dermatophagoides farinae, a predominant species of HDMs in China, has demonstrated pathogenic role in allergic disorders. …”
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319“…This paper reviews recent human studies on the bioavailability of chlorogenic acids in coffee and green tea flavan-3-ols in which the identification of metabolites, catabolites and parent compounds in plasma, urine and ileal fluid was based on mass spectrometric methodology. …”
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320“…Silica gel column chromatographic separation of the methanol extract afforded 3,5,7,3′,4′-pentahydroxyflavan, named epicatechin (1), along with a close flavan derivative (2). Structures of the compounds were elucidated by spectroscopic techniques (1D and 2D NMR, FTIR, and UV-Vis). …”
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