“…SeviL is a recently isolated lectin found to bind to the linear saccharides of the ganglioside GM1b (Neu5Ac[Formula: see text] (2-3)Gal[Formula: see text] (1-3)GalNAc[Formula: see text] (1-4)Gal[Formula: see text] (1-4)Glc) and its precursor, asialo-GM1 (Gal[Formula: see text] (1-3)GalNAc[Formula: see text] (1-4)Gal[Formula: see text] (1-4)Glc). …”
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“…The successes achieved using GalNAc-siRNAs have paved the way for developing RNAi-based delivery strategies that can target extrahepatic diseases including cancer. …”
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“…The area under the ROC curve was excellent against the PAINAD cut-off (≥0.8) but acceptable or less than acceptable for the other two standards. …”
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“…In this work, we show that cultured cortical neurons increased aerobic glycolysis in response to the inhibition of oxidative phosphorylation by oligomycin or to a kainate pulse. Such an increase was prevented by blocking the endogenous Aβ tone and re-established by the exogenous addition of synthetic Aβ monomers. …”
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“…Shanlan upland rice, a kind of unique rice germplasm in Hainan Island, was used to evaluate genetic diversity and association between SSR markers and agronomic traits. …”
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“…In the benign meningioma cell line, glycation led to differences in expression of sialyltransferases (ST3GAL1/2/3/5/6, ST6GAL1/2, ST6GALNAC2/6, and ST8SIA1/2), which are known to play a role in tumor progression. …”
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“…In vivo, a GalNAc-conjugated siRNA with a 1-nt bulge at position 14 of the guide strand was as active as the perfectly complementary siRNA. …”
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“…Therefore, the objective of this cross-sectional study was to evaluate the associations between immunoglobulins and depressive symptoms in Chinese older adults. RESULTS: The China Hainan Centenarian Cohort Study (CHCCS) provides a significant population-based sample of older adults in Hainan, China. …”
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“…Here, inter-annual changes in vegetation dynamics during 2000–2020, contributions of climate change (CC) and human activities (HA) to vegetation dynamics, and sustainability of vegetation dynamics in the future were determined in Gannan Prefecture (a typical alpine region in the Tibetan Plateau), China. …”
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“…The compounds were examined in the patch clamp experiments for their influence on the kainate-induced currents, and 10 of them were found to have potentiating properties. …”
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“…O-glycosylation, a crucial post-translational modification, is one such pathway that can lead to multiple isoforms of glycoproteins. The Tn (GalNAc-O-Ser/Thr) and Sialyl Tn (STn; Neu5Ac-GalNAc-O-Ser/Thr) antigens resulting from the incomplete synthesis of fully branched O-glycan chains on proteins contribute to disease progression in the pancreas and other gastrointestinal cancers. …”
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“…The Entamoeba histolytica antigen (GALNAC lectin) and serum antibodies were assessed using specific ELISAs (TECHLAB, Virginia, USA). …”
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“…The light REE enrichment and stable content of heavy REE with large negative Eu anomalies indicate that they were probably derived from Hainan Island. The reconstructed provenance evolution model showed that the Red River Source (RRS) provided sedimentary materials for the Central Depression of Yinggehai Basin from the Oligocene to the Pliocene, and Hainan Island Source (HIS) was also one of the sources for sediments deposited in the Central Depression of Yinggehai Basin during the Miocene. …”
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“…The loss of negatively charged sialic acids resulted only in a minor effect on CCL3-induced signal transduction. The enzymes GalNAc-T1 and GalNAc-T11 were shown to be involved in the process of chemokine receptor O-glycosylation. …”
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“…Altogether, nine genera (Calamoncosis, Eribolus, Gaurax, Incertella, Speccafrons, Trachysiphonella, Chloropsina, Eutropha, and Lagaroceras) and 46 species are recorded for the first time from Turkey.…”
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“…The observation from NGS was confirmed for only one cytosine located near the St6galnac5 gene, though this was with the opposite effect. …”
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“…We identified that genes related to the GalNAc metabolism pathway were enriched in the genomes of all five isolates and 16 Erysipelotrichaceae strains downloaded from GenBank, suggesting the importance of GalNAc metabolism in Erysipelotrichaceae strains. …”
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“…Two new Chinese species of Derops are described: Derops hainanus sp. n. from Hainan and Derops yunnanus sp. n. from Yunnan. Females of Derops punctipennis Schülke and Derops schillhammeri Schülke are described for the first time and new provinces records of Derops smetanai Schülke and Derops dingshanus Watanabe are reported. …”
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“…Chemical investigation of the EtOH extract of the fresh stem of Aquilaria sinensis collected in Hainan Province of China resulted in the isolation of a new benzenoid, named aquilarin A (1), together with two known compounds balanophonin (2) and (+)-lariciresinol (3). …”
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“…NEW INFORMATION: Clubiona milingae is redescribed and illustrated based on new material from the type locality and the new distribution region (Jianfeng Mountains and Limu Mountains of Hainan Island, China). The female is reported for the first time.…”
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