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4041“…The extended binding site of galectin-4N may not be well suited to the A/B-antigen determinants, α-GalNAc/α-Gal, specifically due to clashes with residue Phe47. …”
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4042por Kaczmarczyk, Lech, Labrie-Dion, Étienne, Sehgal, Kapil, Sylvester, Marc, Skubal, Magdalena, Josten, Michele, Steinhäuser, Christian, De Koninck, Paul, Theis, Martin“…Interestingly, status epilepticus induced by systemic kainate injection in mice led to specific upregulation of the CPEB3 isoforms containing exon seven. …”
Publicado 2016
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4043por Hewitson, James P., Nguyen, D. Linh, van Diepen, Angela, Smit, Cornelis H., Koeleman, Carolien A., McSorley, Henry J., Murray, Janice, Maizels, Rick M., Hokke, Cornelis H.“…Monoclonal antibodies to two immunodominant glycans of H. polygyrus, previously designated Glycans A and B, were found to react by glycan array analysis to a methyl-hexose-rich fraction and to a sulphated LacDiNAc (LDN; GalNAcβ1–4GlcNAc) structure, respectively. We also analysed the glycan repertoire of a major glycoprotein in Heligmosomoides polygyrus excretory–secretory products, VAL-2, which contains many glycan structures present in Heligmosomoides polygyrus excretory–secretory products including Glycan A. …”
Publicado 2016
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4044por Hirano, Arlene A., Liu, Xue, Boulter, Jim, Grove, James, Pérez de Sevilla Müller, Luis, Barnes, Steven, Brecha, Nicholas C.“…Voltage-gated ion channel currents in horizontal cells of Cx57-VGAT(−/−) mice were the same as Cx57-VGAT(+/+) controls, as were the cell responses to the ionotropic glutamate receptor agonist kainate, but the response to the GABA(A) receptor agonist muscimol in Cx57-VGAT(−/−) mice was larger. …”
Publicado 2016
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4045Mucus Sugar Content Shapes the Bacterial Community Structure in Thermally Stressed Acropora muricata“…Increase in the relative abundance of α-Proteobacteria were associated with GalNAc and glucose, while the drop in relative abundance of γ-Proteobacteria at high temperature coincided with changes in fucose and mannose. …”
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4046“…The results indicated that increasing the standardized ileal digestible (SID) of sulfur amino acids (SAA) to lysine (SID SAA:Lys) ratio by supplementation of DL-MHA tended to increase (quadratic; p<0.10) weight gain and ADG, and showed slightly greater (linear; p<0.10) gain:feed ratio. …”
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4047por Wang, Xixi, Long, Wenxing, Schamp, Brandon S., Yang, Xiaobo, Kang, Yong, Xie, Zhixu, Xiong, Menghui“…We measured the species richness and abundance of vascular epiphytes along four vertical crown zones and five horizontal orientations on 376 trees, as well as the diameter at breast height (DBH) of host trees in tropical cloud forests in Bawangling, Hainan, China. The relationship between vascular epiphyte species richness and host tree DBH was assessed using a generalized linear model. …”
Publicado 2016
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4048“…CASE REPORT: A 7-year-old boy from Hainan province in the south of China developed a suppurative corneal ulcer after being in a forest. …”
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4049por Peter, Raphael Simon, Keller, Ferdinand, Klenk, Jochen, Concin, Hans, Nagel, Gabriele“…For men <50 years, highest mortality was observed for steady weight gainers. For all other age-sex groups, mortality was the highest for decreasing trajectories. …”
Publicado 2016
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4050por Restaino, Odile Francesca, di Lauro, Irene, Di Nuzzo, Rosaria, De Rosa, Mario, Schiraldi, Chiara“…In the present study, for the first time, a new capillary electrophoresis method was set up to simultaneously analyse the UDP-glucose (UDP-Glc), UDP-galactose (UDP-Gal), UDP-N-acetylgalactosamine (UDP-GalNAc), UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-glucuronic acid (UDP-GlcA) and the inner CPS portion, extracted at the same time from the bacterial biomasses; separation was performed at 18°C and 18 kV with a borate-based buffer and detection at 200 nm. …”
Publicado 2017
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4051por Inoue, Ryuta, Hirohashi, Yoshihiko, Kitamura, Hiroshi, Nishida, Sachiyo, Murai, Aiko, Takaya, Akari, Yamamoto, Eri, Matsuki, Masahiro, Tanaka, Toshiaki, Kubo, Terufumi, Nakatsugawa, Munehide, Kanaseki, Takayuki, Tsukahara, Tomohide, Sato, Noriyuki, Masumori, Naoya, Torigoe, Toshihiko“…ALDH1(high) cells showed greater sphere-forming ability and higher tumor-initiating ability in immune-deficient mice than those of ALDH1(low) cells, indicating that CSCs/CICs were enriched in ALDH1(high) cells. cDNA microarray analysis revealed that an ionotropic glutamate receptor glutamate receptor, ionotropic, kainate 2 (GRIK2) was expressed in ALDH1(high) cells at a higher level than that in ALDH1(low) cells. …”
Publicado 2017
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4052por Nakagawa, Yasuaki, Nishikimi, Toshio, Kuwahara, Koichiro, Fujishima, Aoi, Oka, Shogo, Tsutamoto, Takayoshi, Kinoshita, Hideyuki, Nakao, Kazuhiro, Cho, Kosai, Inazumi, Hideaki, Okamoto, Hiroyuki, Nishida, Motohiro, Kato, Takao, Fukushima, Hiroyuki, Yamashita, Jun K., Wijnen, Wino J., Creemers, Esther E., Kangawa, Kenji, Minamino, Naoto, Nakao, Kazuwa, Kimura, Takeshi“…Glycosylation at threonines 48 and 71 of human proBNP contributed to the increased secretion of proBNP by attenuating its processing, and GalNAc‐transferase (GALNT) 1 and 2 mediated the glycosylation‐regulated increase in cardiac human proBNP secretion. …”
Publicado 2017
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4053por Grange, Philippe A., Raingeaud, Joël, Morelle, Willy, Marcelin, Anne-Geneviève, Calvez, Vincent, Dupin, Nicolas“…It appears to be highly glycosylated, containing GalNAc residues. Purified DsA1 strongly recognizes the Aα and Bβ subunits of hFg, and specific enzymatic deglycosylation of hFg demonstrated the involvement of the protein backbone in the recognition process. …”
Publicado 2017
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4054“…We conducted real-time monitoring of Hainan sandalwood leaves with varying severity levels of anthracnose and powdery mildew beginning in March 2014. …”
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4055por Sun, Shuaiqi, He, Jun, Zhang, Yao, Xiao, Rongjun, Yan, Mengdan, Ren, Yulin, Zhu, Yuanyuan, Jin, Tianbo, Xia, Ying“…MATERIALS AND METHODS: We evaluated six tagging single-nucleotide polymorphisms (SNPs) of the ALDH2 gene in a case–control study from Hainan of China (488 cases, 503 controls). We used SPSS version 17.0 statistical software, Excel software and other analysis software to explore associations between SNPs and the risk of ischemic stroke various genetic models (additive, dominant, and recessive). …”
Publicado 2017
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4056“…Research on individual trait variation has gained much attention because of its implication for ecosystem functions and community ecology. …”
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4057por Navarro-Lozano, Alba, Sánchez-Domene, David, Rossa-Feres, Denise C., Bosch, Jaime, Sawaya, Ricardo J.“…We examined oral discs of 2156 tadpoles of six species of anurans collected in 2016: Aplastodiscus albosignatus, Boana albopunctata, Boana faber, Scinax hayii, Crossodactylus caramaschii, and Physalaemus cuvieri. …”
Publicado 2018
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4058por Dong, Haijiao, Zhao, Hu, Li, Shuangle, Han, Zhongmin, Hu, Gang, Liu, Chang, Yang, Gaiyu, Wang, Gongwei, Xie, Weibo, Xing, Yongzhong“…Genome-wide association studies (GWAS) identified a total of 40 and 32 QTLs for FLA in Wuhan and Hainan, respectively. Eight QTLs were commonly detected in both conditions. …”
Publicado 2018
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4059“…In PTM-ssMP we provide efficient prediction of multiple types of PTM site including phosphorylation, lysine acetylation, ubiquitination, sumoylation, methylation, O-GalNAc, O-GlcNAc, sulfation and proteolytic cleavage. …”
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4060por Farkas, Imre, Bálint, Flóra, Farkas, Erzsébet, Vastagh, Csaba, Fekete, Csaba, Liposits, Zsolt“…Accordingly, estradiol facilitated neurotransmissions to GnRH neurons via both GABA(A)-R and glutamate/AMPA/kainate-R. These results indicate that estradiol acts directly on GnRH neurons via the ERβ/Akt/nNOS pathway at proestrus afternoon generating NO that retrogradely accelerates GABA and glutamate release from the presynaptic terminals contacting GnRH neurons. …”
Publicado 2018
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