Mostrando 681 - 700 Resultados de 20,270 Para Buscar 'Flavina~', tiempo de consulta: 2.93s Limitar resultados
  1. 681
  2. 682
  3. 683
    “…Here, we show that commonly available flavones are effective inhibitors of DYRK1A. The observed biochemical activity of flavone compounds is confirmed by crystal structures solved at 2.06 Å and 2.32 Å resolution, deciphering the way inhibitors bind in the ATP-binding pocket of the kinase, which is driven by the arrangement of hydroxyl moieties. …”
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  4. 684
    “…Flavone acetic acid (FAA) is a synthetic flavonoid with dramatic pre-clinical anti-tumour activity involving a vascular component in its mechanism but no clinical effects have been seen to date. …”
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  5. 685
    “…The antitumour activity of flavone acetic acid (FAA) was evaluated against two human colorectal carcinoma (HCC) lines, HCC-P2988 and HCC-M1410, transplanted into nude mice. …”
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  6. 686
    “…This study has indicated that the tumour is resistant to a large number of standard anti-cancer drugs but is highly responsive to the investigational agent flavone acetic acid (FAA). The levels of FAA achieved in tumours are lower than those necessary for activity in vitro suggesting its mechanism of action in vivo is not direct cytotoxicity. …”
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  7. 687
    “…In this study, a simple method for preparative separation of the two flavone glucuronides was established with macroporous resins. …”
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  8. 688
    “…O-methyltransferase (TaOMT2) catalyzes the sequential methylation of the flavone, tricetin, to its 3'-methyl- (selgin), 3',5'-dimethyl- (tricin) and 3',4',5'-trimethyl ether derivatives. …”
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  9. 689
  10. 690
    “…The natural flavone acacetin has been demonstrated to inhibit transient outward potassium current (I(to)) in human atrial myocytes. …”
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  11. 691
    “…In this work, we report two new flavone-based fluorescent probes, MC-Mito1 and MC-Mito2, for monitoring mitochondria in living cells. …”
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  12. 692
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  20. 700
    “…The twigs of Morus alba L. were found to show strong tyrosinase inhibition activity, and the responsible active components in the extract were further investigated in this study. A flavone, named morusone (1), and sixteen known compounds 2–17 were isolated from M. alba twigs and their structures were identified by interpretation of the corresponding ESI-MS and NMR spectral data. …”
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