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841por El Shoubaky, Gihan A., Abdel-Daim, Mohamed M., Mansour, Mohamed H., Salem, Essam A.“…Physicochemical investigation of the red alga Acanthophora spicifera (Vahl) Borgesen, collected from Al-Shoaiba coast, Red Sea, Saudi Arabia, led to the isolation of a flavone from the algal tissue with acetone. Preparative chromatography on silica gel thin-layer chromatography was used for the separation of the flavone and eluted with the methanol:chloroform:ethyl acetate (1:7:2) solvent system. …”
Publicado 2016
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842por Mizuno, Hiroshi, Yazawa, Takayuki, Kasuga, Shigemitsu, Sawada, Yuji, Kanamori, Hiroyuki, Ogo, Yuko, Hirai, Masami Yokota, Matsumoto, Takashi, Kawahigashi, Hiroyuki“…These results suggest that expression of FNSII is related to the synthesis of flavones (apigenin and luteolin) and the expression level of F3′H is related to the balance of apigenin and luteolin. …”
Publicado 2016
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843por Du, Hongxu, Yang, Jingjing, Bai, Jingying, Ming, Ke, Shi, Jintong, Yao, Fangke, Zhang, Wei, Yu, Yang, Chen, Yun, Xiong, Wen, Wu, Yi, Wang, Deyun, Hu, Yuanliang, Liu, Jiaguo“…The results showed that the hepatic redox status was significantly disturbed so that causing the mitochondrial dysfunction, ATP depletion and mitochondrial oxidative stress during the process of the DHAV-1 infection, and a prescription formulated with Hypericum japonicum flavone, Radix Rehmanniae Recens polysaccharide and Salvia plebeia flavone (HRS), which had been demonstrated with good anti-oxidative activity in serum, could effectively alleviate the hepatic injury and the oxidative stress in liver tissue induced by DHAV-1 thus alleviating the mitochondrial injury and oxidative stress. …”
Publicado 2017
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844por Zhu, Yi, Doornebal, Ewald J., Pirtskhalava, Tamar, Giorgadze, Nino, Wentworth, Mark, Fuhrmann-Stroissnigg, Heike, Niedernhofer, Laura J., Robbins, Paul D., Tchkonia, Tamara, Kirkland, James L.“…Here we report that fisetin, a naturally-occurring flavone with low toxicity, and A1331852 and A1155463, selective BCL-X(L) inhibitors that may have less hematological toxicity than the less specific BCL-2 family inhibitor navitoclax, are senolytic. …”
Publicado 2017
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846por Zhao, Qing, Cui, Meng-Ying, Levsh, Olesya, Yang, Dongfeng, Liu, Jie, Li, Jie, Hill, Lionel, Yang, Lei, Hu, Yonghong, Weng, Jing-Ke, Chen, Xiao-Ya, Martin, Cathie“…Here, we report the isolation and characterization of two CYP450 enzymes, SbCYP82D1.1 and SbCYP82D2, which function as the flavone 6-hydroxylase (F6H) and flavone 8-hydroxylase (F8H), respectively, in S. baicalensis. …”
Publicado 2018
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847por Wu, Xiaowei, Yu, Na, Zhang, Yuping, Ye, Yuanning, Sun, Wenrong, Ye, Lei, Wu, Huimin, Yang, Zhao, Wu, Lin, Wang, Fangyu“…BACKGROUND: Radix Tetrastigma hemsleyani flavone (RTHF) is extracted from a traditional Chinese medicinal herb T. hemsleyani, which is conventionally used as a folk medicine for its anti-inflammation activity and antiviral activity. …”
Publicado 2018
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848“…BACKGROUND: Radix Tetrastigma Hemsleyani Flavone (RTHF) has detoxification and anti-inflammation activity and is widely used. …”
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849“…Flavones are known as an inhibitor of tankyrase, a potential drug target of cancer. …”
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850“…BACKGROUND: Flavone C-glycosides are difficult to be deglycosylated using traditional chemical methods due to their solid carbon–carbon bond between sugar moieties and aglycones; however, some bacteria may easily cleave this bond because they generate various specific enzymes. …”
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851“…Phytochemical analysis suggested that this plant contained some flavones. O. indicum fruit and seed water and ethanol extracts and their major flavonoids including baicalein, baicalin, and chrysin were tested for in vitro antibacterial activities on four clinical isolated bacteria, namely, Staphylococcus intermedius, Streptococcus suis, Pseudomonas aeruginosa, and β-Escherichia coli, using a broth micro-dilution assay. …”
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852por Oliveira, Ana P., Silva, Andressa L.N., Viana, Lucas G.F.C., Silva, Mariana G., Lavor, Érica M., Oliveira-Júnior, Raimundo G., Alencar-Filho, Edilson B., Lima, Ricardo S., Mendes, Rosemairy L., Rolim, Larissa A., Anjos, Débora S.C., Ferraz, Leslie R.M., Rolim-Neto, Pedro J., Silva, Maria F.S., Pessoa, Claudia do Ó., Almeida, Jackson R.G.S.“…Cirsiliol is a flavone found in many Lamiaceae species with high cytotoxic activity against tumor cell lines. …”
Publicado 2019
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853“…However, flavone synthase (FNS), the key enzyme for flavone biosynthesis, has not yet been characterized in mulberry. …”
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854por Yue, Grace Gar-Lee, Gao, Si, Lee, Julia Kin-Ming, Chan, Yuk-Yu, Wong, Eric Chun-Wai, Zheng, Tao, Li, Xiao-Xiao, Shaw, Pang-Chui, Simmonds, Monique S. J., Lau, Clara Bik-San“…Tricin, a flavone isolated from rice bran, has been shown to be chemopreventive in a colorectal cancer (CRC) mouse model. …”
Publicado 2020
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855por Ibrahim, Mahmoud A.A., Mohamed, Eslam A.R., Abdelrahman, Alaa H.M., Allemailem, Khaled S., Moustafa, Mahmoud F., Shawky, Ahmed M., Mahzari, Ali, Hakami, Abdulrahim Refdan, Abdeljawaad, Khlood A.A., Atia, Mohamed A.M.“…According to the results, 371 flavone analogs exhibited good potency towards M(pro) with docking scores less than −9.0 kcal/mol. …”
Publicado 2021
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856por Wang, Rong, Chen, Tuo, Wang, Qiong, Yuan, Xiao-Min, Duan, Zheng-Lan, Feng, Ze-Yu, Ding, Yang, Bu, Fan, Shi, Guo-Ping, Chen, Yu-Gen“…PURPOSE: Total flavone of Abelmoschus manihot (TFA), the effective constituents extracted from Flos Abelmoschus Manihot, has been reported to inhibit inflammation. …”
Publicado 2021
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857por Zhou, Li-Jie, Geng, Zhiqiang, Wang, Yuxi, Wang, Yiguang, Liu, Shenhui, Chen, Chuwen, Song, Aiping, Jiang, Jiafu, Chen, Sumei, Chen, Fadi“…Flavones are among the major colorless pigments synthesized through branches of the flavonoid pathway in plants. …”
Publicado 2021
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859por Bouchal, Johannes M., Güner, Tuncay H., Velitzelos, Dimitrios, Velitzelos, Evangelos, Denk, Thomas“…We investigated leaves and dispersed spores/pollen from 6.4 to 6 Ma strata in the intermontane Florina–Ptolemais–Servia Basin (FPS) of northwestern Greece. …”
Publicado 2020
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