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61por Arrieta, Antonio C., Sung, Lillian, Bradley, John S., Zwaan, C. Michel, Gates, Davis, Waskin, Hetty, Carmelitano, Patricia, Groll, Andreas H., Lehrnbecher, Thomas, Mangin, Eric, Joshi, Amita, Kartsonis, Nicholas A., Walsh, Thomas J., Paschke, Amanda“…The percentage of subjects that achieved the C(avg) target of 500 to 2500 ng/mL on Day 7 ranged from 31% to 80%, with the lowest proportion in subjects 2 to <7 years receiving 12 mg/kg/day BID (AG2/DC1) and the highest proportion in subjects 7 to <18 years receiving 18 mg/kg/day TID (AG1/DC3). At all three dose levels (12 mg/kg/day BID, 18 mg/kg/day BID and 18 mg/kg/day TID), subjects in AG1 (7 to <18 years old) had higher mean PK exposures at steady state than those in AG2. …”
Publicado 2019
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63por Napolitano, Antonella, Miller, Sam, Murgatroyd, Peter R., Hussey, Elizabeth, Dobbins, Robert L., Bullmore, Edward T., Nunez, Derek J.R.“…We therefore conducted a pilot study comparing the effects on body composition of two SGLT2 inhibitors, remogliflozin etabonate (RE) 250 mg TID (n = 9) and sergliflozin etabonate (SE) (1000 mg TID) (n = 9), with placebo (n = 12) in obese non-diabetic subjects. …”
Publicado 2013
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64por Chiwaridzo, M., Munambah, N., Oorschot, S., Magume, D., Dambi, J. M., Ferguson, G., Smits-Engelsman, B. C. M.“…Given the increased participation rates, burgeoning talent identification (TID) programs and the reportedly high injury-risk associated with competitive youth rugby, the minimal qualities or skills needed for effective performance by all young players need further clarification. …”
Publicado 2019
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65por Smith, Steve R., Aronne, Louis J., Burns, Colleen M., Kesty, Nicole C., Halseth, Amy E., Weyer, Christian“…By month 12, initial 4-month weight loss was regained in the placebo group but was maintained in all but the 120-μg b.i.d. group. Placebo-corrected weight loss with 120 μg t.i.d. and 360 μg b.i.d. averaged 3.2 ± 1.2 kg (3.1 ± 1.1% body wt) and 3.3 ± 1.1 kg (3.1 ± 1.0% body wt), respectively, at month 4 (both P < 0.01; 4-month evaluable n = 270) and 6.1 ± 2.1 kg (5.6 ± 2.1% body wt) and 7.2 ± 2.3 kg (6.8 ± 2.3% body wt), respectively, at month 12 (both P < 0.01; 12-month evaluable n = 146). …”
Publicado 2008
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66por Verschuur, Constant V. M., Suwijn, S. R., Post, B., Dijkgraaf, M., Bloem, B. R., van Hilten, J. J., van Laar, T., Tissingh, G., Deuschl, G., Lang, A. E., de Haan, R. J., de Bie, R. M. A.“…Subsequently, all patients receive levodopa/carbidopa 100/25 mg TID for 40 weeks. …”
Publicado 2015
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67por Asser, Andres, Hikima, Atsuko, Raki, Mari, Bergström, Kim, Rose, Sarah, Juurmaa, Julius, Krispin, Villem, Muldmaa, Mari, Lilles, Stella, Rätsep, Hanna, Jenner, Peter, Kõks, Sulev, Männistö, Pekka T., Taba, Pille“…To determine how toxicity occurs, we have investigated the effects of 4-week intraperitoneal administration of Mn (30 mg/kg t.i.d) and Mcat (100 mg/kg t.i.d.) given alone, on the nigrostriatal function in male C57BL6 mice. …”
Publicado 2019
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68por Nikolaou, Kalliopi N., Gournellis, Rossetos, Michopoulos, Ioannis, Dervenoulas, Georgios, Christodoulou, Christos, Douzenis, Athanasios“…All his psychopathological manifestations and laboratory findings normalized after the above-mentioned drugs’ discontinuation, and the administration of supportive medical care and lorazepam 2,5 mg/TID. …”
Publicado 2015
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69por Grabala, Pawel, Chamberlin, Kelly, Grabala, Michal, Galgano, Michael A., Helenius, Ilkka J.“…Methods: We conducted a retrospective study of 30 patients with SSCs, treated with HGT followed by posterior spinal fusion (PSF; Group 1, n = 18) or treated using a temporary MCGR as a TID followed by PSF (Group 2, n = 12). All patients underwent surgical treatment between 2016 and 2022. …”
Publicado 2023
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74por US. Department of Energy. Office of Energy Research. Office of Health and Environmental Research“…This standard is a revision of the NIM document, AEC Report TID- 20893 (Rev 4) dated July 1974. It includes all the addenda and errata items that were previously issued as well as numerous additional items to make the standard current with modern technology and manufacturing practice.…”
Publicado 1990
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75por Whitmore, J, Baumbaugh, A E, Elias, J E, Holm, S, Knickerbocker, K, Los, S, Rivetta, C, Ronzhin, A, Shenai, A, Yarema, R J, Zimmerman, T“…All front-end electronics must be qualified to survive this radiation environment with no degradation in performance. …”
Publicado 2002
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76por Busse, David, Simon, Philipp, Schmitt, Lisa, Petroff, David, Dorn, Christoph, Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm, Michelet, Robin, Wrigge, Hermann, Kloft, Charlotte“…A prolonged infusion of meropenem 2000 mg TID was sufficient for MIC ≤ 8 mg/L and all investigated ABW and CLCR(CG_ABW) when employing the PK/PD target %fT (> MIC) = 40. …”
Publicado 2021
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77“…In addition, we demonstrate that RPA limits inhibitory interactions of Hop2-Mnd1 and Rdh54/Tid1 that otherwise occur during assembly of Dmc1-ssDNA nucleoprotein filaments. …”
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80por Faccio, Federico“…Starting from the beginning of the 90s, a large effort has been dedicated at CERN and in the collaborating institutes to develop, produce and deploy Application-Specific Integrated Circuits (ASICs) tolerant to all types of radiation effects: Total Ionizing Dose (TID), Single Event Effects (SEE) and Displacement Damage (DD). …”
Publicado 2023
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