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1por Mittendorf, Elizabeth A., Ardavanis, Alexandros, Litton, Jennifer K., Shumway, Nathan M., Hale, Diane F., Murray, James L., Perez, Sonia A., Ponniah, Sathibalan, Baxevanis, Constantin N., Papamichail, Michael, Peoples, George E.“…While the overall ITT analysis did not demonstrate benefit to vaccination, this trial confirmed that the GP2 vaccine is safe and suggests that vaccination may have clinical activity, particularly in patients with HER2 overexpression who received the full vaccine series (ie per-treatment group).…”
Publicado 2016
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2por Brown, Tommy A., Mittendorf, Elizabeth A., Hale, Diane F., Myers, John W., Peace, Kaitlin M., Jackson, Doreen O., Greene, Julia M., Vreeland, Timothy J., Clifton, G. Travis, Ardavanis, Alexandros, Litton, Jennifer K., Shumway, Nathan M., Symanowski, J., Murray, James L., Ponniah, Sathibalan, Anastasopoulou, E. A., Pistamaltzian, N. F., Baxevanis, Constantin N., Perez, Sonia A., Papamichail, Michael, Peoples, George E.“…PURPOSE: AE37 and GP2 are HER2 derived peptide vaccines. AE37 primarily elicits a CD4+ response while GP2 elicits a CD8+ response against the HER2 antigen. …”
Publicado 2020
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3por Sui, Xin, Frey, Beat, Yang, Libin, Liu, Yingnan, Zhang, Rongtao, Ni, Hongwei, Li, Mai-He“…The most abundant subgroups of Acidobacteria accounted for 31% (Gp1), 5% (Gp2), 12% (Gp3), 2% (Gp4), 5% (Gp6), and 2% (Gp7) in soils within eight successional series. …”
Publicado 2022
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4“…Once this has been achieved, sequences in the filovirus GP(2) subunit mediate viral/cellular membrane fusion via mechanisms similar to those previously described for other enveloped viruses. …”
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5por Jiang, Yifeng, Tong, Wu, Yu, Lingxue, Li, Liwei, Gao, Fei, Li, Guoxin, Liu, Changlong, Chen, Pengfei, Shen, Qi, Zhang, Yujiao, Zhou, Yanjun, Tong, Guangzhi“…Among 9 PRRSV attenuated series, consistent amino acid changes during PRRSV attenuation were found in NSP4, NSP9, GP2, E, GP3 and GP4. …”
Publicado 2021
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6por Bolken, Tove′ C., Laquerre, Sylvie, Zhang, Yuanming, Bailey, Thomas R., Pevear, Daniel C., Kickner, Shirley S., Sperzel, Lindsey E., Jones, Kevin F., Warren, Travis K., Amanda Lund, S., Kirkwood-Watts, Dana L., King, David S., Shurtleff, Amy C., Guttieri, Mary C., Deng, Yijun, Bleam, Maureen, Hruby, Dennis E.“…Drug resistant variants were isolated, suggesting that these compounds act through inhibition of a viral protein, the viral glycoprotein (GP2), and not through cellular toxicity mechanisms. …”
Publicado 2006
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7por Toyama, Sakiko, Honda, Tomoko, Iwabuchi, Sadahiro, Hashimoto, Shinichi, Yamaji, Kenzaburo, Tokunaga, Yuko, Matsumoto, Yusuke, Kawaji, Hideya, Miyazaki, Takashi, Kikkawa, Yoshiaki, Kohara, Michinori“…We established a method for performing spatial transcriptomics using the Visium system in the mouse nasal cavity and analyzed gene expression profiles within the nasal cavity after intranasal vaccination. Glycoprotein 2 (Gp2)-, SRY-box transcription factor 8 (Sox8)-, or Spi-B transcription factor (Spib)-expressing cells were increased in the nasal passage (NP) region at 3–6 hr after SARS-CoV-2 spike protein and CVP (S-CVP) vaccination. …”
Publicado 2023
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8por Drumright, Lydia, Frost, Simon D., Catchpole, Mike, Harrison, John, Atkins, Mark, Parker, Penny, Elliot, Alex J., Fleming, Douglas M., Holmes, Alison H.“…There may also be underreporting of or delays in reporting ILI in the community, for example in the UK those with mild illness are less likely to see a GP (2), and visits generally occur two or more days after onset of symptoms (3). …”
Publicado 2013
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