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3341por Wittmann, Alexandra, Lamprinaki, Dimitra, Bowles, Kristian M., Katzenellenbogen, Ewa, Knirel, Yuriy A., Whitfield, Chris, Nishimura, Takashi, Matsumoto, Naoki, Yamamoto, Kazuo, Iwakura, Yoichiro, Saijo, Shinobu, Kawasaki, Norihito“…H. alvei LPS induced higher levels of TNFα and IL-10 from mouse bone marrow-derived dendritic cells (BM-DCs), when compared with Salmonella enterica O66 LPS, which has a repeat of [-Gal-α1,6-Gal-α1,4-[Glc-β1,3]GalNAc-α1,3-GalNAc-β1,3-]. In a cell-based reporter assay, Dectin-2 was shown to recognize H. alvei LPS. …”
Publicado 2016
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3342por Sharma, Aditi, Lee, Seung-Hwan, Lim, Dajeong, Chai, Han-Ha, Choi, Bong-Hwan, Cho, Yongmin“…Amongst the Asian breeds Hainan, which is an indicine breed, had the lowest gene diversity while Yanbian had the highest followed by Mongolian and Korean cattle. …”
Publicado 2016
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3343por Pearce, Patrice S., Wu, Yijen, Rapuano, Amedeo, Kelly, Kevin M., de Lanerolle, Nihal, Pan, Jullie W.“…Although there was no difference in kainate dosing or seizure count between them, the metabolic pattern of injury was different. …”
Publicado 2016
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3344Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptorspor Bretin, Sylvie, Louis, Caroline, Seguin, Laure, Wagner, Stéphanie, Thomas, Jean-Yves, Challal, Sylvie, Rogez, Nathalie, Albinet, Karine, Iop, Fabrice, Villain, Nadège, Bertrand, Sonia, Krazem, Ali, Bérachochéa, Daniel, Billiald, Stéphanie, Tordjman, Charles, Cordi, Alex, Bertrand, Daniel, Lestage, Pierre, Danober, Laurence“…S 47445 enhanced glutamate’s action at AMPA receptors on human and rat receptors and was inactive at NMDA and kainate receptors. Potentiation did not differ among the different AMPA receptors subtypes (GluA1/2/4 flip and flop variants) (EC(50) between 2.5–5.4 μM), except a higher EC(50) value for GluA4 flop (0.7 μM) and a greater amount of potentiation on GluA1 flop. …”
Publicado 2017
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3345por Severino, Paulo F., Silva, Mariana, Carrascal, Mylene, Malagolini, Nadia, Chiricolo, Mariella, Venturi, Giulia, Barbaro Forleo, Roberto, Astolfi, Annalisa, Catera, Mariangela, Videira, Paula A., Dall’Olio, Fabio“…NMIBC expresses two tumor-associated O-linked carbohydrates: the disaccharide (Galβ1,3GalNAc) Thomsen-Friedenreich (T) antigen, and its sialylated counterpart (Siaα2,3Galβ1,3GalNAc) sialyl-T (sT), synthesized by sialyltransferase ST3GAL1, whose roles in BCG response are unknown. …”
Publicado 2018
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3346por Byun, Young-Jin, Lee, Chul Young, Kim, Myeong Hyeon, Jung, Dae Yun, Han, Jeong Hee, Jang, Insurk, Song, Young Min, Park, Byung-Chul“…RESULTS: In Exp. 1, fecal consistency (diarrhea) score (FCS) was less for the ZnO-2500 and SZ-200 groups than for the SZ-100 group (P < 0.05), with no difference between the SZ-100 and ZnO-100 groups. Both average daily gain (ADG) and gain:feed ratio were less for the SZ-200 group than for the ZnO-2500 group, with no difference between the ZnO-100 group and SZ-100 or SZ-200 group. …”
Publicado 2018
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3347por Yang, Bo-Seok, Kim, Myeong Hyeon, Choi, Jung-Seok, Jin, Sang Keun, Park, Man-Jong, Song, Young-Min, Lee, Chul Young“…HP and MP, with no difference between the HP and MP groups; the gain:feed ratio was less for the LP vs. MP group. Backfat thickness was greater for the LP vs. …”
Publicado 2019
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3348“…Furthermore, aMD simulations revealed that for both oligosaccharides in the free form, (4)C(1) and (1)C(4) puckers were sampled for all but GalNAc monosaccharides, while either the (4)C(1) (GlcNAc, Gal, GalNAc) or (1)C(4) (Fuc2, Fuc3) pucker was sampled in the CT-bound forms. …”
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3349por Berger, Toni C., Vigeland, Magnus D., Hjorthaug, Hanne S., Nome, Cecilie G., Taubøll, Erik, Selmer, Kaja K., Heuser, Kjell“…Hippocampi contralateral to the injection site from eight kainate-injected and eight sham mice were extracted and shock frozen at 24 h post-injection. …”
Publicado 2020
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3350por Alqurashi, Roaya S., Yee, Audrey S., Malone, Taylor, Alrubiaan, Sumaiah, Tam, Mary W., Wang, Kai, Nandedwalla, Rozena R., Field, Wesley, Alkhelb, Dalal, Given, Katherine S., Siddiqui, Raghib, Baleja, James D., Paulson, K. Eric, Yee, Amy S.“…Here, we identify a transient program of molecular and metabolic signaling in the early epileptogenic period, centered on day five following SE in the pre-clinical kainate or pilocarpine models of temporal lobe epilepsy. …”
Publicado 2021
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3351por Wang, Jing, Tang, Xuxiao, Chu, Qiulu, Zhang, Mengyu, Zhang, Yingzhong, Xu, Baohua“…Guangning of Guangdong (L6), Yunan of Guangdong (L7), Xingning of Guangdong (L9), Tianhe of Guangdong (L10), Xuwen of Guangdong (L11), and Xiuying of Hainan (L18) were in another group where the annual average temperatures are relatively high, and the altitudes are low. …”
Publicado 2022
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3352por Gane, Edward, Yuen, Man‐Fung, Kim, Dong Joon, Chan, Henry Lik‐Yuen, Surujbally, Bernadette, Pavlovic, Vedran, Das, Sudip, Triyatni, Miriam, Kazma, Remi, Grippo, Joseph F., Buatois, Simon, Lemenuel‐Diot, Annabelle, Krippendorff, Ben‐Fillippo, Mueller, Henrik, Zhang, Yuchen, Kim, Hyung Joon, Leerapun, Apinya, Lim, Tien Huey, Lim, Young‐Suk, Tanwandee, Tawesak, Kim, Won, Cheng, Wendy, Hu, Tsung‐Hui, Wat, Cynthia“…BACKGROUND AND AIMS: RO7062931 is an N‐acetylgalactosamine (GalNAc)‐conjugated single‐stranded locked nucleic acid oligonucleotide complementary to HBV RNA. …”
Publicado 2021
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3353por Jiang, Yingying, Xu, Tingling, Mao, Fan, Miao, Yu, Liu, Botao, Xu, Liyuan, Li, Lingni, Sternbach, Nikoletta, Zhou, Maigeng, Fan, Bifa“…Guizhou, Hainan, Xinjiang, Beijing, and Guangdong display a high burden of chronic pain. …”
Publicado 2022
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3354“…PCA of common peaks of 18 batches of R. tanguticum indicated that R. tanguticum grown in Gannan and Qinghai had a tendency to separate t[2], however this trend was not noticeable. …”
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3355“…The former stimulate fast excitatory neurotransmission, are N-methyl-d-aspartate (NMDA), α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA), and kainate; while the latter are G-protein-coupled receptors that mediate glutamatergic activity via intracellular messenger systems. …”
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3356“…BACKGROUND: Among the multiple mechanisms of action of topiramate, AMPA/kainate antagonism may be particularly interesting for the treatment of disorders characterized by conditioned cognitive and behavioral cue reactivity. …”
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3357por Nair, Ramya, Lauks, Juliane, Jung, SangYong, Cooke, Nancy E., de Wit, Heidi, Brose, Nils, Kilimann, Manfred W., Verhage, Matthijs, Rhee, JeongSeop“…In the absence of Nbea, immature AMPA receptors accumulated early in the biosynthetic pathway, and mature N-methyl-d-aspartate, kainate, and GABA(A) receptors did not reach the synapse, whereas maturation and surface expression of other membrane proteins, synapse formation, and presynaptic function were unaffected. …”
Publicado 2013
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3358por Park, Tae-Joon, Hwang, Joo-Yeon, Go, Min Jin, Lee, Hye-Ja, Jang, Han Byul, Choi, Youngshim, Kang, Jae Heon, Park, Kyung Hee, Choi, Min-Gyu, Song, Jihyun, Kim, Bong-Jo, Lee, Jong-Young“…Although there are some limitations, including genetic power, additional replication and functional characterization will support the clarity on the genetic contribution that the ST6GALNAC3, ADAMTS9, and CELF2 genes have in childhood liver function.…”
Publicado 2013
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3359por Tang, Peng, Yang, Shiping, Zhong, Xiaojie, Yao, Jia, Zhang, Yu, Dong, Huaying, Li, Guanqiao“…Here, we will report on the first case of this type of tumor in the Chinese province of Hainan. The patient was a 19-year-old male, and he underwent a radical mastectomy (RM) with axillary lymph node dissection. …”
Publicado 2015
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3360por Vasconcelos-dos-Santos, Andréia, Oliveira, Isadora A., Lucena, Miguel Clodomiro, Mantuano, Natalia Rodrigues, Whelan, Stephen A., Dias, Wagner Barbosa, Todeschini, Adriane Regina“…The hexosamine biosynthetic pathway is a branch of glucose metabolism that produces UDP-GlcNAc and its derivatives, UDP-GalNAc and CMP-Neu5Ac and donor substrates used in the production of glycoproteins and glycolipids. …”
Publicado 2015
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