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  1. 3401
    “…The most active analogues tested were over 100-fold selective for recombinant GluN2C-containing receptors over GluN2A/B/D-containing NMDA receptors as well as AMPA and kainate receptors. This series represents the first class of allosteric potentiators that are selective for diheteromeric GluN2C-containing NMDA receptors.…”
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    Design, Synthesis, and Structure–Activity Relationship of a Novel Series of GluN2C-Selective Potentiators
  2. 3402
    “…In the present study, we report that DP-b99 delays onset and severity of PTZ-induced seizures in mice, as well as displays neuroprotective effect on kainate excitotoxicity in hippocampal organotypic slices and furthermore blocks morphological reorganization of the dendritic spines evoked by a major neuronal MMP, MMP-9. …”
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    DP-b99 Modulates Matrix Metalloproteinase Activity and Neuronal Plasticity
  3. 3403
    “…Gluazo, as a PCL that targets excitatory amino acid receptors, in its dark-adapted trans iso-form was characterized to be a partial agonist of the kainate glutamate receptor GluK2. Application of UV light leads to the formation of the cis form, with remarkedly reduced affinity towards GluK2. …”
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    Molecular Dynamics Investigation of gluazo, a Photo-Switchable Ligand for the Glutamate Receptor GluK2
  4. 3404
    “…Here we introduce a chemical strategy to covalently conjugate and photoswitch the activity of endogenous proteins and demonstrate its application to the kainate receptor channel GluK1. The approach is based on photoswitchable ligands containing a short-lived, highly reactive anchoring group that is targeted at the protein of interest by ligand affinity. …”
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    Optical control of endogenous receptors and cellular excitability using targeted covalent photoswitches
  5. 3405
    “…PREMISE OF THE STUDY: Chunia bucklandioides (Hamamelidaceae), endemic to Hainan, China, is listed as threatened in the IUCN Red List and is now only found on Mt. …”
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    Isolation and identification of EST-SSR markers in Chunia bucklandioides (Hamamelidaceae)(1)
  6. 3406
    por Kim, Mi-Young
    Publicado 2017
    “…We have recently identified GALNT14, one of the O-GalNAc glycosylation-initiating enzymes, as a prognostic marker for pulmonary relapse in breast cancer patients. …”
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    Role of GALNT14 in lung metastasis of breast cancer
  7. 3407
    “…An aberrant species of Separatatus Chen & Wu, 1994, S. parallelus sp. n., is described from Yunnan and Hainan.…”
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    An illustrated key to the genera and subgenera of the Alysiini (Hymenoptera, Braconidae, Alysiinae), with three genera new for China
  8. 3408
    por Shi, Hongliang, Liang, Hongbin
    Publicado 2018
    “…Four taxa are newly recorded from China: Pericalus ornatus ornatus Schmidt-Göbel (Yunnan, Hainan), P. obtusipennis Fedorenko (Yunnan), P. amplus Andrewes (Yunnan), and P. dux Andrewes (Yunnan). …”
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    Revision of genus Pericalus from China, with descriptions of four new species (Carabidae, Lebiini, Pericalina)
  9. 3409
    “…It was utilized for solid-supported N-to-C peptidomimetic triazole ligation followed by enzymatic glycosylation, ultimately leading to a very large MUC1-derived glycoprotein containing 160 amino acid residues, 24 α-GalNAc moieties linked to Ser and Thr, and 3 triazoles as peptide bond mimetics.…”
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    Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues
  10. 3410
    “…We found in vivo that Cx30 is upregulated by kainate‐induced seizures and that it regulates in turn the severity of associated behavioral seizures. …”
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    Astroglial Cx30 sustains neuronal population bursts independently of gap‐junction mediated biochemical coupling
  11. 3411
    “…Furthermore, we identify triplication of the kainate receptor (KAR) encoding gene Grik1 as the cause of these phenotypes. …”
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    Unbalanced dendritic inhibition of CA1 neurons drives spatial-memory deficits in the Ts2Cje Down syndrome model
  12. 3412
    “…The majority of the sample was female (70%) and black (80%) with a mean age of 82.5 (SD=8.9). Pain (PAINAD) was reported by 36% of the patients; 42% of those demonstrating pain were prescribed analgesics. …”
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    PAIN, PAIN MANAGEMENT, AND CONSEQUENCES OF PAIN AMONG HOSPITALIZED PERSONS WITH DEMENTIA
  13. 3413
    “…Ganoderma ahmadii is one of the main species of Ganoderma fungi distributed in Hainan province of China, the fruiting bodies of which have been used in folk to lower blood sugar for a long time. …”
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    Meroterpenoids With Protein Tyrosine Phosphatase 1B Inhibitory Activities From the Fruiting Bodies of Ganoderma ahmadii
  14. 3414
    “…Wu (Zingiberaceae) is a herbaceous perennial grown in Hainan Province, China, which is an important medicinal plant used for the improvement of gastrointestinal motility. …”
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    Characterization of the complete chloroplast genome of Amomum longiligulare (Zingiberaceae)
  15. 3415
    “…Cymbidium eburneum Lindl. is an endangered species of Orchidaceae and distributed in Guangxi, Yunnan and Hainan of China, and India, Myanmar, Nepal, Vietnam. …”
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    The complete chloroplast genome of Cymbidium eburneum (Orchidaceae)
  16. 3416
    “…Cymbidium nanulum Y.S.Wu & S.C.Chen is an IUCN Red listed Endangered species and distributes in South-Central China and Hainan. Here, we report the complete chloroplast (cp) genome sequence and the cp genome features of C. nanulum. …”
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    The complete chloroplast genome of an Endangered species Cymbidium Nanulum (Orchidaceae)
  17. 3417
    “…Dalbergia tonkinensis is a critically vulnerable tree species that is distributed in Vietnam and Hainan Island of China. The complete chloroplast genome sequence of D. tonkinensis was characterized using Illumina pair-end sequencing. …”
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    The complete chloroplast genome sequence of a vulnerable legume species Dalbergia tonkinensis prain in Vietnam
  18. 3418
    “…Heritiera angustata (Malvaceae) is an evergreen tree distributed in the Chinese provinces of Hainan and Yunnan and in Cambodia. In China, it is listed as ‘Endangered’ (EN) China Red List of Higher Plants, although it is not protected by law. …”
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    Complete chloroplast genome sequence of Heritiera angustata (Malvaceae): an endangered plant species
  19. 3419
    “…The whole mitochondrial genome of the Slender Giant Moray Strophidon sathete (Hamilton, 1822) from the Hainan island was characterized using next-generation sequencing for the first time. …”
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    The complete mitochondrial genome of Slender Giant Moray Strophidon sathete (Hamilton, 1822)
  20. 3420
    “…The degradation half-lives in the Hainan latosol, Yunnan sandy soil, and Fujian Plain alluvial soil were 46.21 days, 36.48 days and 57.76 days, respectively. …”
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    Study on environmental behaviour of fluopyram in different banana planting soil
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