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  1. 2421
  2. 2422
  3. 2423
    “…Three dedicated approaches to the calculation of the risk-adjusted net present value (rNPV) in drug discovery projects under different assumptions are suggested. …”
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  4. 2424
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  6. 2426
    “…We identified challenges and limitations of clinical trials which reduced the generalizability and the universal adoption of key interventions. We present an international perspective regarding current sedation practice and a blueprint for future research, which seeks to avoid known limitations and generate much-needed high-level evidence to better guide clinicians' management and therapeutic choices of sedative agents.…”
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  7. 2427
    “…Moreover, a great improvement in high-throughput “omic” techniques has presented considerable opportunities for the identification of new biomarkers. …”
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  8. 2428
  9. 2429
    “…The history and evolution of these procedures, as well as the present status and future directions of robotic cardiac surgery, are presented in this review.…”
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  10. 2430
    “…Transmission of dengue is now present in every World Health Organization (WHO) region of the world and more than 125 countries are known to be dengue endemic. …”
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  11. 2431
  12. 2432
    por Choi, Bernard C. K.
    Publicado 2012
    “…This paper provides a review of the past, present, and future of public health surveillance—the ongoing systematic collection, analysis, interpretation, and dissemination of health data for the planning, implementation, and evaluation of public health action. …”
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  13. 2433
  14. 2434
    “…Given that many routine applications of plant DNA fingerprinting still rely on PCR-based markers, we here refer to these methods as “DNA fingerprinting in the present”, and include numerous examples in the present review. …”
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  19. 2439
    “…Many prophages and prophage-like elements present in sequenced bacterial genomes, such as Bifidobacteria, Lactococcus and Streptococcus, have been described. …”
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  20. 2440
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