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  1. 3501
    “…Here we show, using an in-vivo remyelination model, that demyelinated axons are electrically active and generate de novo synapses with recruited oligodendrocyte progenitor cells (OPCs), which, early after lesion induction, sense neuronal activity by expressing AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)/kainate receptors. Blocking neuronal activity, axonal vesicular release or AMPA receptors in demyelinated lesions results in reduced remyelination. …”
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    Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors
  2. 3502
    “…Cells incubated with peracetylated benzyl-α-N-acetylgalactosamine (GalNAc-α-Benzyl) convert it to a large variety of modified O-glycan derivatives that are secreted from cells, allowing easy purification for analysis by HPLC and mass spectrometry (MS). …”
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    Cellular O-Glycome Reporter/Amplification to Explore O-Glycans of Living Cells
  3. 3503
    “…Using precollicular transection in 13‐day‐old rats to isolate the forebrain from the brainstem, we demonstrate that the forebrain is not required for generation of tonic–clonic convulsions induced by hyperthermia or kainate. Compared with sham‐operated littermate controls, latency to onset of convulsions in both models was significantly shorter in pups that had undergone precollicular transection, indicating suppression of the brainstem seizure network by the forebrain in the intact animal. …”
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    Forebrain‐independent generation of hyperthermic convulsions in infant rats
  4. 3504
    “…Presynaptic adenosine receptors of the A1R type, but not kainate receptors (KARs), modulate STP behavior. Blocking the receptors does not eliminate diversity, indicating that diversity is related to heterogeneous expression of multiple mechanisms in the pathway from presynaptic calcium influx to neurotransmitter release.…”
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    Presynaptic Adenosine Receptor-Mediated Regulation of Diverse Thalamocortical Short-Term Plasticity in the Mouse Whisker Pathway
  5. 3505
    “…In 2008 and 2010, at least 3 remarkable cholera outbreaks occurred in Hainan, Anhui and Jiangsu provinces of China. To address the possible transmissions and the relationships to the 7(th) pandemic strains of those 3 outbreaks, we sequenced the whole genomes of the outbreak isolates and compared with the global isolates from the 7(th) pandemic. …”
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    The Transmission and Antibiotic Resistance Variation in a Multiple Drug Resistance Clade of Vibrio cholerae Circulating in Multiple Countries in Asia
  6. 3506
    “…We also demonstrate that activating DGH GABAergic interneurons can significantly inhibit the spread of ictal seizures and largely rescue behavioural deficits in kainate-exposed animals. These findings may shed light on future therapeutic treatments of TLE.…”
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    Optogenetic dissection of ictal propagation in the hippocampal–entorhinal cortex structures
  7. 3507
    “…This study determined the pathogenicity of Metarhizium anisopliae strain SD-3 against invasive red palm weevil (RPW), Rhynchophorus ferrugineus Olivier (coleoptera:curculionidae) larvae in Hainan Province, China. Inoculation of 1 × 10(8) conidia/mL caused 100 % mortality of R. ferrugineus, indicating that the conidia of strain SD-3 were highly virulent. …”
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    Frozen section and electron microscopy studies of the infection of the red palm weevil, Rhynchophorus ferrugineus (coleoptera:curculionidae) by the entomopathogenic fungus Metarhizium anisopliae
  8. 3508
    “…EPNs identified in agricultural areas in Brazil were Heterorhabditis amazonensis, Metarhabditis rainai, Oscheios tipulae and Steinernema rarum. These species should be considered pest biocontrol agents in Brazilian agricultural areas.…”
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    Entomopathogenic nematodes in agricultural areas in Brazil
  9. 3509
    “…We designed a high efficacy soma-targeted opsin, finding that fusing the N-terminal 150 residues of kainate receptor subunit 2 (KA2) to the recently discovered high-photocurrent channelrhodopsin CoChR restricted expression of this opsin primarily to the cell body of mammalian cortical neurons. …”
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    Temporally precise single-cell resolution optogenetics
  10. 3510
    “…With the cultivated species strains extracted from wild Morchella spp. in Diebu County, Gannan Prefecture as experimental materials, an experiment was designed and the data then obtained was anyalyzed using the single factor variable method. …”
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    Effects of different cultivation material formulas on the growth and quality of Morchella spp.
  11. 3511
    “…The functional roles of kainate receptors (KARs) are less well defined but they play a role in some forms of synaptic plasticity. …”
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    Proteins Involved in the Trafficking and Functional Synaptic Expression of AMPA and KA Receptors
  12. 3512
    “…The aim of this work was to evaluate the main nutrients and their antioxidant properties of a Chinese wild edible fruit, Passiflora foetida, collected from the ecoregion of Hainan province, China. The analytical results revealed that P. foetida fruits were rich in amino acids (1097 mg/100 g in total), minerals (595.75 mg/100 g in total), and unsaturated fatty acids (74.18 g/100 g in total fat). …”
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    Nutritional Composition and Antioxidant Properties of the Fruits of a Chinese Wild Passiflora foetida
  13. 3513
    “…AJLec was characterized using the hemagglutination assay, isothermal titration calorimetry (ITC), and glycoconjugate microarray analysis and we found that AJLec has a specificity for galactose monomers and β-linked terminal galactose residues in complex carbohydrates, but not for N-acetylgalactosamine (GalNAc), which is commonly recognized by galactose-binding lectins. …”
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    Identification, Characterization, and X-ray Crystallographic Analysis of a Novel Type of Lectin AJLec from the Sea Anemone Anthopleura japonica
  14. 3514
    “…A rapid and sensitive ionic liquid (IL) based headspace gas chromatography-mass spectrometry (HS-GC-MS) method was developed for analyzing volatile components in leaf, pericarp, and seed of Clausena lansium from different areas in Hainan Province, China. HS efficiencies were carefully investigated by using three ILs and water as matrix media. …”
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    Rapid and Sensitive Analysis of Volatile Components of Different Parts of Clausena lansium by Ionic Liquid Based Headspace Gas Chromatography-Mass Spectrometry
  15. 3515
    “…Here, the first near‐infrared imaging probe (named ONP) is presented for tracking endogenous ONOO(−) in brains of kainate‐induced epileptic seizures with high sensitivity and selectivity. …”
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    Imaging Dynamic Peroxynitrite Fluxes in Epileptic Brains with a Near‐Infrared Fluorescent Probe
  16. 3516
    por Wang, Qian, Li, Duo, Chang, Tzu-Han
    Publicado 2019
    “…Lastly, regions with the best technological innovation efficiencies are Beijing, Shanghai, Guangdong, Fujian, Hainan, Hebei, Inner Mongolia, Ningxia, Qinghai, Shandong, Shanxi, Tianjin, Xinjiang, and Yunnan.…”
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    Energy and Health Efficiencies in China with the Inclusion of Technological Innovation
  17. 3517
    “…Herein, four copies of a conformationally constrained mimetic of the antigen TnThr (GalNAc-Thr) were conjugated to the adjuvant CRM197, a protein licensed for human use. …”
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    A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer
  18. 3518
    “…(Magnoliaceae) is an endemic and ornamental tree distributed in Hainan, China. In this study, we report and characterize the complete plastid genome sequence of M. fordiana var. hainanensis in order to provide genomic resources helpful for promoting its conservation and garden utilization. …”
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    Complete plastome sequence of magnolia fordiana var. hainanensis (dandy) Noot. (Magnoliaceae), an endemic and ornamental tree in South China
  19. 3519
    “…The cyprinid genus Onychostoma Günther, 1896 consists of 24 valid species distributed in Southeast Asia, including Taiwan, Hainan, mainland China and the Indochina region. In the present study, we determined the complete mitochondrial genome of O. lepturum, which is 16,598 bp in length, containing 13 protein-coding genes, two rRNA genes, 22 tRNA genes and a typical control region (D-loop). …”
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    Complete mitochondrial genome of the freshwater fish Onychostoma lepturum (Teleostei, Cyprinidae): genome characterization and phylogenetic analysis
  20. 3520
    “…It grows on trees or rocks in forests (100–600 m) in Guangdong and Hainan Province of China. Here, we report and characterize the complete plastid genome sequence of P. laetispicum in an effort to provide genomic resources useful for promoting its conservation. …”
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    Complete plastome sequence of Piper laetispicum (Piperaceae): An endemic plant species in South China
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