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3561por Li, Yanan, Xie, Xin’e, Xing, Hang, Yuan, Xiang, Wang, Yuan, Jin, Yikai, Wang, Jiangang, Vreugdenhil, Martin, Zhao, Ying, Zhang, Ruiling, Lu, Chengbiao“…We explored the effects of multiple intracellular kinases on MA modulation of γ induced by kainate in area CA3 of rat ventral hippocampal slices. …”
Publicado 2019
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3562“…The aim of this work was to compare the composition and physicochemical properties (SEM, XRD, solubility, swelling power, paste clarity, retrogradation, freeze–thaw stability, thermal property, and pasting property) of three Chinese yam (Dioscorea opposita Thunb.) starches (CYYS-1, CYYS-2, and CYYS-3) in Yunlong town, Haikou, Hainan Province, China. Our results show that all the CYYS gave a typical C-type X-ray diffraction pattern. …”
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3563por Needs, Hope I., Henley, Benjamin S., Cavallo, Damiana, Gurung, Sonam, Modebadze, Tamara, Woodhall, Gavin, Henley, Jeremy M.“…Notably, AMPAR subunits were dramatically decreased during the latent phase of epilepsy induction, matched by a profound decrease in the network response to kainate application in the hippocampus. Moreover, decreases in the GABA(A)β3 subunit are consistent with a loss of inhibitory input contributing to the perturbation of excitatory/inhibitory balance and seizure generation. …”
Publicado 2019
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3564por Tykesson, Emil, Maccarana, Marco, Thorsson, Hanna, Liu, Jian, Malmström, Anders, Ellervik, Ulf, Westergren-Thorsson, Gunilla“…Using a microbial K4 polysaccharide and the recombinant enzymes DS-epimerase 1, dermatan 4-O-sulfotransferase 1, uronyl 2-O-sulfotransferase and N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase, several new glycostructures have been prepared, such as a homogenously sulfated IdoA-GalNAc-4S polymer and its 2-O-, 6-O- and 2,6-O-sulfated derivatives. …”
Publicado 2019
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3565por Qiu (Fu-Hsi Ch'iu), Fu-Xi, Tian, Ye, Liu (Chi-Ch'ang Liu), Ji-Chang, Zhang, Xin-Sheng, Hao, Yan-Peng“…Only one out of 50 adult sera from Hainan Island was positive for the antibody.…”
Publicado 1986
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3566por Umpierre, Anthony D, Bystrom, Lauren L, Ying, Yanlu, Liu, Yong U, Worrell, Gregory, Wu, Long-Jun“…However, hyperactive shifts in neuronal activity (kainate status epilepticus and CaMKIIa Gq DREADD activation) triggered increased microglial process calcium signaling, often concomitant with process extension. …”
Publicado 2020
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3567Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins“…The ligand of ASGPR, triantennary N-acetylgalactosamine (tri-GalNAc), was conjugated to biotin, antibodies, or fragments of antibodies to generate a new class of degraders. …”
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3568por Fang, Yan, Li, Xing-hui, Qiao, Yan, Wang, Nan, Xie, Ping, Zhou, Gang, Su, Peng, Ma, Hui-yuan, Song, Ji-yang“…Our study demonstrated that monks in Gannan Tibetan autonomous district had a lower prevalence of dyslipidemia. …”
Publicado 2020
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3569“…It distributed in.south China (e.g., Fujian, Guangdong, Guangxi, Hainan etc) and other south Asian countries (e.g. …”
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3570por Zhang, Libo, Yu, Hai, Bai, Yuanyuan, Mishra, Bijoyananda, Yang, Xiaoxiao, Wang, Jing, Yu, Evan B., Li, Riyao, Chen, Xi“…The binding profiles of six plant lectins with binding preference towards Gal and/or GalNAc, as well as human galectin-3 and galectin-8, were readily obtained. …”
Publicado 2021
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3571por Guo, Zhikai, Ma, Shiying, Khan, Salman, Zhu, Hongjie, Zhang, Bo, Zhang, Shiqing, Jiao, Ruihua“…ITBB-ZKa6, from Zhaoshu island, Hainan, led to the discovery of two unique antimycin-type depsipeptides, zhaoshumycins A (1) and B (2), along with the isolation of the four known neoantimycins A (3), F (4), D (5), and E (6). …”
Publicado 2021
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3572por Hu, Guibing, Feng, Junting, Xiang, Xu, Wang, Jiabao, Salojärvi, Jarkko, Liu, Chengming, Wu, Zhenxian, Zhang, Jisen, Liang, Xinming, Jiang, Zide, Liu, Wei, Ou, Liangxi, Li, Jiawei, Fan, Guangyi, Mai, Yingxiao, Chen, Chengjie, Zhang, Xingtan, Zheng, Jiakun, Zhang, Yanqing, Peng, Hongxiang, Yao, Lixian, Wai, Ching Man, Luo, Xinping, Fu, Jiaxin, Tang, Haibao, Lan, Tianying, Lai, Biao, Sun, Jinhua, Wei, Yongzan, Li, Huanling, Chen, Jiezhen, Huang, Xuming, Yan, Qian, Liu, Xin, McHale, Leah K., Rolling, William, Guyot, Romain, Sankoff, David, Zheng, Chunfang, Albert, Victor A., Ming, Ray, Chen, Houbin, Xia, Rui, Li, Jianguo“…The extremely early maturing cultivars preferentially aligned to one haplotype were domesticated from a wild population in Yunnan, whereas the late-maturing cultivars that mapped mostly to the second haplotype were domesticated independently from a wild population in Hainan. Early maturing cultivars were probably developed in Guangdong via hybridization between extremely early maturing cultivar and late-maturing cultivar individuals. …”
Publicado 2022
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3573por Lu, Mengyao, Sun, Jin, Zhao, Yuning, Zhang, Haowen, Li, Xinyue, Zhou, Jingbo, Dang, Hongyang, Zhang, Jidong, Huang, Wenjing, Qi, Ce, Li, Duo“…OBJECTIVES: Lactobacillus reuteri Fn041 (Fn041) is a probiotic isolated from immunoglobulin A coated microbiota in the human breast milk of Gannan in China with a low incidence of hypercholesterolemia. …”
Publicado 2022
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3574“…During our field work in 2020, we collected a river-weed in Wuzhi Mountain, Hainan Province of China. After checking the morphological characters, it was identified as P.chiangmaiensis. …”
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3575por González-Cuesta, Manuel, Herrera-González, Irene, García-Moreno, M. Isabel, Ashmus, Roger A., Vocadlo, David J., García Fernández, José M., Nanba, Eiji, Higaki, Katsumi, Ortiz Mellet, Carmen“…We have designed sp(2)-iminosugar glycomimetics related to GalNAc that feature a neutral piperidine-derived thiourea or a basic piperidine-thiazolidine bicyclic core and behave as selective nanomolar competitive inhibitors of human Hex A at pH 7 with a ten-fold lower inhibitory potency at pH 5, a good indication for pharmacological chaperoning. …”
Publicado 2022
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3576por Focchi, Elisa, Cambria, Clara, Pizzamiglio, Lara, Murru, Luca, Pelucchi, Silvia, D’Andrea, Laura, Piazza, Silvano, Mattioni, Lorenzo, Passafaro, Maria, Marcello, Elena, Provenzano, Giovanni, Antonucci, Flavia“…A deeper investigation of synaptic composition unveils increased Gluk-1 and Gluk-5 subunit-containing kainate receptors (KARs) levels in the hippocampus, but not in the cortex, of Atm(+/−) and Atm(−/−) mice. …”
Publicado 2022
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3577por Li, Hongquan, Song, Junjiao, He, Yifei, Liu, Yizhe, Liu, Zhen, Sun, Weili, Hu, Weiguo, Lei, Qun‐Ying, Hu, Xin, Chen, Zhiao, He, Xianghuo“…Blocking HK2 or ACSL4 effectively inhibits liver cancer growth, and GalNac‐siHK2 administration specifically targets the growth of orthotopic tumor xenografts. …”
Publicado 2022
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3578“…This study describes the complete mitochondrial genome sequence of the scyphozoan Acromitus flagellatus (Maas, 1903), a blooming jellyfish found in the coastal areas of Hainan, China. Its mitochondrial DNA is 16,779 bp in length and has a linear structure, comprising 13 protein-coding genes (PCGs), two rRNAs (s-rRNA and l-rRNA), and two tRNAs (trna-W-TCA and trna-M-CAT). …”
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3579“…A survey was conducted among 518 tourists who spend their holiday in Hainan, which is a popular tourist destination in China. …”
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3580“…This suggests the existence of a mantle plume, corresponding to the Hainan plume, that originates in the lower mantle, passes through the mantle transition zone, and enters the upper mantle. …”
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