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  1. 68461
    “…A considerable majority of patients survived throughout this period (92.8%), while five women died (7.2%). In fact, the OS was 31.7 ± 14.2 months and PFS was 30.2 ± 14.1 months. …”
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    An Innovative Non-Linear Prediction Model for Clinical Benefit in Women with Newly Diagnosed Breast Cancer Using Baseline FDG-PET/CT and Clinical Data
  2. 68462
    “…The median post-TB treatment follow-up was 6.4 years (IQR 3.4-9.0) and 233 (7.3%) patients died. Causes of death included cardiovascular disease and malignancy (n=56 or 24%, each) and HIV (n=22, 9.9%). …”
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    1877. Post-Tuberculosis Treatment Mortality in Georgia (2009-2018)
  3. 68463
    “…One patient (0.5%; infected with Omicron CH.1.1) with progressive neuromuscular disease needed high flow oxygen/non-invasive mechanical intervention and died on D18 (death deemed not COVID-19 related by investigator) (Table 2). …”
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    512. Interim Results of a Prospective Cohort Study to Monitor the Emergence of Resistance in Immunocompromised Non-Hospitalized Patients With COVID-19 Who Were Treated with Sotrovimab in Great Britain: LUNAR Study 
  4. 68464
    por Graham, Allen
    Publicado 1916
    “…High iodine contents produce rapid emaciation, at the same time resulting in differentiation even in tadpoles dying in 8 to 12 days. Low iodine contents result in differentiation at an earlier period than the controls. …”
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    A STUDY OF THE PHYSIOLOGICAL ACTIVITY OF ADENOMATA OF THE THYROID GLAND, IN RELATION TO THEIR IODINE CONTENT, AS EVIDENCED BY FEEDING EXPERIMENTS ON TADPOLES
  5. 68465
    por Foot, Nathan Chandler
    Publicado 1923
    “…—A side experiment was performed with five rabbits, two splenectomized and three controls, into which uniform doses of pneumococci were injected intravenously. They all died of septicemia after a few days. The results of this experiment strengthen the foregoing conclusions materially. …”
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    STUDIES ON ENDOTHELIAL REACTIONS : VIII. CHANGES IN THE DISTRIBUTION OF TUBERCLE BACILLI AND TUBERCLES IN THE ORGANS OF RABBITS FOLLOWING SPLENECTOMY.
  6. 68466
    por Blinks, L. R.
    Publicado 1936
    “….; smaller ones on the other hand, if following soon after, have a greatly increased effectiveness, the threshold for polarization falling considerably. The effect dies away, however, with very small inward currents, even as they continue to flow. …”
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    THE EFFECTS OF CURRENT FLOW ON BIOELECTRIC POTENTIAL : I. VALONIA
  7. 68467
    por Brand, Richard A.
    Publicado 2008
    “…J Bone Joint Surg Am. 1941;23:516–512. 4. Dr. Frank Dickson dies at age of 81. The Kansas City Times, Mo. January 20, 1964;Obituaries. 5. …”
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    The Use of Sulfathiazole in the Treatment of Subacute and Chronic Osteomyelitis*: Frank D. Dickson MD (1882–1964), Rex L. Diveley MD, Richard Kiene MD The 4th President of the AAOS 1935 (FDD)
  8. 68468
    por Brand, Richard A.
    Publicado 2008
    “…Despite infirmities in his last years (he had bilateral hip prostheses), he continued to be active, and died while giving lectures at the University of Kansas (“as he would have wished ‘with his boots on.’” [3]). …”
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    Clinical and Experimental Observations with Regard to the Injection of Certain Agents (Pregl’s Solution) into Chronic Arthritic Joints: J. E. M. Thomson MD (1889–1962) The 14th President of the AAOS 1946
  9. 68469
    Publicado 2013
    “…FINDINGS: 1206 children were randomly assigned to clinically driven (n=606) versus routine laboratory monitoring (n=600), and groups A (n=397), B (n=404), and C (n=405). 47 (8%) children on clinically driven monitoring versus 39 (7%) on routine laboratory monitoring had a new WHO stage 4 event or died (hazard ratio [HR] 1·13, 95% CI 0·73–1·73, p=0·59; non-inferiority criterion met). …”
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    Routine versus clinically driven laboratory monitoring and first-line antiretroviral therapy strategies in African children with HIV (ARROW): a 5-year open-label randomised factorial trial
  10. 68470
    “…All cases followed-up for 6 months to 9 years (average 75 ± 32 months), 2 patients with severe regurgitation died (1 case of massive cerebral infarction, and 1 case of heart failure after 6 years and 8 years, respectively), 2 cases lost access. …”
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    Application of Percutaneous Balloon Mitral Valvuloplasty in Patients of Rheumatic Heart Disease Mitral Stenosis Combined with Tricuspid Regurgitation
  11. 68471
    por Sánchez‐Luna, Manuel, Medrano, Constancio, Lirio, Julián, Suazo, José Antonio Hurtado, Peña, Manuela, López, Eduardo Narbona, Fernández, José Uberos, Jover, Enrique Blanca, Perales, Antonio Bonillo, Delgado, Javier Díes, Montes, Mª Ángeles Ortega, de la Cruz Moreno, Jesús, Tardío, Joaquín Ortiz, Esteban, Mª Victoria, Millán, Leticia, Peracaula, Carlos Salido, Trujillo, Gloria María Quesada, Pajares, José David Martínez, López, Simón Pedro Lubián, Aranda, Salvador Ariza, Faci, Mª Purificación Ventura, Guillén, Sofía Valle, Lozano, Olga Bueno, Gracia, Segundo Rite, Cabezas, Miguel Ángel García, Ramírez, Natalia Bejarano, Machado, Mª Carmen Fresneda, Gutiérrez, Andrés Martínez, Rodríguez, Sara Rellán, Temprano, Marianela Marcos, Vicente, Elena Ortega, Malfaz, Fernando Centeno, Martín, Laura San Feliciano, Escalero, Ana Remesal, Zaballos, Francisca Benito, Closa‐Monasterolo, Ricardo, Salvadó, Silvia Franch, Sanz, Israel Fernando Anquela, Castells, Joaquim Bosch, Fagundo, Alberto Trujillo, Malfaz, Emma Ametller, Fernández, Mario José Sánchez, Mir, Eduard Solé, Lletget, Wilfredo Coroleu, Carrera, Ignacio Arroyo, Perianes, María Taboada, Pico, Mª Luz Couce, Seara, María José Fernández, del Prado, Mª Yolanda Ruiz, Olive, Mª Luisa Poch, Maderuelo, Elena, Zeballos, Susana, Orozco, Ana Leal, Serrano, Cristina Ruíz, Omeñaca, Félix, Palomino, Esperanza Escribano, Guereta, Luis García, Jiménez, Vicente Bosch, Sánchez, José Diego Gutiérrez, Pidre, Manuel Cidrás, Sánchez, Natividad Viguria, Orayen, Concepción Goñi, Unceta‐Barrenechea, Ana Aguirre, Legorburu, Alberto Pérez, Ortuño, Mª José Palao, Crespo, Maribel Giner, Muñoz, Ángel González, Macián, Mª Isabel Izquierdo, Zafra, Rafael Gómez, Colunga, Juan Mayordomo, Zapico, Bárbara Montes, Varas, María Rosón, Matilla, María Mora, Herroz, Ignacio Oulego, Pereira, Mª Teresa Prada, Consuegra, Miguel Ángel Arias, Vilella, Laura Castells, Cazcarra, Jesús Antonio Mairal, Ruiz, Silvia Yévenes, de Terrassa, Consorci Sanitàri, Díez, Isabel Sáez, Reymundo, Mercedes García, López, Esther Piñán, Sarabia, Javier Fernández, Cáceres, Sofía Hernández, Lois, Mª Gloria López, Olivas, Cristina, Martin, Mª José Rivero, de las Heras Ibarra, Susana, Cuadrado, Mercedes, Amador, Jose Tomás Ramos, Martin, Sara Guillén, Díaz, Alfonso Cañete, Corvino, Julia Sopeña, –Puelles, Francisco Javier González‐Valcárcel Sánchez, Sirera, Jose Cambra, García, Begoña Pérez, Candel, Maria Isabel Jiménez, Calvo, Elisa Cueto, Guardia, Leonor, Casero, Julián Lirio, Galiana, Gemma Ginovart, Bernal, Esther López, de León, Lorenzo Sánchez, Ferrandez, Maria Jesus, Quiles, Jose Luis, de Elche, H., Rimblas, Maria, Capaces, Susana Larrosa, Joan de Reus, H. San
    Publicado 2016
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    Down syndrome as risk factor for respiratory syncytial virus hospitalization: A prospective multicenter epidemiological study
  12. 68472
    “…The incidences of AEs did not differ significantly (P > 0.05) between the 2 groups except for the headache and skin-related adverse events (the incidence of headache was higher in the intervention group than in controls; P < 0.05). No patient died during the study. CONCLUSION: In patients with type 2 diabetes mellitus (T2DM) inadequately controlled by metformin monotherapy, the addition of alogliptin contributed to clinically significant increases in pulmonary function through regulating glycemia and improving the imbalance of the oxidative-related substances in the serum, without increasing the incidence of hypoglycemia, dyslipidemia, dysarteriotony, and any notable increase in body weight.…”
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    The effect of alogliptin on pulmonary function in obese patients with type 2 diabetes inadequately controlled by metformin monotherapy
  13. 68473
    “…Of the live-born babies, 343 (6.9%) in the control arm and 303 (5.2%) in the intervention arm died in their first 28 days of life (risk ratio 0.76, 95% CI 0.64 to 0.90, p = 0.0018; risk difference −1.59%, 95% CI −2.63% to −0.54%), suggesting that there were 92 fewer deaths (95% CI 31 to 152) as a result of the intervention. …”
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    Community health promotion and medical provision for neonatal health—CHAMPION cluster randomised trial in Nagarkurnool district, Telangana (formerly Andhra Pradesh), India
  14. 68474
    “…Measures such as years of life lost (YLLs), which quantifies the number of years of life lost because the person dies prematurely due to a disease or injury, should be employed to better quantify the population impact. …”
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    Years of life lost due to traumatic brain injury in Europe: A cross-sectional analysis of 16 countries
  15. 68475
    “…In patients assessed for radiotherapy toxicity, was no difference in grade 3–4 oesophagitis between the groups (47 [19%] of 254 patients in the twice-daily group vs 47 [19%] of 246 in the once-daily group; p=0·85) and grade 3–4 radiation pneumonitis (4 [3%] of 254 vs 4 [2%] of 246; p=0·70). 11 patients died from treatment-related causes (three in the twice-daily group and eight in the once-daily group). …”
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    Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial
  16. 68476
    “…The three most common serious adverse events, representing 111 (39%) of all 285 serious adverse events recorded, were febrile neutropenia (27 [17%] of 155 serious adverse events in patients who received doxorubicin and 15 [12%] of 130 serious adverse events in patients who received gemcitabine and docetaxel, fever (18 [12%] and 19 [15%]), and neutropenia (22 [14%] and ten [8%]). 154 (60%) of 257 patients died in the intention-to-treat population: 74 (57%) of 129 patients in the doxorubicin group and 80 (63%) of 128 in the gemcitabine and docetaxel group. …”
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    Gemcitabine and docetaxel versus doxorubicin as first-line treatment in previously untreated advanced unresectable or metastatic soft-tissue sarcomas (GeDDiS): a randomised controlled phase 3 trial
  17. 68477
    “…Considering serious outcomes in patients ≥65, higher proportions of patients hospitalized with the H1N1 strain experienced intensive care unit (ICU) admission and need for mechanical ventilation, while higher proportions of patients hospitalized with B/Yamagata and H3N2 died within 30 days of admission. CONCLUSION: Comprehensive collection of surveillance data paired with NP specimens by the CIRN SOS Network was conducive to broader understanding of influenza strain activity and associated outcomes at the subtype and lineage level. …”
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    Epidemiology of Influenza Viruses in Canada over the 2011–2012 to 2013–2014 Seasons: A Study from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN)
  18. 68478
    “…In 83 participants in the treated population, there were 71 adverse events during the intervention, of which 21 (30%) were serious, and 81 adverse events during the washout periods, of which 26 (32%) were serious (p=0·31), including one patient who died in the second washout period. INTERPRETATION: RUSF providing 500 kcal/day results in small weight gains in children with sickle-cell disease. …”
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    Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial
  19. 68479
    “…FINDINGS: Between June 18, 2013, and April 10, 2015, we randomly assigned 1805 participants to treatment: 897 to RUSF and 908 to no-RUSF. 56 (3%) were lost-to-follow-up. 96 (10·9%, 95% CI 9·0–13·1) participants allocated to RUSF and 92 (10·3%, 8·5–12·5) to no-RUSF died within 24 weeks (hazard ratio 1·05, 95% CI 0·79–1·40; log-rank p=0·75), with no evidence of interaction with the other randomisations (both p>0·7). …”
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    Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial
  20. 68480
    Publicado 2011
    “…Of the 516 patients, bronchoplastic procedures and pulmonary artery reconstruction was carried out in 256 cases; lobectomy combined with resection and reconstruction of partial left atrium was performed in 41 cases; Double sleeve lobectomy combined with resection and reconstruction of super vena cava was carried out in 90 cases; Lobectomy combined with resection and reconstruction of diaphragm was performed in 3 cases; Double sleeve lobectomy combined with resection and reconstruction of partial left atrium was performed in 30 cases; Bronchoplastic procedures and pulmonary artery reconstruction combined with reconstruction of aorta sheath was carried out in 10 cases; Right pneumonectomy combined with resection and reconstruction partial left atrium, total right diaphragm with Dacron, and post cava and right liver vein was performed in one case; Lobectomy combined with resection and reconstruction of carina was carried out in 10 cases; Bronchoplastic procedures and pulmonary artery reconstruction combined with resection and reconstruction of carina and superior vane cava, or combined with superior vena cava and left atrium, or with carina and left atrium was performed in 55 cases in this series. Five patients died of operative complications and the operative mortality was 0.97%. …”
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    基于"分子分期"的局部晚期非小细胞肺癌"个体化外科治疗"的长期生存结果
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