“…Briefly, paired chemical groups (N(3)/BCN) are separately incorporated into CAR-T cell and tumor via nondestructive intrinsic glycometabolism of exogenous Ac(4)GalNAz and Ac(4)ManNBCN, serving as an artificial ligand-receptor. …”
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“…This hydrodynamic model is then utilized to simulate the wave–structure interaction of the prototype SFT designed for Qiongzhou Strait located between Mainland China and Hainan Island. The effects of the fundamental structure parameter, or the inclined mooring angle (IMA), on the dynamic responses of SFT are analyzed. …”
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“…A new native chicken breed, named Danzhou chicken was discovered in Hainan, China in 2014, although identification is difficult by morphological examination alone. …”
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“…Xincun Lagoon is an important fishing area in northern Hainan Island, China. It has long been exposed to pollutants from local sewage, breeding cages and fishing boats, resulting in serious pollution threats to the survival of fish. …”
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“…Microsatellite markers were isolated and characterized for Hopea hainanensis Merrill & Chun, an endangered tree species with scattered distribution in Hainan Island and northern Vietnam. Twenty‐six microsatellite markers were developed based on next‐generation sequencing data and were genotyped by capillary electrophoresis on an ABI 3730xl DNA Analyzer. …”
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“…It is distributed in China (Hainan province), Indonesia, Malaysia (N Borneo), Philippines, Thailand, and Vietnam. …”
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“…Atalantia kwangtungensis (Rutaceae) is a small shrub (1–2 m tall) distributed in moist and shady places throughout evergreen broad-leaved forests having altitudes that range from 100 to 400 m in West Guangdong, Southeast Guangxi, Hainan province of China. It has been ranked as a near threatened (NT) species in China. …”
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“…None of them were positive for lyssavirus, but six bat brains (0.6%) of Rhinolophus bat species, originating from Hubei and Hainan provinces, were positive for vesiculoviruses or ledanteviruses. …”
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“…Following NMR perturbation of W42, which is located in the carbohydrate-binding region of LecA, allowed to monitor binding of low-affinity ligands such as N-acetyl d-galactosamine (d-GalNAc, K(d) = 780 ± 97 μM). Moreover, PrOF NMR titration with glycomimetic of LecA p-nitrophenyl β-d-galactoside (pNPGal, K(d) = 54 ± 6 μM) demonstrated a 6-fold improved binding of d-Gal proving this approach to be valuable for ligand design in future drug discovery campaigns that aim to generate inhibitors of LecA.…”
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“…MUL_3720 bound only to glycans containing sulfated galactose and GalNAc, such as glycans known to be associated with keratins isolated from human skin. …”
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“…In this study, we performed metagenomic sequencing on a susceptible strain (SS), a field-collected Hainan strain (HN), and a deltamethrin-resistant strain (RR) of Culex pipiens quinquefasciatus to understand the diversity and functions of their midgut microbiota. …”
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“…The optical gain spectrum has been investigated theoretically for various designs of active region based on InAs/GaInSb quantum wells—i.e., a type II material system employable in interband cascade lasers (ICLs) or optical amplifiers operating in the mid-infrared spectral range. …”
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“…Here we recruit 1579 participants in Hainan Province, China, and group them by sex. We compared the prediction power of common parameters of T2D in two sexes by association, regression, and Receiver Operating Characteristic (ROC) analysis. …”
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“…The aim of the present study was to elucidate the effect of resveratrol (natural polyphenol) on seizure activity, production of ROS, brain damage and mitochondrial function in the early phase of status epilepticus (SE), induced in immature 12 day-old rats by substances of a different mechanism of action (Li-pilocarpine, DL-homocysteic acid, 4-amino pyridine, and kainate). Seizure activity, production of superoxide anion, brain damage and mitochondrial function were assessed by EEG recordings, hydroethidium method, FluoroJadeB staining and Complex I activity measurement. …”
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“…Our results suggest that TQ modulates the processes leading to post-kainate neuronal death in the CA3 hippocampal area.…”
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“…We utilized the chronic intrahippocampal kainate mouse model of temporal lobe epilepsy, which results in spontaneous seizures and as is often the case in human patients, presents with hippocampal sclerosis. …”
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“…Specifically, PE mothers and FGR fetuses (with or without FGR or PE, respectively) exhibited a pro-atherogenic and pro-inflammatory profile, with higher concentrations of triglycerides, remnant cholesterol (VLDL, IDL) and Glc/GalNAc-linked and lipid-associated glycoproteins compared to controls. …”
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“…Porphyrin glycoconjugates have recently gained attention for their potential to overcome these limitations. …”
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“…In this study, we investigated the phyllosphere bacterial communities of three cigar tobacco varieties cultivated in Guangcun (GC) and Wuzhishan (WZS), Hainan, China. Metagenomic DNA was extracted from tobacco leaf samples and sequenced by 16S rDNA amplicon sequencing. …”
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“…The AMPA, NMDA, Delta and Kainate receptors need the stable underlying actin cytoskeleton to anchor through synaptic proteins for precise synapse formation. …”
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