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68041por Babikian, Haig Yousef, Jha, Rajeev Kumar, Truong, Quang Lam, Nguyen, Lan Thi, Babikyan, Yusef, Nguyen, Hoa Thi, To, Thanh Long, Agus, Ali“…There was 100% cumulative mortality, that is, both challenged and contact pigs died in the positive control group on day 20 of infection. …”
Publicado 2021
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68042por Fenton, Lynda, Gribben, Ciara, Caldwell, David, Colville, Sam, Bishop, Jen, Reid, Martin, White, Jane, Campbell, Marion, Hutchinson, Sharon, Robertson, Chris, Colhoun, Helen M, Wood, Rachael, McKeigue, Paul M, McAllister, David A“…Severe covid-19 was defined as being admitted to intensive care or dying within 28 days of a positive test result or assigned covid-19 as a cause of death. …”
Publicado 2021
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68043por Machado, Isidro, Nieto Morales, María Gema, Cruz, Julia, Lavernia, Javier, Giner, Francisco, Navarro, Samuel, Ferrandez, Antonio, Llombart-Bosch, Antonio“…After a median follow-up of 90 months, 9.3% recurred, 11.3% metastasized, 10.3% died of disease and 76.2% were free of disease. TERT mutations were detected in 40.6% of the SFTs; the TP53 mutation was detected in 17%, and only 9.3% showed both mutations. …”
Publicado 2021
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68044por Birungi, Doreen, Aceng, Freda Loy, Bulage, Lilian, Nkonwa, Innocent Herbert, Mirembe, Bernadette Basuta, Biribawa, Claire, Okethwangu, Denis, Opio, Nixon Denis, Monje, Fred, Muwanguzi, David, Ndumu, Deo Birungi, Aruho, Robert, Lumu, Paul, Lutwama, Julius, Kwesiga, Benon, Ario, Alex Riolexus“…Three of the seven confirmed human cases died among humans. Results from testing animal blood samples obtained from Kiruhura district indicated that 44% (64/146) cattle, 46% (35/76) goats, and 45% (9/20) sheep tested positive for RVF. …”
Publicado 2021
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68045por Zhao-Fleming, Hannah H., Valencia Sanchez, Cristina, Sechi, Elia, Inbarasu, Jery, Wijdicks, Eelco F., Pittock, Sean J., Chen, John J., Wingerchuk, Dean M., Weinshenker, Brian G., Lopez-Chiriboga, Sebastian, Dubey, Divyanshu, Tillema, Jan-Mendelt, Toledano, Michel, Yadav, Hemang, Flanagan, Eoin P.“…All patients with MOGAD recovered, but 2 of 11 (18%) patients with AQP4-NMOSD died of the attack. For AQP4-NMOSD, Black race was overrepresented for attacks requiring ventilatory support vs those without these episodes (5 of 11 [45%] vs 88 of 457 [19%]; p = 0.045). …”
Publicado 2021
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68046“…From this group 115 (56%) children died during infancy and 89 (44%) infants survived. …”
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68047“…A higher proportion of COVID positive patients (66.7%) and COVID-confirmed deaths (83.3%) were of Hispanic ethnicity compared to patients without COVID diagnosis (53.0%, P = 0.23) and patients who died without COVID (31.6%, P = 0.06); however, this was not statistically significant. …”
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68048por Li Bassi, Gianluigi, Suen, Jacky Y., White, Nicole, Dalton, Heidi J., Fanning, Jonathon, Corley, Amanda, Shrapnel, Sally, Hinton, Samuel, Forsyth, Simon, Parsons, Rex, Laffey, John G., Fan, Eddy, Bartlett, Robert, Brodie, Daniel, Burrell, Aidan, Chiumello, Davide, Elhazmi, Alyaa, Grasselli, Giacomo, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Marwali, Eva, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Panigada, Mauro, Pelosi, Paolo, Torres, Antoni, Ng, Pauline Yeung, Ogino, Mark, Fraser, John F.“…RESULTS: One-thousand five-hundred eighty-seven patients were included in the survival analysis; 588 patients died in hospital within 28 days of commencing invasive mechanical ventilation (37%). …”
Publicado 2021
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68049por Fayed, Mohamed, Patel, Nimesh, Yeldo, Nicholas, Nowak, Katherine, Penning, Donald H, Vasconcelos Torres, Felipe, Natour, Abdul Kader, Chhina, Anoop“…Patients in the 0 to 9 SOFA group who were intubated later had 2.7 times the odds of dying during hospital admission compared to patients who were intubated early (CI, 1.09-6.67). …”
Publicado 2021
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68050Publicado 2022“…At day 14, 25 (37%) patients in the sarilumab and 26 (34%) patients in the usual care group needed ventilation or died, (median posterior hazard ratio [HR] 1·10; 90% CrI 0·69–1·74) with a posterior probability HR greater than 1 of 37·4%. …”
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68051por Salerno, Stephen, Messana, Joseph M., Gremel, Garrett W., Dahlerus, Claudia, Hirth, Richard A., Han, Peisong, Segal, Jonathan H., Xu, Tao, Shaffer, Dan, Jiao, Amy, Simon, Jeremiah, Tong, Lan, Wisniewski, Karen, Nahra, Tammie, Padilla, Robin, Sleeman, Kathryn, Shearon, Tempie, Callard, Sandra, Yaldo, Alexander, Borowicz, Lisa, Agbenyikey, Wilfred, Horton, Golden M., Roach, Jesse, Li, Yi“…RESULTS: Among a total of 498 169 Medicare patients undergoing dialysis (median [IQR] age, 66 [56-74] years; 215 935 [43.1%] women and 283 227 [56.9%] men), 60 090 (12.1%) had COVID-19, among whom 15 612 patients (26.0%) died. COVID-19 rates were significantly higher among Black (21 787 of 165 830 patients [13.1%]) and Hispanic (13 530 of 86 871 patients [15.6%]) patients compared with non-Black patients (38 303 of 332 339 [11.5%]), as well as patients with short (ie, 1-89 days; 7738 of 55 184 patients [14.0%]) and extended (ie, ≥90 days; 10 737 of 30 196 patients [35.6%]) nursing home stays in the prior year. …”
Publicado 2021
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68052por Acharya, Arpan, Pandey, Kabita, Thurman, Michellie, Klug, Elizabeth, Trivedi, Jay, Sharma, Kalicharan, Lorson, Christian L., Singh, Kamal, Byrareddy, Siddappa N.“…More than 207 million people have been infected globally, and 4.3 million have died due to this viral outbreak. While a few vaccines have been deployed, a SARS-CoV-2-specific antiviral for the treatment of COVID-19 is yet to be approved. …”
Publicado 2021
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68053por Afify, Shimaa, Eysa, Basem, Hamid, Fatma Abdel, Abo-Elazm, Omnia M, Edris, Mohamed A, Maher, Rabab, Abdelhalim, Ahmed, Abdel Ghaffar, Muhammad Mostafa, Omran, Dalia A, Shousha, Hend Ibrahim“…RESULTS: This retrospective cohort study included 125 patients with chronic hepatitis C and COVID-19 co-infection, of which 64 (51.20%) had liver cirrhosis and 40 (32.00%) died. Fever, cough, dyspnea, and fatigue were the most frequent symptoms in patients with liver cirrhosis. …”
Publicado 2021
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68054por Moreno, German Camacho, Valderrama, Carolina Duarte, Palacios, Jacqueline, Calvo, Luz Angela, Talavera, Ivy, Castañeda, Jaime Moreno, Cortes, Luz Yanet Maldonado, Jerez, Daniela, Romero, Carolina Garcia, Rodriguez, Karen Jimenez, Sanabria, Olga, Rodriguez, Yenny Marcela Elizalde, Monroy, Leidy, Duarte, Maria Cristina“…The rate of hospitalization for BP was 9/1000 children < 5 years, and 43 patients died. Case fatality rate was 1.7% among probable cases. …”
Publicado 2021
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68055por Hill-Ricciuti, Alexandra C, Walsh, Edward E, Greendyke, William G, Barrett, Angela, Alba, Luis, Branche, Angela, Falsey, Ann, Phillips, Matthew R, Choi, Yoonyoung, Finelli, Lyn, Saiman, Lisa“…CO-RSV controls were more likely to have pulmonary comorbidities than HA-RSV cases (46% vs. 31%, p=0.02). 38% of HA-RSV vs. 15% of CO-RSV subjects were hospitalized ≥15 days after their RSV-positive test (p=0.047). 14% of HA-RSV and 6% of CO-RSV subjects died (p=0.25). Among patients who survived, HA-RSV cases were more likely discharged to a skilled nursing or rehabilitation facility than CO-RSV controls (46% vs. 17%, p=0.04). …”
Publicado 2021
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68056por Foster, Catherine, Kumar, Shelley, Tocco, Elizabeth, Holzmann-Pazgal, Galit, Campbell, Judith R, Marquez, Lucila, Dutta, Ankhi“…Four children in each group died. Characteristics of Hospitalized Children with SARS-CoV-2 Infection by Weight Category [Image: see text] Abbreviations: ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit; MIS-C, multisystem inflammatory syndrome in children; MV, mechanical ventilation; NC, nasal cannula *Denotes statistically significant P-value a. …”
Publicado 2021
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68057por Del Carpio-Orantes, Luis, García-Méndez, Sergio, Zamudio-Severino, Gustavo Miguel, Sánchez-Díaz, Jesús Salvador, Navarrete-Espinosa, Benito, Rivera-Viñas, Miguel Ángel, Salas-González, Arturo, aguilar-silva, Andrés, Cruz-Albarrán, Sonia, Denis-Bravo, Jorge Luis, Esparza-Mora, Iván, González-Medel, Karem Samantha, Hernández-Zaleta, Nelyda Verania, López-Cruz, Edgar Alberto, Montano-Montiel, Laura Guadalupe, Morgado-Hernández, Jennifer Ivonne, Muñoz-Aguilar, José Alberto, Priego-Parra, Edson Irving, Reich-Sierra, Reynaldo, Sánchez-Jiménez, Noel Jhosimar, Tress-Uc, María Fernanda, Velázquez-Orozco, Paola, Contreras-Sánchez, Edna Rosario, Medrano-Rios, Luis Jaime, Ruiz-Castro, Enrique, Ortiz-Hernández, Manuel Alejandro“…The outcomes, 27 (90%) patients improved and there were 3 (10%) who died. Demographic Variables [Image: see text] Respiratory Variables [Image: see text] Results on SAFI and SaO(2) [Image: see text] CONCLUSION: Baricitinib therapy in these patients with severe COVID-19 pneumonia who present with severe hypoxemia and cytokine storm presented good results by improving clinical status and pulmonary failure, with patients being cared for at home and avoiding mechanical ventilation. …”
Publicado 2021
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68058por Miyayama, Shiro, Yamashiro, Masashi, Ikeda, Rie, Matsumoto, Junichi, Takeuchi, Kiyotaka, Sakuragawa, Naoko, Ueda, Teruyuki, Sanada, Taku, Notsumata, Kazuo, Terada, Takuro“…The 1-, 3-, 5-, and 7-year overall and recurrence-free survival rates in 175 patients, excluding those with Child–Pugh C class, who died of other malignancies, or who underwent combined RFA or hepatic resection, were 97.1 and 68.7, 82.8 and 34.9, 64.8 and 20.2, and 45.3 and 17.3%, respectively. …”
Publicado 2021
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68059por Qiu, Lianqun, Medeiros, L. Jeffrey, Tang, Guilin, Khanlari, Mahsa, Li, Shaoying, Konoplev, Sergej, Wang, Sa A., Yin, C. Cameron, Khoury, Joseph D., Wang, Wei, Miranda, Roberto N., Iyer, Swaminathan, You, M. James, Xu, Jie“…Eight of nine (90%) patients with leukemic ALK-negative ALCL died, and their overall survival was significantly shorter than that of the patients with non-leukemic disease (median 15.5 vs. 60 months, p = 0.001). …”
Publicado 2021
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68060por Akkoyun, Esra, Sotelo, Jesus, Cherry, Giselle, Bisceglia, Maria, Slone, Tamra, Aquino, Victor, Sue, Paul“…Among severe and critically ill children, six (86%) had underlying hematologic malignancies (5 HR ALL, 1 AML), and two (28%) a prior history of HSCT. Two children (4%) died. Thirty-six patients (78%) achieved documented clearance of SARS-CoV-2 by PCR, at median of 43.5 days (IQR 28.7-65.2). …”
Publicado 2021
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