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  1. 2741
    por Eggink, Laura L, Hoober, J Kenneth
    Publicado 2009
    “…Phage particles that were eluted from the lectin with free GalNAc were considered to have been bound to a GalNAc-binding site. …”
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    A biologically active peptide mimetic of N-acetylgalactosamine/galactose
  2. 2742
    “…Knockdown of GalNAc4S-6ST in LLC cells resulted in a reduction in the proportion of E-units, in adhesiveness to extracellular matrix adhesion molecules and in proliferation in vitro. …”
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    Expression of N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase Involved in Chondroitin Sulfate Synthesis Is Responsible for Pulmonary Metastasis
  3. 2743
    por Domenech, Mirian, García, Ernesto
    Publicado 2017
    “…It is well known that the Helix pomatia (edible snail) agglutinin (HPA) lectin shows specificity for terminal αGalNAc residues present, among other locations, in the Forssman pentasaccharide (αGalNAc1→3βGalNAc1→3αGal1→4βGal1→4βGlc). …”
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    Fluorescence Imaging of Streptococcus pneumoniae with the Helix pomatia agglutinin (HPA) As a Potential, Rapid Diagnostic Tool
  4. 2744
    “…A previous investigation revealed that genetic divergence among Hainan isolates of PRSV has allowed the virus to overcome the CP-mediated transgenic resistance. …”
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    Use of RNAi technology to develop a PRSV-resistant transgenic papaya
  5. 2745
    “…N-Acetylhexosamine oligosaccharides terminated with GalNAc act as selective ligands of galectin-3, a biomedically important human lectin. …”
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    The β-N-Acetylhexosaminidase in the Synthesis of Bioactive Glycans: Protein and Reaction Engineering
  6. 2746
    “…We found nine potential signatures of selection detected simultaneously by two methods, annotated 22 genes in Hainan pigs, when Baoshan pigs were used as the reference group. …”
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    Genome-Wide Signatures of Selection Detection in Three South China Indigenous Pigs
  7. 2747
    “…PB_3262 was characterized as a novel 4-O-endosulfatase that can effectively and specifically hydrolyze the 4-O-sulfate group of disaccharide GlcUAβ1–3GalNAc(4-O-sulfate) but not GlcUAβ1–3GalNAc(4,6-O-sulfate) and IdoUAα1–3GalNAc(4-O-sulfate) in CS/DS oligo-/polysaccharides, which is very different from the identified 4-O-endosulfatases in the substrate profile. …”
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    Identification and Action Patterns of Two Chondroitin Sulfate Sulfatases From a Marine Bacterium Photobacterium sp. QA16
  8. 2748
    “…To assess the functional interactions between sulfatide and gangliosides, CST(−/−) and GalNAc-T(−/−) genotypes were interbred. CST(−/−)× GalNAc-T(−/−) mice develop normally to postnatal day 10 (P10), but all die between P20 and P25, coinciding with peak myelination. …”
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    Glial Sulfatides and Neuronal Complex Gangliosides Are Functionally Interdependent in Maintaining Myelinating Axon Integrity
  9. 2749
    por Yin, Zi-Wei, Li, Li-Zhen, Zhao, Mei-Jun
    Publicado 2012
    “…Two new species, Pselaphodes linae Yin & Li, sp. n. (Hainan, Fujian) and Pselaphodes shii Yin & Li, sp. n. …”
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    Two new species of Pselaphodes Westwood and new record of Taiwanophodes minor Hlaváč from South China (Coleoptera, Staphylinidae, Pselaphinae)
  10. 2750
    “…RESULTS: Median weight gain was 4.5 kg in gainers and median weight loss was 8.5 kg in losers. …”
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    Extremes of both weight gain and weight loss are associated with increased incidence of heart failure and cardiovascular death: evidence from the CANVAS Program and CREDENCE
  11. 2751
    “…Galactose and N-acetylgalactosamine (GalNAc) are sugars of great importance for the amoebae, they attach to the host mucus and enterocytes via their well-studied Gal/GalNAc specific lectin, they carry galactose residues in their surface glycans, and they cleave GalNAc from host mucins. …”
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    Molecular characterisation of Entamoeba histolytica UDP-glucose 4-epimerase, an enzyme able to provide building blocks for cyst wall formation
  12. 2752
    “…The 7.6 Å structure of a desensitized kainate receptor shows how these changes accommodate channel closing. …”
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    Structural mechanism of glutamate receptor activation and desensitization
  13. 2753
    por Yang, Yuxia, Qi, Yaqing, Yang, Xingke
    Publicado 2018
    “…(China: Zhejiang), F. hainana sp. n. (China: Hainan) and F. laticollis sp. n. (China: Hainan), which are illustrated with the habitus and aedeagus of the male, the abdominal sternite VIII and the internal genitalia of the female. …”
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    Four new species of Fissocantharis Pic, 1921 (Coleoptera, Cantharidae) from China
  14. 2754
    Publicado 2021
    “…Galina A. Melnichenko is a famous Russian scientist-endocrinologist, one of the leading in the country, author and head of fundamental and applied research. …”
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    К юбилею академика РАН Галины Афанасьевны Мельниченко
  15. 2755
    “…The greatest ECM accumulation was observed with 3,4,6-O-Bu(3)GalNAc. In contrast, mesenchymal stem cells (MSCs) exposed to 3,4,6-O-Bu(3)GalNAc exhibited a dose dependent decrease in chondrogenic differentation as indicated by decreased ECM accumulation. …”
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    Differential Response of Chondrocytes and Chondrogenic-Induced Mesenchymal Stem Cells to C1-OH Tributanoylated N-Acetylhexosamines
  16. 2756
    “…Deficient glycosylation in the GALE knockout cell line could be rescued by the addition of galactose and N-acetylgalactosamine (GalNAc) to the cell culture media. However, when key enzymes of the galactose/GalNAc salvage pathways were disrupted in tandem (GALE+GALK1 or GALE+GALK2), O-glycosylation was eliminated and could not be rescued by the addition of either galactose plus GalNAc or UDP-galactose plus UDP-GalNAc. …”
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    HEK293T cell lines defective for O-linked glycosylation
  17. 2757
    “…By analyzing tumor tissues, we showed that patients with high ST6GALNAC1 and IL-6 mRNA expression were BCG responders. …”
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    Expression of sialyl-Tn sugar antigen in bladder cancer cells affects response to Bacillus Calmette Guérin (BCG) and to oxidative damage
  18. 2758
    “…RESULTS: We found that systemic administration of hepatocyte-targeting GalNAc-Stk25 ASO in obese mice effectively ameliorated steatosis, inflammatory infiltration, hepatic stellate cell activation, nutritional fibrosis, and hepatocellular damage in the liver compared with mice treated with GalNAc-conjugated nontargeting ASO, without any systemic toxicity or local tolerability concerns. …”
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    Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease
  19. 2759
    “…FINDINGS: The integrity of the BBB in the epileptic region of DRE patients and kainate mouse models were demonstrated. LRP1 expression levels in the epileptic foci of DRE patients and kainate models were 1.70–2.38 and 2.32–3.97 folds higher than in the control brain tissues, respectively. …”
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    Imaging epileptic foci in mouse models via a low-density lipoprotein receptor-related protein-1 targeting strategy
  20. 2760
    “…Our results show that in macrophages, the uptake rate of PS-ASOs did not significantly differ from that of GalNAc-PS-ASOs. However, in hepatocytes, GalNAc-PS-ASOs exhibited a peripheral uptake distribution compared to a polar uptake distribution observed in macrophages. …”
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    Differential Uptake of Antisense Oligonucleotides in Mouse Hepatocytes and Macrophages Revealed by Simultaneous Two-Photon Excited Fluorescence and Coherent Raman Imaging
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