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68681por Seidel, Danila, Cornely, Oliver, Zarrouk, Marouan, Koehler, Philipp, Meis, Jacques F, Salmanton-García, Jon, Vehreschild, Jörg Janne, Christner, Martin, Gräfe, Stefanie K, Falces-Romero, Iker, Lagrou, Katrien, Maertens, Johan, Reséndiz- Sharpe, Agustín, Racil, Zdenek, Weinbergerová, Barbora, Valerio, Maricela, Muñoz, Patricia, Blennow, Ola, Rammaert, Blandine, Ostojic, Alen, Govic, Yohann Le, Lass-Flörl, Cornelia, Rössler, Susann, van Dijk, Karin, de Jong, Nick, Steinmann, Jörg, Desoubeaux, Guillaume, Alakel, Nael, Klimko, Nikolay, Schalk, Enrico, Brenier-Pinchart, Marie-Pierre, Garcia-Vidal, Carolina, Bergeron, Anne, Cho, Sung-Yeon, Melchers, Willem J G, Vehreschild, Maria J G T, Verweij, Paul E“…Overall, all-cause mortality rate was higher for patients with azole-resistant compared to azole-susceptible IA (74.2% vs. 53.8%, log rank P=0.004), the 8 patients with an azole-resistant IA treated in the intensive care unit died within 1 month (Figure 1). Details on underlying disease and survival are given in Table 1. …”
Publicado 2020
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68682por Brown, Li-An K., Freemantle, Nick, Breuer, Judy, Dehbi, Hakim-Moulay, Chowdhury, Kashfia, Jones, Gemma, Ikeji, Felicia, Ndoutoumou, Amalia, Santhirakumar, Krishneya, Longley, Nicky, Checkley, Anna M., Standing, Joseph F., Lowe, David M.“…Proportion of participants who have died with COVID-19 related illness. Pharmacokinetic and pharmacodynamic analysis of favipiravir. …”
Publicado 2021
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68683por Galvez, Carlos, Nizamuddin, Imran, Tuchman, Emily, Doukas, Peter, Reddy, Neha, Altman, Jessica K., Winter, Jane N., Gordon, Leo I., Barth, Dylan, Hodgins, Nicole, Pro, Barbara, Ma, Shuo, Dinner, Shira, Frankfurt, Olga, Mehta, Jayesh, Singhal, Seema, Adekola, Kehinde, Moreira, Jonathan, Tanna, Sajal D, Wehbe, Firas, Karmali, Reem“…Four pts (6%) had thrombotic events and 31 (42%) received SARS-CoV-2-directed therapies. Sixteen pts (22%) died during the study period. Pts on active cancer treatment had higher rates of hospital admission (81% v 60%; p=0.05) and AKI (51% v 29%; p=0.04) but similar rates of death compared with pts not on active treatment (24% v 20%; p=0.66) (Table 3). …”
Publicado 2020
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68684por Pagnano, Katia B, Kok, Chung Hoow, Mauro, Michael J., Cortes, Jorge E., Evans, Nicola, Jiang, Qian, Milojkovic, Dragana, Moiraghi, Beatriz, Nicolini, Franck E., Ongondi, Matilda, Zackova, Daniela, Rea, Delphine, Hughes, Timothy P.“…At the data cut-off, from the 606 pts with known outcome, 48 pts died (8%) and 558 (92%) recovered. Age >75y (Fig 1A, p<0.001), comorbidities (Fig 1B, p=0.039), low income country (Fig 1C, p<0.001), advanced phase CML at time of COVID-19 (Fig 1D, p<0.001) had statistically significant association with overall survival (OS) in CML pts with COVID-19. …”
Publicado 2021
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68685por Sheats, Kameron J., Wilson, Rebecca F., Lyons, Bridget H., Jack, Shane P.D., Betz, Carter J., Fowler, Katherine A.“…PROBLEM/CONDITION: In 2018, approximately 68,000 persons died of violence-related injuries in the United States. …”
Publicado 2022
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68686por Wang, Emily, Kuhn, Theresa, Lahiri, Cecile, Nguyen, Minh, Ofotokun, Ighovwerha, Abraham, Rachael, Easley, Kirk, Mosunjac, Marina, Tadros, Talaat, Finneran, Catherine, Flowers, Lisa“…OBJECTIVES/GOALS: Cervical cancer is the fourth most common cancer among women worldwide, with approximately 570,000 newly diagnosed cases and 311,000 related deaths among women in 2018.In the United States, approximately 13,000 new cases of cervical cancer are diagnosed annually with approximately 4,000 women dying each year from cervical cancer. Nearly all cervical cancer is caused by oncogenic strains of the human papillomavirus (HPV). …”
Publicado 2020
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68687“…Among all reported malaria cases in 2018, a total of 251 (13.8%) were classified as severe malaria illness, and seven persons died from malaria. In 2018, CDC analyzed 106 P. falciparum-positive and four P. falciparum mixed species specimens for antimalarial resistance markers (although certain loci were untestable in some specimens); identification of genetic polymorphisms associated with resistance to pyrimethamine were found in 99 (98.0%), to sulfadoxine in 49 (49.6%), to chloroquine in 50 (45.5%), and to mefloquine in two (2.0%); no specimens tested contained a marker for atovaquone or artemisinin resistance. …”
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68688“…Among all reported cases in 2017, a total of 312 (14.4%) were classified as severe malaria illnesses, and seven persons died. In 2017, CDC analyzed 117 P. falciparum-positive and six P. falciparum mixed-species samples for antimalarial resistance markers (although certain loci were untestable in some samples); identification of genetic polymorphisms associated with resistance to pyrimethamine were found in 108 (97.3%), to sulfadoxine in 77 (69.4%), to chloroquine in 38 (33.3%), to mefloquine in three (2.7%), and to atovaquone in three (2.7%); no specimens tested contained a marker for artemisinin resistance. …”
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68689por Ip, Andrew, Mato, Anthony, Intrator, Jordan, Howard, Nicholas P, Petrillo, Alessandra, Vicioso, Rosalba, Sebti, Rani, Cicogna, Cristina, Magarelli, Gabriella, Leslie, Lori A., Goy, Andre H., Feldman, Tatyana A.“…Inflammatory markers at diagnosis showed median CRP 9.4 mg/dL (0.7-126, n=62) and ferritin of 966 ng/mL (96-14,511, n=42). 76 of 89 (85%) patients required hospitalization, 11 (12%) required mechanical ventilation, and 31 (Case Fatality Rate=35%) died. The overall survival of lymphoma patients is shown in Figure 1A. …”
Publicado 2020
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68690por Janapala, Rajesh naldu, jayaraj, joseph, Rass, bayan, Zarghamravanbakhsh, Paria, Sachmechi, issac“…Further his stay in the hospital was complicated by urinary tract infection with vancomycin-resistant enterococcus which was treated with linezolid. Later the patient died shortly due to progression of his primary malignancy. …”
Publicado 2020
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68691por Spanjaart, Anne Mea, Ljungman, Per, De La Camara, Rafael, Tridello, Gloria, Ortiz-Maldonado, Valentín, Urbano-Ispizua, Alvaro, Barba, Pere, Kwon, Mi, Caballero, Dolores, Sesques, Pierre, Bachy, Emmanuel, Di Blasi, Roberta, Thieblemont, Catherine, Calkoen, Friso, Mutsaers, Pim G.N.J., Maertens, Johan A., Giannoni, Livia, Nicholson, Emma, Collin, Matthew P., Vaz, Carlos Pinho, Metafuni, Elisabetta, Martínez-López, Joaquín, Dignan, Fiona, Ribera, Josep-Maria, Nagler, Arnon, Folber, František, Sanderson, Robin, Bloor, Adrian, Ciceri, Fabio, Knelange, Nina, Ayuk, Francis A., Kröger, Nicolaus, Kersten, Marie José, Mielke, Stephan“…At the time of analysis, 25 of the 56 patients had died (44.6%), most (23/25) due to COVID-19, resulting in a COVID-19 attributable mortality rate of 41%. …”
Publicado 2021
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68692por Marchesi, Francesco, Salmanton-García, Jon, Lopez-Garcia, Alberto, Dragonetti, Giulia, Sili, Uluhan, Glenthoej, Andreas, Buquicchio, Caterina, Mikulska, Malgorzata, Weinbergerova, Barbora, Busca, Alessandro, Corradini, Paolo, Hoenigl, Martin, Klimko, Nikolay N., Pagliuca, Antonio, Passamonti, Francesco, Köhler, Philipp, Cornely, Oliver, Pagano, Livio“…After a follow-up of 30 day from SARS-CoV-2 infection, 8 patients died (20%), with 7/8 deaths (87.5%) attributable to SARS-CoV-2. …”
Publicado 2021
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68693por Wiedmeier, Julia E., Iqbal, Madiha, Munoz, Javier, Bezerra, Evandro D., Garcia Robledo, Juan Esteban, Bansal, Radhika, Johnston, Patrick B., Hathcock, Matthew, Larsen, Jeremy T., Bergsagel, P. Leif, Wang, Yucai, Reeder, Craig B., Leis, Jose F., Fonseca, Rafael, Palmer, Jeanne M., Warsame, Rahma M, Kourelis, Taxiarchis, Hayman, Suzanne R., Dingli, David, Kapoor, Prashant, Kumar, Shaji, Durani, Urshila, Villasboas, Jose C., Paludo, Jonas, Bennani, N. Nora, Ansell, Stephen M., Castro, Januario E, Kharfan-Dabaja, Mohamed A., Lin, Yi, Vergidis, Paschalis, Murthy, Hemant S., Rosenthal, Allison C.“…Furthermore, of the 13 patients that survived COVID-19, they received CAR T an average of 416 days prior to COVID-19 infection (median = 337, range = 54 - 1406); the 6 patients who died from COVID-19 had received CAR T an average of 250 days prior to COVID-19 infection (median = 164, range = 7 - 846). …”
Publicado 2021
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68694por Roeker, Lindsey E, Scarfo, Lydia, Chatzikonstantinou, Thomas, Abrisqueta, Pau, Eyre, Toby A., Cordoba, Raul, Muntañola Prat, Ana, Villacampa, Guillermo, Leslie, Lori A., Koropsak, Michael, Quaresmini, Giulia, Allan, John N., Furman, Richard R., Bhavsar, Erica B, Pagel, John M., Hernandez-Rivas, Jose Angel, Patel, Krish, Motta, Marina, Bailey, Neil, Miras, Fatima, Lamanna, Nicole, Alonso, Rosalia, Osorio-Prendes, Santiago, Vitale, Candida, Kamdar, Manali, Baltasar, Patricia, Österborg, Anders, Hanson, Lotta, Baile, Mónica, Rodríguez-Hernández, Ines, Valenciano, Susana, Popov, Viola Maria, Barez Garcia, Abelardo, Alfayate, Ana, Oliveira, Ana C, Eichhorst, Barbara, Quaglia, Francesca M., Reda, Gianluigi, Lopez Jimenez, Javier, Varettoni, Marzia, Marchetti, Monia, Romero, Pilar, Riaza Grau, Rosalía, Munir, Talha, Zabalza, Amaya, Janssens, Ann, Niemann, Carsten U, Perini, Guilherme Fleury, Delgado, Julio, Yanez San Segundo, Lucrecia, Gómez Roncero, Ma Isabel, Wilson, Matthew, Patten, Piers, Marasca, Roberto, Iyengar, Sunil, Seddon, Amanda, Torres, Ana, Ferrari, Angela, Cuéllar-García, Carolina, Wojenski, Daniel, El-Sharkawi, Dima, Itchaki, Gilad, Parry, Helen, Mateos-Mazón, Juan José, Martinez-Calle, Nicolas, Ma, Shuo, Naya, Daniel, Van Der Spek, Ellen, Seymour, Erlene K., Gimeno Vázquez, Eva, Rigolin, Gian Matteo, Mauro, Francesca Romana, Walter, Harriet S, Labrador, Jorge, De Paoli, Lorenzo, Laurenti, Luca, Ruiz, Elena, Levin, Mark-David, Šimkovič, Martin, Špaček, Martin, Andreu, Rafa, Walewska, Renata, Perez-Gonzalez, Sonia, Sundaram, Suchitra, Wiestner, Adrian, Cuesta, Amalia, Broom, Angus, Kater, Arnon P., Muiña, Begoña, Velasquez, César A, Ujjani, Chaitra S., Seri, Cristina, Antic, Darko, Bron, Dominique, Vandenberghe, Elisabeth, Chong, Elise A., Lista, Enrico, García, Fiz Campoy, Del Poeta, Giovanni, Ahn, Inhye, Pu, Jeffrey J., Brown, Jennifer R, Soler Campos, Juan Alfonso, Malerba, Lara, Trentin, Livio, Orsucci, Lorella, Farina, Lucia, Villalon, Lucia, Vidal, Maria Jesus, Sanchez, Maria Jose, Terol, Maria Jose, De Paolis, Maria Rosaria, Gentile, Massimo, Davids, Matthew S., Shadman, Mazyar, Yassin, Mohamed A, Foglietta, Myriam, Jaksic, Ozren, Sportoletti, Paolo, Barr, Paul M., Ramos, Rafael, Santiago, Raquel, Ruchlemer, Rosa, Kersting, Sabina, Huntington, Scott F., Herold, Tobias, Herishanu, Yair, Thompson, Meghan C., Lebowitz, Sonia, Ryan, Christine, Jacobs, Ryan W., Portell, Craig A., Isaac, Krista, Rambaldi, Alessandro, Nabhan, Chadi, Brander, Danielle M., Montserrat, Emili, Rossi, Giuseppe, Garcia-Marco, Jose A., Coscia, Marta, Malakhov, Nikita, Fernandez-Escalada, Noemi, Skånland, Sigrid Strand, Coombs, Callie C., Ghione, Paola, Schuster, Stephen J., Foà, Robin, Cuneo, Antonio, Bosch, Francesc, Stamatopoulos, Kostas, Ghia, Paolo, Mato, Anthony R., Patel, Meera“…The primary endpoint of this study was to estimate the case fatality rate (CFR), defined as the proportion of pts who died among all pts hospitalized with COVID-19. Chi-squared test was used to compare frequencies; univariable and multivariable analyses utilized Cox regression. …”
Publicado 2020
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